- Antibiotics Pharmacokinetics and Efficacy
- Food composition and properties
- Agriculture Sustainability and Environmental Impact
- Blood disorders and treatments
- Seed and Plant Biochemistry
- Pneumonia and Respiratory Infections
- Antibiotic Use and Resistance
- Antimicrobial Resistance in Staphylococcus
Universidad Nacional Agraria La Molina
2023
Hospital Luis Calvo Mackenna
2014-2021
The University of Queensland
2014
Morbidity and mortality for critically ill patients with infections remains a global healthcare problem. We aimed to determine whether β-lactam antibiotic dosing in achieves concentrations associated maximal activity affect patient outcome.This was prospective, multinational pharmacokinetic point-prevalence study including 8 antibiotics. Two blood samples were taken from each during single interval. The primary pharmacokinetic/pharmacodynamic targets free above the minimum inhibitory...
Background and aims: Children admitted to critical care units develops a SIRS that determines changes in pharmacokinetic pharmacodynamic (PK/PD) parameters. Monitoring PK/PD of vancomycin, should be complemented with other parameters (area under the curve over MIC (AUC)) optimize clinical microbiological outcome. Aims: To assess pharmacokinetics vancomycin children hospitalized PICU NICU, comparing traditional AUC. Methods: A prospective, descriptive study NICU. Patients received 40mg/kg/day...
BACKGROUND: The concern about consuming healthy foods has increased in recent years. Not only are they expected to comply with essential feeding functions, but also provide health benefits. Probiotics one of the main functional components be present and beverages. They many benefits stand out due their metabolic capacities adaptability different habitats. In addition, Quinoa seeds contain valuable quantities quality protein nutritional values carbohydrates, proteins, fats, fibers, mineral...
Aims & Objectives: Vancomycin is widely used in PICU The relationship between Plasma Trough Concentrations (PTC) with effectiveness and safety crucial. Area Under the Curve (AUC) >400 (mcg *h/mL) < 600 related to better therapeutic results.Our objetive was compare initiation dose of vancomycin: 40 mg / kg day (A) versus 60 (B). Methods: Prospective cohort study, we included all patients that received vancomycin at 2018 for least 48 hours PTC, AUC measurement, randomizing A or B doses....