A5007436515- Landslides and related hazards
- Rock Mechanics and Modeling
- Grouting, Rheology, and Soil Mechanics
- Climate change and permafrost
- Dam Engineering and Safety
- Cryospheric studies and observations
- Geotechnical and Geomechanical Engineering
- RNA modifications and cancer
- Groundwater flow and contamination studies
- Epigenetics and DNA Methylation
- Biochemical and Molecular Research
- Tunneling and Rock Mechanics
- Geotechnical Engineering and Analysis
- Advanced Sensor and Energy Harvesting Materials
- Phase Change Materials Research
- Thermal Radiation and Cooling Technologies
- Fluid Dynamics Simulations and Interactions
- Bioinformatics and Genomic Networks
- Magnetic Properties and Applications
- Winter Sports Injuries and Performance
- Advanced Thermoelectric Materials and Devices
- Geomechanics and Mining Engineering
- Electrospun Nanofibers in Biomedical Applications
- Silk-based biomaterials and applications
- Lattice Boltzmann Simulation Studies
Sir Run Run Shaw Hospital
2025
Zhejiang University
2025
Hangzhou Medical College
2025
Hebei University of Technology
1988-2024
Donghua University
2023
Rheumatoid arthritis (RA) is a debilitating systemic autoimmune disorder that significantly impairs quality of life. To elucidate the molecular alterations in RA progression, we performed comprehensive super-omics analyses on synovial tissues from patients with joint trauma, arthritis, and RA. These included transcriptomics, proteomics, metabolomics, microbiomics, fourteen PTMs (phosphorylation, acetylation, lactylation, O-GlcNAc glycosylation, arginine monomethylation, lysine dimethylation,...
Breast cancer is one of the most prevalent cancers among women, and early diagnosis crucial in reducing mortality rate. This study aims to identify novel, reliable, specific biomarkers for breast using 5-Hydroxymethylcytosine (5hmC) signatures circulating cell-free DNA (cfDNA). We utilized sensitive 5hmC seal method map profiles cfDNA samples from 203 patients 60 healthy individuals. Machine learning models were applied marker with high sensitivity specificity. A global loss was observed...
Silk fibroin (SF)-based materials are characterized by their outstanding biocompatibility and biodegradability considered as the most promising candidates for next-generation flexible electronics. In order to generate such devices, SF can be mixed with carbon nanotubes (CNTs) which feature excellent mechanical, electrical, thermal properties. However, obtaining regenerated homogeneous dispersion of CNTs in a sustainable manner represents challenging task, mainly due difficulty overcoming van...
Glacier collapses can occur due to shear failure at the ice-rich debris–rock interface (IDRI). To examine behavior of IDRI, tests were conducted on artificial IDRI specimens with varying ice contents (40%, 65%, and 90%), normal stresses (150, 250, 350, 450, 550 kPa), temperatures (−1, −3, −5, −7, −9 °C). Our findings reveal that temperature has most significant impact both peak residual strength, followed by stress content. As increases from −1 °C, decreased 62.5%–78%. Notably, for lowest...
Triaxial cyclic loading-unloading experiments on red sandstones were carried out under 6 kinds of confining pressures the MTS 816 test system. Total energy density, elastic density and dissipated absorbed by rock specimens different obtained. Evolution process accumulation dissipation pressure effect distribution law analyzed, to reveal conversion mechanism from deformation failure. The equations in stress-strain stages established. results showed with rise pressure, characteristic increased...
A three-dimensional finite-element method is used for calculating the distributions of both temperature field and magnetostatic in a lifting magnet. This 2-D nonlinear problem can be defined by curl-curl equation, 3-D governed Poisson equation. stereoscopic diagram distribution given.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>