A5007675071- Glaucoma and retinal disorders
- Retinal Diseases and Treatments
- Retinal Imaging and Analysis
- Ophthalmology and Eye Disorders
- Ocular Surface and Contact Lens
- Traumatic Brain Injury and Neurovascular Disturbances
- Proteoglycans and glycosaminoglycans research
- Cerebral Venous Sinus Thrombosis
- Optical Imaging and Spectroscopy Techniques
- melanin and skin pigmentation
- Retinal Development and Disorders
- Intraocular Surgery and Lenses
- Corneal surgery and disorders
- Retinal and Optic Conditions
- Ocular Oncology and Treatments
- Pharmacology and Obesity Treatment
- Parasitic Diseases Research and Treatment
- Hemodynamic Monitoring and Therapy
- Cell Adhesion Molecules Research
- Fungal Plant Pathogen Control
- Corneal Surgery and Treatments
- Retinal and Macular Surgery
- Plant Pathogens and Fungal Diseases
- Dermatological diseases and infestations
- Parasites and Host Interactions
University of Iceland
1998-2022
National University Hospital of Iceland
2009-2022
Reykjavík University
2009-2016
Durham University
2001
W.K. Kellogg Foundation
1999
University of Michigan
1999
Duke University
1997
Purpose.: To determine whether retinal vessel oxygen saturation is affected in primary open-angle glaucoma (POAG) patients. Methods.: Retinal patients with POAG was measured vessels a spectrophotometric oximeter darkness, and visual fields were obtained. Oxygen tension (Po 2) calculated from values. Statistical analysis performed using Pearson's correlation Student's t-test. Results.: Mean venules higher persons poor (68% ± 4%, mean SD) than those good (62% 3%; P = 0.0018). The arteriovenous...
<h3>AIMS/BACKGROUND</h3> Retinal vessel dilatation is a well known phenomenon in diabetes. In this study, the theory of whether excessive changes diameter and length retinal vessels occur development diabetic macular oedema was tested, supporting hypothesis that may be linked to hydrostatic pressure described Starling’s law. <h3>METHODS</h3> From fundus photographs patients attending regular eye screening programme, segment were measured three retinopathy groups (12 each) with (DMO),...
<h3>Background</h3> To test whether retinal oxygen metabolism is different in glaucoma patients compared with healthy subjects. <h3>Methods</h3> This was a two-centre study where vessel saturation measured and individuals non-invasive spectrophotometric oximeter. Visual fields were obtained the patients. <h3>Results</h3> No statistical difference found arterioles (p=0.16), venules (p=0.16) arteriovenous (p=0.24) when all (n=74) (n=89). When advanced (visual field mean defect (MD ≥ 10 dB,...
<h3>AIM</h3> To examine the distribution and clinical ophthalmic characteristics of pseudoexfoliation syndrome (pseudoexfoliation) glaucoma in Icelandic families. <h3>METHODS</h3> families containing three or more members aged 70 older with at least one member were indentified. All family over age 45 invited to participate. Visual acuity, Goldmann applanation tonometry, gonioscopy, slit lamp examination before after dilatation, dilated fundus performed on all available members. Pertinent...
To determine the concordance of glaucoma and ocular parameters in monozygotic twins their spouses.This was a prospective study that included 50 twin pairs 55 years age or older 47 spouses. Zygosity determined by genetic laboratory testing.The open-angle 98.0%, which significantly exceeded twin/spouse (70.2%). There significant association mean intraocular pressure (IOP), axial length, anterior chamber depth, refractive error pairs. However, there no between spouses for these parameters....
Purpose: To examine the importance of genetic factors in age-related macular degeneration by using a twin study to compare concordance monozygotic pairs and their spouses.Methods: This was prospective that included 50 47 spouses.Zygosity determined laboratory testing.Macular findings were graded based on grading system used Macular Photocoagulation Study Group International ARM Epidemiological Group.Results: The 90% which significantly exceeded twin/spouse (70.2%); pΩ0.0279.In nine...
Purpose.: Glaucoma may involve disturbances in retinal oxygenation and blood flow. The purpose of this study was to measure the effect glaucoma filtration surgery on vessel oxygen saturation. Methods.: A noninvasive spectrophotometric oximeter used hemoglobin saturation arterioles venules before after surgery. Twenty-five consecutive patients were recruited, 19 had adequate image quality. Fourteen underwent trabeculectomy five tube Twelve primary open-angle seven exfoliative glaucoma. IOP...
<h3>Aims:</h3> To examine whether the addition of dorzolamide to timolol monotherapy influences oxygen saturation in human retina. <h3>Methods:</h3> Non-invasive spectrophotometric retinal oximetry was used measure vessels. Twenty patients with open-angle glaucoma (11) and ocular hypertension (9) were recruited. The randomised into receiving or dorzolamide–timolol combination for an 8-month test period, followed by a second before which switched treatments. Oximetry measurements performed at...
Purpose: To test a new drug delivery platform with dorzolamide γ-cyclodextrin (γCD) nanoparticle eye drops for intraocular pressure (IOP) control and safety compare Trusopt.® Methods: Self-aggregating γCD containing 3% were given once day (QD) compared Trusopt three times (TID) in prospective randomized single masked crossover trial over 24 h. Seventeen subjects IOP 18 mmHg recruited. was measured an Icare Tonometer Pro.® Results: There no statistically significant difference the lowering...
<h3>Aim</h3> To examine the age- and gender-specific prevalent 5-year incident risk of developing exfoliation syndrome (XFS). <h3>Methods participants</h3> In a population-based random sample citizens 50 years older, 1045 persons had baseline examination in 1996; 846 958 survivors (88.2%) follow-up 2001. Following maximum dilatation pupils, diagnosis was established on slit-lamp examination. An extensive questionnaire administered at follow-up. Prevalent then calculated using multivariate...
To develop a Physicians' Guide to assist clinicians in the concomitant use of glaucoma and systemic medications.The records 100 consecutive patients with chronic open-angle were retrospectively studied determine most common medications that are prescribed this population. The ten drug classes then used construct guide potential interactions side effects when these concomitantly drugs.Eighty-four receiving 1 or more (a mean 3.5) for 2.6 conditions. Systemic antihypertensive agents was class...
Compare (a) nonmitomycin C (MMC) trabeculectomy and 1.5% dexamethasone nanoparticle (DexNP) eye drops postoperatively with (b) MMC Maxidex® postoperatively.Randomized prospective single masked clinical trial 20 patients primary open-angle glaucoma undergoing trabeculectomy. The study group consisted of 10 without intraoperatively postoperative DexNP drops, the control treated . were tapered out over 8 weeks. main outcome measures as follows: rates complete success, that is intraocular...
Abstract. A prospective double‐masked clinical trial was conducted to determine whether retrobulbar bupivacaine block had an effect on post‐operative pain, nausea and intra‐ use af analgesics in retinal detachment surgery performed under general anaesthesia. Thirty‐two patients were randomized have anaesthesia with or without bupivacaine. Pain score documented as 0–10 (0 = no pain. 10 worst pain ever felt). Post‐operative significantly lower the group during first hours than control group....
Visual field loss is a complication of vitrectomy and concern for patients with glaucoma. Our objective was to determine whether associated new defects in glaucoma.This retrospective case series involved 7 eyes patients, who had open-angle glaucoma underwent macular hole (2) or epiretinal membrane (5).Acuity improved by at least two lines 5 eyes. fields showed change mean deviation following (mean difference -1.50 dB, P=0.0006, paired Student's t-test). One eye confirmed progression...
Introduction Glaucoma is a degenerative disease in the optic nerve with associated visual field defects (VFD). Trabeculectomy most common glaucoma surgery. Surgery indicated if glaucomatous neuropathy progresses despite tolerated medical treatment or patients severe VFD. The purpose of this paper to describe severity damage undergoing their first trabeculectomy Iceland. Methods A retrospective review records all open angle that underwent at Landspitali University Hospital, from June 2013...
Purpose Mean retinal venous oxygen saturation (VSatO 2 ) has been found to be different from normal in several diseases. There are speculations that metabolic imaging of the retina could helpful monitoring such diseases and perhaps help with diagnosis. The aim study was characterize range VSatO further examine patients fall outside range. Methods Retinal vessel measured healthy individuals ( n = 89), glaucoma 78), retinitis pigmentosa (RP, 10), diabetic retinopathy (DR, 54) central vein...