A5101474679- Spectroscopy and Laser Applications
- Terahertz technology and applications
- Superconducting and THz Device Technology
- Cellular Mechanics and Interactions
- Advanced Fluorescence Microscopy Techniques
- 3D Printing in Biomedical Research
- Microfluidic and Bio-sensing Technologies
- Semiconductor Quantum Structures and Devices
- Antenna Design and Analysis
- Analog and Mixed-Signal Circuit Design
- Thin-Film Transistor Technologies
- Electromagnetic Compatibility and Measurements
- Electromagnetic Compatibility and Noise Suppression
- Analytical Chemistry and Sensors
- Microfluidic and Capillary Electrophoresis Applications
- Viral Infectious Diseases and Gene Expression in Insects
- Monoclonal and Polyclonal Antibodies Research
- Silicon Nanostructures and Photoluminescence
- Microwave Engineering and Waveguides
- GaN-based semiconductor devices and materials
- Noise Effects and Management
- Energy Harvesting in Wireless Networks
- Atmospheric Ozone and Climate
- CRISPR and Genetic Engineering
- Advanced Wireless Communication Technologies
Southwest University of Science and Technology
2022-2025
University of California, Los Angeles
2018-2025
National Cheng Kung University
2020-2024
ITRI International
2009-2023
National Taiwan University
2010-2022
National Kaohsiung University of Science and Technology
2022
Industrial Technology Research Institute
2009-2022
National Tsing Hua University
2022
California NanoSystems Institute
2021
Nanosys (United States)
2021
Various populations of cells are recruited to the heart after cardiac injury, but little is known about whether cardiomyocytes directly regulate repair. Using a murine model ischemic we demonstrate that play pivotal role in repair by regulating nucleotide metabolism and fates nonmyocytes. Cardiac injury induced expression ectonucleotidase ectonucleotide pyrophosphatase/phosphodiesterase 1 (ENPP1), which hydrolyzes extracellular ATP form AMP. In response AMP, released adenine specific...
We introduce an acoustic microfluidic platform that efficiently traps and selectively releases individual cells using spherical air cavities embedded in a polydimethylsiloxane (PDMS) substrate for large scale manipulation.
The high sensitivity detection of terahertz radiation is crucial for many chemical sensing, biomedical imaging, security screening, nondestructive quality control, high-data-rate communication, atmospheric, and astrophysics sensing applications. Among various techniques, heterodyne great interest applications that require spectral resolution. Heterodyne involves mixing the received with a reference signal provided by local oscillator then down-converting it to an intermediate frequency...
Antrodia cinnamomea (formerly A. camphorata) has recently and commercially been used in the formulation of nutraceuticals functional foods Taiwan. Because its diverse properties, neuroprotective effect was investigated using a fermented extract this study. Serum deprivation-induced apoptosis neuronal-like pheochromocytoma (PC12) cells as cell stress model, it found that effective preventing serum-deprived according to results an MTT assay Hoechst staining. deprivation resulted decreased...
Abstract Motivation: Identification of disease-related genes using high-throughput microarray data is more difficult for complex diseases as compared with monogenic ones. We hypothesized that an endophenotype derived from transcriptional associated a set corresponding to pathway cluster. assumed disease multiple endophenotypes and can be induced by their up/downregulated gene expression patterns. Thus, neural network model was adopted simulate the gene–endophenotype–disease relationship in...
This paper presents a balanced antipodal Vivaldi antenna design to produce ultra-broadband radiations from microwave millimeter-wave frequencies. In particular, this work relaxes the constraints in [1] optimize geometrical parameters broaden operational frequency bandwidth, where 147% relative bandwidth has been achieved. Moreover, optimized design, beam squint and cross-polarization (X-pol) discrepancy at high frequencies are improved by pairing two mirror-imaged structures form an...
We present a heterodyne terahertz spectrometry platform based on plasmonic photomixing, which enables the resolution of narrow spectral signatures gases over broad frequency range. This spectrometer replaces mixer and local oscillator conventional spectrometers with photomixer heterodyning optical pump beam, respectively. The beam is formed by two continuous-wave, wavelength-tunable lasers broadly tunable beat frequency. bandwidth, not restricted bandwidth limitations mixers oscillators. use...
We designed an InAs coupled quantum-dot (QD) structure with a GaAsSb spacer to form intermediate band (IB). The electron and hole states are calculated using the k ⋅ p method. numerical results revealed alignment changes be quasi-type-II 16% Sb. 1 nm AlAs layers around QD GaAs layer help in broadening intraband absorption spectrum from far infrared region range. coupling 8.5 Sb concentration exhibits better photoelectric efficiency for solar cell simulation, 3.3% enhancement of same PIN as...
Photon detection with quantum-level sensitivity is particularly challenging in the terahertz regime (0.1-10 THz), which contains ~98% of all photons existing universe. Near-quantum-limited spectrometry has so far only been possible through use cryogenically cooled superconducting mixers as frequency downconverters. Here we introduce a scheme that uses plasmonic photomixing for downconversion to offer sensitivities at room temperature first time. Frequency achieved by mixing radiation and...
This letter introduces a novel resonator-based suppressor to mitigate the noise transfer on metal plates inside electronic devices. Compared with traditional method using ferrite-based absorbers, which is inadequate fully eliminate gigahertz (GHz) noise, proposed solution can achieve high-level rejection within desired frequency band in GHz range. The unit cell of composed multiple quarter-wavelength (λ /4) strip resonators. By simply cascading cells series, higher-order be implemented wider...
Acoustic patterning of micro-particles has many important biomedical applications. However, fabrication such microdevices is costly and labor-intensive. Among conventional methods, photo-lithography provides high resolution but expensive time consuming, not ideal for rapid prototyping testing academic In this work, we demonstrate a highly efficient method acoustic devices using laser manufacturing. With can fabricate newly designed functional device in 4 hours. The fabricated achieve...
Mapping cellular activities over large areas is crucial for understanding the collective behaviors of multicellular systems. Biomechanical properties, such as traction force, serve critical regulators physiological states and molecular configurations. However, existing technologies mapping large-area biomechanical dynamics are limited by small field view scanning nature. To address this, we propose a novel platform that utilizes vast number optical diffractive elements dynamics. This...
In this work, a smart temperature sensing chip is proposed for the applications of internet-of-things and wearable devices. A resistor-based bridge integrated with fully differential difference amplifier, 10-bit successive approximation analog-to-digital converter, timing circuits into single chip. This designed to sense once per second, activated only 64 μS second stays in standby mode rest time reducing power consumption. The fabricated by 0.18μm 1P6M mixed-signal process, total area...
This paper presents a CMOS/microfluidics pointof-care (PoC)SoC for molecular detection using DNA aptamers and CRISPR-associated enzymes (Cas). We take advantage of the signaling property from electron transfers redox reporters present square-wave voltcoulometry (SWVC) electrochemical readout circuit to achieve $\gt 100\times$ signal enhancement. The SoC is implemented in 180-nm CMOS technology, integrated with pH temperature sensors, consumes total power 2.4mW.