A5023413356- Reproductive Biology and Fertility
- Ovarian function and disorders
- Reproductive Health and Technologies
- Prenatal Screening and Diagnostics
- Assisted Reproductive Technology and Twin Pregnancy
- Reproductive System and Pregnancy
- Animal Genetics and Reproduction
- Sperm and Testicular Function
- Genomic variations and chromosomal abnormalities
- Reproductive Health and Contraception
- Ectopic Pregnancy Diagnosis and Management
- Pluripotent Stem Cells Research
- Vitamin D Research Studies
- Hematopoietic Stem Cell Transplantation
- Date Palm Research Studies
- COVID-19 Impact on Reproduction
- Plant and animal studies
- Chromosomal and Genetic Variations
- Phosphodiesterase function and regulation
- Insect Pest Control Strategies
- Pregnancy and preeclampsia studies
- Historical Gender and Feminism Studies
- Human Rights and Immigration
- Seed Germination and Physiology
- Pregnancy and Medication Impact
Nemours Children’s Clinic
2023
Group for the Analysis of Development
2014-2019
Reprogenetics
2015-2017
Millennium Institute of Oceanography
2017
Vrije Universiteit Brussel
2013-2015
Universidad Ricardo Palma
2015
National University of San Marcos
2015
Universitair Ziekenhuis Brussel
2011-2014
What is the influence of vitamin D deficiency on pregnancy rates among women undergoing IVF/ICSI and Day 5 (blastocyst stage) single embryo transfer (SET)?Vitamin results in significantly lower blastocyst transfer.Preliminary experiments have identified presence receptors female reproductive system. However, regarding effect clinical outcomes are conflicting. None previous studies adopted a SET strategy.Serum concentration was measured retrospectively patients who underwent 5. Overall 368...
Does heparin ablate the advantageous effects of cyclic adenosine mono-phosphate (cAMP) modulators during pre-in vitro maturation (IVM) and have a deleterious effect in standard oocyte IVM? Heparin interrupts energy metabolism meiotic progression adversely affects subsequent development oocytes under conditions elevated cAMP levels cumulus-oocyte complexes (COCs) after pre-IVM treatment with forskolin. In animal IVM studies, artificial regulation resumption by cAMP-elevating agents improves...
Human induced pluripotent stem cells (hiPSCs) show great promise in the development of novel strategies to mitigate reproductive diseases and promote successful outcomes. Recently, a approach for fast efficient differentiation ovarian support (OSCs) generate versatile platform basic research clinical applications was demonstrated. This study details process application an OSC product, known as Fertilo, improve vitro maturation (IVM) human oocytes, method referred OSC-IVM. First,...
Which baseline patient characteristics can help assisted reproductive technology practitioners to identify patients who are suitable for in-vitro maturation (IVM) treatment?In with polycystic ovary syndrome (PCOS) undergo oocyte IVM in a non-hCG-triggered system, circulating anti-Müllerian hormone (AMH), antral follicle count (AFC) and total testosterone independently related the number of immature oocytes hold promise as outcome predictors guide selection process IVM.Patient criteria...
STUDY QUESTIONDo cleavage-stage embryos obtained from oocytes matured in vitro after pre-incubation with a phosphodiesterase inhibitor (IBMX) carry more chromosomal abnormalities than those generated vivo?
Abstract STUDY QUESTION Can in vitro maturation (IVM) and developmental competence of human oocytes be improved by co-culture with ovarian support cells (OSCs) derived from human-induced pluripotent stem (hiPSCs)? SUMMARY ANSWER OSC-IVM significantly improves the rates metaphase II (MII) formation euploid Day 5 or 6 blastocyst formation, when compared to a commercially available IVM system. WHAT IS KNOWN ALREADY has historically shown highly variable performance maturing generating strong...
Within the context of an oocyte in vitro maturation (IVM) program for reproductive treatment, cumulus complexes (COCs) derived from follicles <6 mm patients with PCOS were matured vitro. Key transcripts related to meiotic (FSHR, LHCGR, EGFR, PGR) and competence (AREG, ADAMTS, HAS2, PTGS2) quantified cells (CCs) before after maturation. Control CC samples collected normo-ovulatory who had undergone conventional gonadotrophin stimulation IVF/ICSI. Additional control a non-stimulated condition...
To examine whether ovarian puncture for immature oocyte retrieval and in-vitro maturation (IVM) has an effect on the endocrine profile of patients with polycystic ovary syndrome (PCOS). Twenty-two consecutive PCOS undergoing IVM treatment were included. Serum anti-Müllerian hormone (AMH), sex hormone-binding globulin (SHBG), total testosterone (TT) luteinized (LH) levels analyzed at start cycle, day (OR) fixed intervals thereafter, up to three months after OR. Five days OR circulating AMH,...
Abstract Study question What factors are associated with an increased probability of having aneuploid or mosaic embryos in vitro? Summary answer Maternal age and biopsy day significantly influence aneuploidy, while trophectoderm quality impacts both aneuploidy embryo mosaicism. is known already Embryonic mosaicism critical affecting the success vitro fertilization. Several studies have demonstrated that advanced maternal most important variable chromosomal abnormalities. However, other...
Abstract Assisted reproductive technologies (ART) have significantly impacted fertility treatment worldwide through innovations such as in vitro fertilization (IVF) and maturation (IVM). IVM holds promise a technology for women who cannot or do not wish to undergo conventional controlled ovarian stimulation (COS). However, has historically shown highly variable performance maturing oocytes generating with strong developmental capacity. Furthermore, recently reported novel approaches are...
To describe our fertility preservation program focusing on the number of oocytes vitrified by age.From January 2015 to December 2016, 686 oocyte vitrification cycles were performed in units for social program. In total, 288 donors who donated their oocyte-banking program, and 398 patients underwent elective preservation.The mean numbers COCs retrieved similar among donor (women under 30 years). those over 36 years age significantly lower. We also estimated association between cancelation...