A5100387080- Terahertz technology and applications
- NF-κB Signaling Pathways
- Spectroscopy and Laser Applications
- Botanical Research and Applications
- Photonic and Optical Devices
- Superconducting and THz Device Technology
- Biocrusts and Microbial Ecology
- Immune Response and Inflammation
- Ion channel regulation and function
- Cardiac electrophysiology and arrhythmias
- Plant Water Relations and Carbon Dynamics
- Advanced Data Storage Technologies
- HIV, Drug Use, Sexual Risk
- Cardiovascular and Diving-Related Complications
- Simulation Techniques and Applications
- Statistical Methods in Clinical Trials
- Cell death mechanisms and regulation
- Cardiac Fibrosis and Remodeling
- Sex work and related issues
- Ion Channels and Receptors
- Genomics, phytochemicals, and oxidative stress
- Restraint-Related Deaths
- Polysaccharides and Plant Cell Walls
- Traumatic Brain Injury and Neurovascular Disturbances
- Plant nutrient uptake and metabolism
Second Affiliated Hospital of Zhejiang University
2022
University of California, Los Angeles
1995-2021
QB3
2021
University of Pennsylvania
2018
Hubei University of Medicine
2017
University of Michigan–Ann Arbor
1991-2016
Army Medical University
2016
Southwest Hospital
2016
University of Rochester Medical Center
2014
Shantou University
2011
Abstract Excessive activation of the TLR4 signalling pathway is critical for inflammation-associated disorders, while negative regulators play key roles in restraining from over-activation. Naringenin a citrus flavonoid with remarkable anti-inflammatory activity, but mechanisms underlying its inhibition LPS/TLR4 are less clear. This study investigated molecular targets and therapeutic effects naringenin vitro vivo . In LPS-stimulated murine macrophages, suppressed expression TNF-α, IL-6,...
Four oligofructans (neokestose, 1-kestose, nystose, and an un-identified pentofructan) occurred in the vascular tissues phloem sap of mature leaves Agave deserti. Fructosyltransferases (responsible for fructan biosynthesis) also tissues. In contrast, fructosyltransferases were virtually absent from chlorenchyma, suggesting that biosynthesis was restricted to On a molar basis, these accounted 46% total soluble sugars (sucrose [Suc] 26%) 19% (fructose 24% Suc 53%). The concentration 1.8 times...
Abstract High-throughput biological data analysis commonly involves identifying features such as genes, genomic regions, and proteins, whose values differ between two conditions, from numerous measured simultaneously. The most widely used criterion to ensure the reliability is false discovery rate (FDR), which primarily controlled based on p -values. However, obtaining valid -values relies either reasonable assumptions of distribution or large numbers replicates under both conditions....
Aberrant activation of inflammation signaling triggered by tumor necrosis factor α (TNF-α), interleukin-1 (IL-1), and interleukin-17 (IL-17) is associated with immunopathology. Here, we identify neural precursor cells expressed developmentally down-regulated gene 4-like (NEDD4L), a HECT type E3 ligase, as common negative regulator induced TNF-α, IL-1, IL-17. NEDD4L modulates the degradation mitogen-activated protein kinase 2 (MEKK2) via constitutively directly binding to MEKK2 promotes its...
The effectiveness of immune responses depends on the precision stimulus-responsive gene expression programs. Cells specify which genes to express by activating stimulus-specific combinations stimulus-induced transcription factors (TFs). Their activities are decoded a regulatory strategy (GRS) associated with each response gene. Here, we examined whether GRSs target may be inferred from stimulus-response (input-output) datasets, remains an unresolved model-identifiability challenge. We...
<h3>Background:</h3> Clients of female sex workers (CFSWs) are at risk for HIV transmission; relevant surveillance and interventions this vulnerable group scarce. The China-UK HIV/AIDS Prevention Care Project launched an enhanced intervention programme involving peer education, seminars, testing services social gatherings so forth, two behavioural studies (BSS) targeting CFSWs in Suining, Sichuan. <h3>Methods:</h3> Two cross-sectional BSS (a baseline survey evaluative survey) were conducted...
After exposure to a doubled CO2 concentration of 750 [mu]mol mol-1 air for about 3 months glucose and starch in the chlorenchyma basal cladodes Opuntia ficus-indica increased 175 57%, respectively, compared with current 370 mol-1, but sucrose content was virtually unaffected. Doubling nocturnal malate production by 75%, inorganic phosphate (Pi) 32%, soluble synthase activity 30%, sucrose-Pi 146%, did not affect hexokinase. accelerated phloem transport out cladodes, resulting 73% higher dry...
Journal Article Phloem Exudate Collected via Scale Insect Stylets for the CAM Species Opuntia ficus-indica under Current and Doubled CO2 Concentrations Get access Ning Wang, Wang Search other works by this author on: Oxford Academic PubMed Google Scholar Park S. Nobel Annals of Botany, Volume 75, Issue 5, May 1995, Pages 525–532, https://doi.org/10.1006/anbo.1995.1054 Published: 01 1995
Gliomas are highly malignant brain tumors. Aberrant activation of NF-κB plays a crucial role in tumor progression.ELISA assay was used to detect activity glimoas cells with different treatments. PPP3CC expression evaluated by qRT-PCR and western blot assay. Kaplan-Meier analysis estimated the overall survival rates according protein level PPP3CC. Transwell MTS were performed determine cell invasion growth. Chromatin immunoprecipitation combined luciferase reporter assays illustrated...
Phloem versus xylem water and carbon flow between a developing daughter cladode (flattened stem segment) the underlying basal of Opuntia ficus-indica was assessed using net CO2 uptake, transpiration, phloem sap concentration, potential both organs as well apoplastic tracers. A 14-d-old sink organ with negative daily uptake; its higher than that cladode, implicating non-xylem pathway for needed growth. Indeed, relatively dilute (7.44% dry weight) can supply all (7.1 gd−1) along photosynthate...
Abstract High-throughput biological data analysis commonly involves identifying features such as genes, genomic regions, and proteins, whose values differ between two conditions, from numerous measured simultaneously. The most widely-used criterion to ensure the reliability is false discovery rate (FDR), which primarily controlled based on p-values. However, obtaining valid p-values relies either reasonable assumptions of distribution or large numbers replicates under both conditions....
The variegated leaves of the Crassulacean acid metabolism (CAM) species Agave americana have a large central longitudinal green band with narrow yellow bands on either side. had 97% less pigment content, 84% lower ribulose‐1,5‐bisphosphate carboxylase/oxygenase activity, but only 20% phosphoenolpyruvate carboxylase activity than band. exhibited gas exchange typical CAM plants, most CO 2 uptake occurring at night, leading to daily net 127 mmol m −2 day −1 . some nighttime larger loss during...
We present a technique for high-precision millimeter-wave frequency determination through plasmonic photomixing. Our utilizes photomixer pumped by an optical comb with high-stability beat frequency. The down-converts the signal to radio regime at which high-accuracy counters are available. precision of this is determined stability frequency, can be directly characterized in presented experimental setup. demonstrate measurement as low 3.9×10-10 95 GHz photomixing without phase-locking comb.
High power sources and high sensitivity detectors are in demand for any terahertz imaging sensing system. Incorporating plasmonic contact electrodes photoconductive has proved to offer higher radiation powers detection sensitivities by enhancing the photoconductor quantum efficiency significantly. This is because of unique capability manipulating concentration photocarriers near electrodes, allowing a larger number reach within oscillation cycle efficiently contribute detection. The impact...
We present a compact, room-temperature, high-power and broadly tunable terahertz source based on two-section digital distributed feedback laser diode plasmonic photomixer. It offers 3 THz radiation frequency tuning range with power of 0.45 mW at 1.62 THz.
Lead, an endocrine disrupting chemical (EDC), has been related to delays in weight and pubertal onset, but limited data account for metabolic mechanisms. We examined the additional variance Body Mass Index (BMI), estradiol testosterone among n=40 children aged 7–15 yr predicted by metabolomics, using a multi‐index model with variable selection construct 2 indices % methylation of CpG sites utero peripuberty 4 candidate genes associated physical growth each built from 317 metabolites known...
We demonstrate a new class of terahertz spectrometers that use plasmonic photomixers as frequency downconverters to offer quantum-level sensitivity at room temperature. demonstrated double-sideband noise temperatures 120–270 K (10hv/k -2hv/k) over 0.1–2 THz, equivalent 10-2 photons.
We characterize sensitivity of plasmonic heterodyne terahertz spectrometers using standard Y-factor noise temperature measurements and demonstrate near-quantum-limited sensitivities at room temperature. double-sideband temperatures 120-270 Kover 0.1-2 THz.