A5047326383- Diet and metabolism studies
- Pancreatic and Hepatic Oncology Research
- Clinical Nutrition and Gastroenterology
- Metabolism, Diabetes, and Cancer
- Gastric Cancer Management and Outcomes
- Aortic Disease and Treatment Approaches
- Trauma Management and Diagnosis
- Hepatocellular Carcinoma Treatment and Prognosis
- Neuroendocrine Tumor Research Advances
- Cardiac Arrest and Resuscitation
- Anorectal Disease Treatments and Outcomes
- Gastrointestinal motility and disorders
- Myofascial pain diagnosis and treatment
- Growth Hormone and Insulin-like Growth Factors
- Digestive system and related health
- Trauma and Emergency Care Studies
- Cancer Genomics and Diagnostics
- Pectus Deformity Diagnosis and Treatment
- Inhalation and Respiratory Drug Delivery
- Herpesvirus Infections and Treatments
- Pathogenesis and Treatment of Hiccups
- Enhanced Recovery After Surgery
- Ultrasound in Clinical Applications
- RNA regulation and disease
- Musicians’ Health and Performance
University of Wisconsin–Madison
2011-2025
Roswell Park Comprehensive Cancer Center
2023-2024
UW Health University Hospital
2014-2020
Vanderbilt University Medical Center
2017
University of Wisconsin American Family Children's Hospital
2015
Highland Community College - Illinois
2012
University of Michigan
2003
Phenylketonuria (PKU) is caused by a mutation in the phenylalanine (phe) hydroxylase gene and requires low-phe diet plus amino acid (AA) formula to prevent cognitive impairment. Glycomacropeptide (GMP) contains minimal phe provides palatable alternative AA formula. Our objective was compare growth, body composition, energy balance Pah(enu2) wild-type mice fed GMP, AA, or high-phe casein diets from 3-23 wk of age. The 2 × 3 design included main effects genotype, sex, diet. Fat lean mass were...
Pediatric trauma patients presenting to referring facilities (RF) often undergo computed tomography (CT) scans identify injuries before transfer a Level I pediatric center (PTC). The purpose of our study was evaluate RF compliance with the American College Radiology (ACR) guidelines minimize ionizing radiation exposure in and determine frequency additional or repeat CT imaging after PTC.After institutional review board approval, retrospective all admissions from January 2010 December 2011 at...
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Glucagon-like peptide-2 (GLP-2) is a nutrient-dependent, proglucagon-derived gut hormone that shows promise for the treatment of short bowel syndrome (SBS). Our objective was to investigate how combination GLP-2 + enteral nutrients (EN) affects intestinal adaption in rat model mimics severe human SBS and requires parenteral nutrition (PN). Male Sprague-Dawley rats were assigned one five groups maintained with PN 18 days: total (TPN) alone, TPN (100 μg·kg(-1)·day(-1)), EN GLP-2(7 days),...
Glucagon-like peptide-2 (GLP-2) action is dependent on intestinal expression of IGF-I, and IGF-I modulated by IGF binding proteins (IGFBP). Our objective was to evaluate whether the response GLP-2 or IGFBP-3 -5. Male, adult mice in six treatment groups, three wild-type (WT) double IGFBP-3/-5 knockout (KO), received twice daily intraperitoneal injections (0.5 μg/g body wt), (4 PBS (vehicle) for 7 days. KO showed a phenotype lower plasma concentration, but greater weight relative mass visceral...
Abstract Less than 50% of patients with higher-risk myelodysplastic syndromes (MDS) show clinical response to standard-of-care hypomethylating (HMA) therapy. Significant enthusiasm existed for immunotherapy/HMA combinations these patients, but studies have failed deliver on the initial promise. We demonstrated that MDS a deficiency in antigen-presenting cells, called CD141Hi dendritic cells (DC). DC-deficient reduced HMAs, worse overall survival, and less cancer vaccination. hypothesized...