A5058574894- Spine and Intervertebral Disc Pathology
- Circular RNAs in diseases
- Spinal Fractures and Fixation Techniques
- Temporomandibular Joint Disorders
- Oropharyngeal Anatomy and Pathologies
- Ferroptosis and cancer prognosis
- Botulinum Toxin and Related Neurological Disorders
- Biomarkers in Disease Mechanisms
- Medical Imaging and Analysis
- Cancer-related molecular mechanisms research
- Cervical and Thoracic Myelopathy
- MicroRNA in disease regulation
- Reconstructive Surgery and Microvascular Techniques
- Bone and Joint Diseases
- Musculoskeletal pain and rehabilitation
- Innovations in Medical Education
- Spinal Hematomas and Complications
- Bone Metabolism and Diseases
- Oral Health Pathology and Treatment
- Osteoarthritis Treatment and Mechanisms
- Myofascial pain diagnosis and treatment
- Innovative Teaching Methods
- Pregnancy-related medical research
- Pelvic and Acetabular Injuries
- Medical and Biological Ozone Research
Xiamen University
2024-2025
Qilu Hospital of Shandong University
2022-2025
Peking Union Medical College Hospital
2025
Chinese Academy of Medical Sciences & Peking Union Medical College
2025
Shandong University
2021-2024
Qingdao University
2022
Affiliated Hospital of Qingdao University
2022
Beijing Jiaotong University
2013
Stem cell transplantation is proven to be a promising strategy for intervertebral disc degeneration (IDD) repair. However, replicative senescence of bone marrow-derived mesenchymal stem cells (BMSCs), shear damage during direct injection, mechanical stress, and the reactive oxygen species (ROS)-rich microenvironment in degenerative discs (IVDs) cause significant cellular limit therapeutic efficacy. Here, an injectable manganese oxide (MnOx)-functionalized thermosensitive nanohydrogel...
SOX9 is a crucial transcriptional regulator of cartilage development and homeostasis. Dysregulation associated with wide spectrum skeletal disorders, including campomelic dysplasia, acampomelic scoliosis. Yet how variants contribute to the axial disorders not well understood. Here, we report four pathogenic identified in cohort patients congenital vertebral malformations. We missense variant transactivation middle (TAM) domain mild dysplasia isolated Sox9 mutant mouse an in-frame...
To provide a comprehensive analysis of the epidemiological characteristics and clinical features pathogens explore risk factors for post-liver transplant (LT) bacterial infections. A retrospective was conducted at Xiang'an Hospital Xiamen University First Affiliated Zhengzhou between 2021 2024. Binary logistic regression performed to identify independent factors, including genetic polymorphisms related infections within first month after LT. Two hundred forty-two liver donors recipients were...
Objective: This study aimed to investigate the selected anatomical factors that can potentially influence temporomandibular joint (TMJ) clicking in young adults by assessing TMJ structures and lateral pterygoid muscle (LPM) function using magnetic resonance imaging (MRI). Methods: The patients were divided into four groups: healthy control group; on mouth opening closing group. Additionally, we used clinical palpation evaluate masticatory muscles' functional state employed MRI...
Objective This study aims to compare the differences between traditional class teaching model and novel flipped in orthopedic surgery, further clarify potential merits. Methods Total 138 undergraduate fourth-year students from Shandong University who interned Orthopedics Department of Qilu Hospital June 2022 2023 were enrolled. They randomly classified into group group. At end internship, all evaluated terms theoretical knowledge practical operations. In addition, they also filled out...
To investigate the size and morphology of temporomandibular joint (TMJ) articular disc condyle in young asymptomatic adults by using magnetic resonance imaging (MRI) to provide a reference for clinical diagnosis scientific study disorders (TMD).Overall, 93 undergraduate volunteers without TMD were enrolled from freshmen pool at Qingdao University. All participants underwent MRI oblique sagittal coronal TMJ planes. The subsequently measured, their was evaluated. obtained data then grouped...
Single-track Gray code is a special class of codes that all the columns its codewords are shifted equivalent. The upper bound single-track discussed on necklace orderings and self-dual orderings. As no length n period 2 <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">n</sup> exists, extra reading heads inevitable to obtain in worst situation 2n may have be used. To solve this problem, subdivision defined. Combining code, double-track can...
Intervertebral disc degeneration (IDD) is a common chronic inflammatory degenerative disease that causes lower back pain. However, the underlying mechanisms of IDD remain unclear. Ferroptosis suppressor protein 1 (FSP1) newly identified for ferroptosis. This study aims to investigate role FSP1 in IDD. Nucleus pulposus (NP) tissues humans were collected and NP cells from rats isolated detect expression pattern. The relationship between FSP1-mediated ferroptosis apoptosis was using inhibitor...
Thoracolumbar fractures are one of the most common in clinical practice. Surgical intervention is recommended to restore spinal alignment or decompress nerves when there unstable neurological injuries. However, after excessive forward thrust force restoration, facet joint dislocation often occurs between upper vertebra and fractured vertebra, which usually leads unsatisfactory reduction outcomes. Herein, we propose a novel toothed plate assist fracture reduction. The purpose this study...
Postoperative spontaneous spinal epidural hematoma (SSEDH) is a rare complication in clinical practice. Despite its rarity, SSEDH critical emergency situation associated with neurological deficits, and improper or delayed management may lead to severe consequences. Therefore, surgical operators should familiarize themselves give it more attention.
Abstract The liver plays a crucial role in the immune response during endotoxemia and is one of critical targets for sepsis-related injuries. As secretory factor involved inflammation, pentraxin-3 (PTX3) has been demonstrated to regulate hepatic homeostasis; however, relationship between PTX3 cell crosstalk cells hepatocytes remains incompletely understood. In this study, we revealed that, compared with WT mice, Ptx3 −/− mice lipopolysaccharide (LPS)-induced exhibited alleviated damage,...
Although Caspar cervical retractor system (CCRS) is commonly utilized in anterior decompression and fixation (ACDF), most urban hospitals still use both traditional S CCRS conventional surgeries. Related data to evaluate the effect are required be reported. The aim of this study compare efficacy between using ACDF.The retrospective that total 360 patients received ACDF different retractors (traditional or CCRS) were enrolled from January 2010 2020. Width change rate prevertebral soft tissue,...
Endometrial carcinoma is a common malignancy among peri-menopausal and menopausal females, even some women of reproductive age. The treatment approach to endometrial cancer platinum-based regimen combined with paclitaxel, which may be unsatisfactory. A copper-mediated binding lipoylated constituents tricarboxylic acid cycle has been found recently, brings about lethal protein stress cell death, phenomenon termed cuproptosis. As an innovative method cuproptosis could designed for many aspects...