A5073539143- Cardiovascular Function and Risk Factors
- Cardiovascular, Neuropeptides, and Oxidative Stress Research
- Endoplasmic Reticulum Stress and Disease
- Inflammasome and immune disorders
- Autophagy in Disease and Therapy
- Advanced Glycation End Products research
- MicroRNA in disease regulation
- Renin-Angiotensin System Studies
- Sustainable Agricultural Systems Analysis
- Heat Transfer and Optimization
- Spectroscopy and Chemometric Analyses
- Plant Water Relations and Carbon Dynamics
- Heat Transfer and Boiling Studies
- Agricultural Systems and Practices
- Environmental and Agricultural Sciences
- Adipose Tissue and Metabolism
- Ion Transport and Channel Regulation
- Plant Physiology and Cultivation Studies
- Pain Management and Treatment
- Cardiac tumors and thrombi
- Cardiovascular and Diving-Related Complications
- Neurological Disease Mechanisms and Treatments
- Heat Transfer Mechanisms
- S100 Proteins and Annexins
- interferon and immune responses
Yantaishan Hospital
2024-2025
Fujian Agriculture and Forestry University
2023-2024
Qiqihar University
2024
Chinese Academy of Medical Sciences & Peking Union Medical College
2024
Fujian Academy of Agricultural Sciences
2024
Hainan University
2023
Qilu Hospital of Shandong University
2014-2019
Canadian Cardiovascular Society
2015
National Natural Science Foundation of China
2015
Creative Commons
2015
Background Nucleotide-binding oligomerization domain-like receptor protein 3 (NLRP3) inflammasome is associated with metabolic disorder and cell death, which are important triggers in diabetic cardiomyopathy (DCM). We aimed to explore whether NLRP3 activation contributes DCM the mechanism involved. Methods Type 2 rat model was induced by high fat diet low dose streptozotocin. The characteristics of type were evaluated tests, echocardiography histopathology. Gene silencing therapy used...
Abstract Apoptosis is a key event involved in diabetic cardiomyopathy. The expression of high mobility group box 1 protein ( HMGB 1) up‐regulated mice. However, the molecular mechanism glucose HG )‐induced cardiomyocyte apoptosis remains obscure. We aimed to determine role ‐induced cardiomyocytes. Treating neonatal primary cardiomyocytes with increased cell apoptosis, which was accompanied by elevated levels 1. Inhibition short‐hairpin RNA significantly decreased reducing caspase‐3...
Colorectal cancer (CRC) displays a predilection for metastasis to liver. Although stromal cell-derived factor-1 (SDF-1)/CXCR4 plays an important role in the liver metastasis, molecular mechanism still remains obscure. We previously reported that integrin αvβ6 was implicated progression of CRC. However, no data are currently available on cross talk between CXCR4 and αvβ6. In present study, we first demonstrated their analyzed 159 human CRC samples found expression significantly associated...
Objective To systematically evaluate the efficacy and safety of butylphthalide combined with donepezil versus monotherapy for treatment vascular dementia. Methods Randomized controlled trials were searched in electronic databases, including PubMed, Embase, Cochrane Library, China National Knowledge Infrastructure, Chinese Science Technology Periodical Database (VIP), Wan Fang, Biology Medicine from inception to 29 November 2022. Two reviewers independently screened papers extracted data...
Growing evidence shows that protein kinase D (PKD) plays an important role in the development of pressure overload-induced cardiac hypertrophy.However, mechanisms involved are not clear.This study tested our hypothesis PKD might mediate hypertrophy by negatively regulating autophagy using technique knockdown siRNA.Cardiac was induced 8-week old male C57BL/6 mice transverse aortic constriction (TAC).TAC were then divided into five groups receiving treatments vehicle (DMSO), inducer rapamycin...
Abstract Bromodomain‐containing protein 7 (BRD7) is a tumour suppressor that known to regulate many pathological processes including cell growth, apoptosis and cycle. Endoplasmic reticulum (ER) stress‐induced plays key role in diabetic cardiomyopathy (DCM). However, the molecular mechanism of hyperglycaemia‐induced myocardial still unclear. We intended determine BRD7 high glucose (HG)‐induced cardiomyocytes. In vivo , we established type 1 rat model by injecting high‐dose streptozotocin...
As an important production factor of grain production, agricultural machinery can effectively provide a theoretical basis for modernization development strategies by exploring its impact on capacity and efficiency. This research starts from the two aspects efficiency, takes rice, wheat, corn as objects, uses C–D function Tobit model basis, respectively, to establish models At same time, according different emphases models, this designs variable systems finally data 2017 2021 empirical...
Drying is one of the best methods to preserve quality fresh fruits and prolong their shelf life. This study focuses on Prunus armeniaca L. cv. ‘Diaogan’ (commonly known as Diaogan apricot) sourced from Xinjiang, China explore impact two natural drying (shade open-air in rocky desert) kinetics, color, textural characteristics, microstructure, chemical properties, antioxidant capacity apricots. The experimental results indicate that throughout process, time required for desert was reduced by...
The dysregulated behavior of vascular smooth muscle cells (VSMCs) serves an important role in the pathogenesis cardiovascular diseases diabetes. present study aimed to investigate effects microRNA (miR)‑132 on proliferation and migration VSMCs under high glucose conditions mimic We observed that expression miR‑132 was significantly decreased E2F transcription factor 5 (E2F5) upregulated (HG)‑treated or those obtained from diabetic rats. A dual luciferase reporter gene assay revealed could...
Hypereosinophilic syndrome (HES), characterized by an increased number of eosinophils in tissues and/or blood, presents with heterogeneous clinical manifestations. Studies have shown that HES can affect the nervous system and may be associated cerebral infarction. Patent foramen ovale (PFO) is most common congenital intracardiac defect cause right-to-left shunting contribute to paradoxical embolization venous emboli, even lead stroke. We report case a young man who presented infarction...
The cortex-to-stele ratio (CSR), as it increases from thin- to thick-root species in angiosperms, is theorised effectively reflect a compensation for the ‘lag’ of absorption behind transportation. But still not known if this compensatory effect exists gymnosperm or governs root structure and function within species. Here, anatomical, morphological, tissue chemical traits absorptive roots were measured three temperate angiosperm Differences CSR above functional traits, well their...
The present study was designed to determine the role of PKD in vascular remodeling (VR) Spontaneously hypertensive rats (SHRs). Increased SBP, VR and activation were prominent SHRs. SBP has a positive correlation with ratio media lumen (MT/LD), volume fraction collagen (VFC), hydroxyproline, IL-6, TNF-α nitrotyrosine content significantly related activated PKD. It may be concluded that plays central VR, mechanism its regulation hypertrophy, fibrosis, inflammation oxidative stress.
With increased heat control requirements for high-heat-flux products in a narrow dissipation space, the ultra-thin micro-heat pipe (MHP) with high transfer performance has become an ideal component. In this study, computational fluid dynamics (CFD) method is used to conduct three-dimensional modeling based on geometric structure characteristics of MHP. The capillary pressure sintered wick represented by modified parameter, and simple valuable mass model MHP established fitting real...
Tetraspanin 1 (TSPAN1) is a newly discovered protein of the tetrameric family encoded by
This study focuses on the problem of corn yield prediction, and a novel prediction model based dynamic ensemble stacking regression algorithm is proposed. The aims to achieve more accurate in-depth exploration potential correlations in multisource multidimensional data. Data weather conditions, mechanization degree, maize Qiqihar City, Heilongjiang Province, from 1995 2022, are used. Important features determined extracted effectively by using principal component analysis indicator...