- Hemodynamic Monitoring and Therapy
- Cardiac, Anesthesia and Surgical Outcomes
- Respiratory Support and Mechanisms
- COVID-19 Clinical Research Studies
- Cardiac Arrest and Resuscitation
- Ultrasound in Clinical Applications
- Cardiovascular Function and Risk Factors
- Sepsis Diagnosis and Treatment
- Airway Management and Intubation Techniques
- Long-Term Effects of COVID-19
- Mechanical Circulatory Support Devices
- Non-Invasive Vital Sign Monitoring
- Thermal Regulation in Medicine
- Abdominal Surgery and Complications
- Intensive Care Unit Cognitive Disorders
- Nosocomial Infections in ICU
- Pulmonary Hypertension Research and Treatments
- Atrial Fibrillation Management and Outcomes
- Appendicitis Diagnosis and Management
- Cardiac and Coronary Surgery Techniques
- Venomous Animal Envenomation and Studies
- Antibiotics Pharmacokinetics and Efficacy
- Cardiac Structural Anomalies and Repair
- Tracheal and airway disorders
- Pituitary Gland Disorders and Treatments
Centre Hospitalier Universitaire Amiens-Picardie
2016-2025
Université de Picardie Jules Verne
2015-2025
Simplification des soins chez les patients complexes
2018-2025
Mécanismes physiopathologiques et conséquences des calcifications cardiovasculaires
2018-2022
Physiopathologie et Epidémiologie des Maladies Respiratoires
2016-2022
RELX Group (United States)
2021
Inserm
2010-2018
CHU Dijon Bourgogne
2018
Imation (United States)
2007-2016
Centre Hospitalier Universitaire de Nîmes
2014
Morbidity and mortality for critically ill patients with infections remains a global healthcare problem. We aimed to determine whether β-lactam antibiotic dosing in achieves concentrations associated maximal activity affect patient outcome.This was prospective, multinational pharmacokinetic point-prevalence study including 8 antibiotics. Two blood samples were taken from each during single interval. The primary pharmacokinetic/pharmacodynamic targets free above the minimum inhibitory...
We have almost no information concerning the value of inferior vena cava (IVC) respiratory variations in spontaneously breathing ICU patients (SBP) to predict fluid responsiveness.SBP with clinical need were included prospectively study. Echocardiography and Doppler ultrasound used record aortic velocity-time integral (VTI), stroke volume (SV), cardiac output (CO) IVC collapsibility index (cIVC) ((maximum diameter (IVCmax)- minimum (IVCmin))/ IVCmax) at baseline, after a passive leg-raising...
To determine whether peak systolic velocity of tricuspid annular motion assessed by tissue Doppler echocardiography (Sta), a right ventricular function parameter, can discriminate patients with true- and false-positive pulse pressure variation. Pulse variation is used to predict fluid responsiveness in mechanically ventilated patients. However, this parameter has been reported be falsely positive, especially dysfunction.A prospective study.Medical surgical intensive care unit university...
The passive leg-raising maneuver is a reversible fluid-loading procedure used to predict fluid responsiveness in mechanically ventilated patients. aim of the present study was determine whether intra-abdominal hypertension (which impairs venous return) reduces ability leg raising detect critically ill patients.A prospective study.The medical and surgical intensive care unit university center.Forty-one patients with pulse pressure variation >12%.Stroke volume continuously monitored by...
Abstract Introduction Pulse pressure variation (PPV) has been shown to predict fluid responsiveness in ventilated intensive care unit (ICU) patients. The present study was aimed at assessing the diagnostic accuracy of PPV for prediction by using grey zone approach a large population. Methods pooled data 556 patients from nine French ICUs. Hemodynamic (PPV, central venous (CVP) and cardiac output) ventilator variables were recorded. Responders defined as increasing their stroke volume more...
Abstract Background: The effectiveness of simulation is rarely evaluated. aim this study was to assess the impact a short training course on ability anesthesiology residents comply with current difficult airway management guidelines. Methods: Twenty-seven third-year were assessed simulator in “can’t intubate, can’t ventilate” scenario before (the pretest) and then randomly 3, 6, or 12 months after posttest). built so that resident prompted perform cricothyrotomy. Compliance guidelines...
ObjectivesEnterococci may increase morbidity and mortality in elderly patients with intra-abdominal infections (IAIs) hospitalized the intensive care unit (ICU).
Abstract Hip fracture (HF) remains a main issue in the elderly patient. About 1.6 million patients year worldwide are victims of HF. Their incidence is expected to rise with aging world’s population. Identifying risk factors mandatory order reduce mortality and morbidity. The aim study was identify 1-year after HF surgery. We performed an observational, prospective, single-center at Amiens University Hospital (Amiens, France). After ethical approval, we consecutively included all who...
To describe the characteristics of patients hospitalized with COVID-19 (including their long-term at-home medication use), and compare them regard to course disease. assess association between renin-angiotensin system inhibitors (RASIs) disease progression critical outcomes.
Fluid challenge (FC) is one of the most common practices in Intensive Care Unit (ICU). The present study aimed to evaluate whether echocardiographic assessment response FC at end infusion or 20 min later could affect results FC.This a prospective, observational, multicenter including all ICU patients septic shock requiring 500 mL crystalloids over 10 min. responsiveness was defined as > 15% increase stroke volume (SV) assessed by velocity-time integral (VTI) measurements baseline (T0),...
Abstract Background The mortality rate for a patient with refractory cardiogenic shock on venoarterial (VA) extracorporeal membrane oxygenation (ECMO) remains high, and hyperoxia might worsen this prognosis. objective of the present study was to evaluate association between 28-day in setting. Methods We conducted retrospective bicenter two French academic centers. population comprised adult patients admitted shock. following arterial partial pressure oxygen (PaO 2 ) variables were recorded...
Excess exposure to norepinephrine can compromise microcirculation and organ function. We aimed assess the association between acute kidney injury (AKI) intensive care unit (ICU) mortality after cardiac surgery.This retrospective observational study included adult patients who underwent surgery under cardiopulmonary bypass from January 1, 2008, December 31, 2017, at Amiens University Hospital in France. The primary variable was postoperative during ICU stay endpoint presence of AKI. secondary...