A5101839383- Anesthesia and Pain Management
- Musculoskeletal pain and rehabilitation
- Pain Management and Opioid Use
- Pediatric Pain Management Techniques
- Cardiac, Anesthesia and Surgical Outcomes
- Pain Management and Treatment
- Spine and Intervertebral Disc Pathology
- Opioid Use Disorder Treatment
- Healthcare professionals’ stress and burnout
- Shoulder Injury and Treatment
- Veterinary Pharmacology and Anesthesia
- Treatment of Major Depression
- Sleep and Work-Related Fatigue
- Gut microbiota and health
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Enhanced Recovery After Surgery
- Family Caregiving in Mental Illness
- Family and Patient Care in Intensive Care Units
- Cell Image Analysis Techniques
- Vibrio bacteria research studies
- Hospital Admissions and Outcomes
- Pain Management and Placebo Effect
- Sports injuries and prevention
- Anesthesia and Neurotoxicity Research
- Meta-analysis and systematic reviews
Duke Medical Center
2019-2024
Duke University Hospital
2019-2023
Walter Reed National Military Medical Center
2012-2023
Duke University
2018-2023
Duke University Health System
2022
Oregon State University
2022
Defense & Veterans Center for Integrative Pain Management
2017
Uniformed Services University of the Health Sciences
2017
Naval Medical Center San Diego
2013
Vanderbilt University Medical Center
2013
Objective. The Defense and Veterans Pain Rating Scale (DVPRS 2.0) is a pain assessment tool that utilizes numerical rating scale enhanced by functional word descriptors, color coding, pictorial facial expressions matched to levels. Four supplemental questions measure how much interferes with usual activity sleep, affects mood contributes stress. Methods. Psychometric testing was performed on revised DVPRS 2.0 using data from 307 active duty service members experiencing acute or chronic pain....
Consensus indicates that a comprehensive, multimodal, holistic approach is foundational to the practice of acute pain medicine (APM), but lack uniform, evidence-based clinical pathways leads undesirable variability throughout U. S. healthcare systems. Acute studies are inconsistently synthesized guide educational programs. Advanced techniques involving regional anesthesia assume presence physician-led, multidisciplinary service, which often unavailable or applied. This heterogeneity and...
With the increasing societal awareness of prevalence and impact acute pain, there is a need to develop an pain classification system that both reflects contemporary mechanistic insights helps guide future research treatment. Existing classifications conditions are limiting, with predominant focus on sensory experience (e.g., intensity) pharmacologic consumption. Consequently, more broadly characterize classify multidimensional pain.Consensus report following expert panel involving Analgesic,...
Introduction We previously reported that a 6-day continuous peripheral nerve block reduces established postamputation phantom pain. To provide patients and providers with the information to best inform treatment decisions, here we reanalyze data present results in more patient-centered format. also on patient-defined clinically relevant benefits facilitate evaluation of available studies guide future trial design. Methods The original enrolled participants limb amputation pain who were...
Phantom limb pain is thought to be sustained by reentrant neural pathways, which provoke dysfunctional reorganization in the somatosensory cortex. We hypothesized that disrupting pathways with a 6-day-long continuous peripheral nerve block reduces phantom 4 weeks after treatment. enrolled patients who had an upper- or lower-limb amputation and established pain. Each was randomized receive 6-day perineural infusion of either ropivacaine normal saline. The primary outcome average severity as...
Fifty nine Division 1AA Scholarship football players served as subjects to assess performance, physical and personality factors, playing ability. Subjects were categorized according position also by high low strength levels, starters nonstarters, race. Player rank was determined independently for the first second team offensive coordinator, defensive conditioning coach. Coaches' rankings averaged data analysis. Each player ranked based on coaches' perception of his athletic ability...
In Brief BACKGROUND: Blockade of the saphenous nerve is often used for surgeries below knee. Depending on approach, success rates vary widely ranging from 33% to 88%. this prospective volunteer study, we compared 2 ultrasound-guided techniques, modified vastus medialis and perifemoral block with a knee field block. METHODS: Twenty adults, in single-blinded, crossover, trial underwent 3 different blocks. The primary end point was loss sensation distal two-thirds distribution nerve. Secondary...
Recent efforts to update the definitions and taxonomic structure of concepts related pain have revealed opportunities better quantify topics existing research subject areas.Here, we apply basic natural language processing (NLP) analyses on a corpus >200,000 abstracts published PubMed under medical heading (MeSH) "pain" topics, content, themes pain-related dating back 1940s.The most common stemmed terms included (601,122 occurrences), "patient" (508,064 "studi-" (208,839 occurrences)....
Abstract Objective To determine if the perioperative administration of valproic acid reduces incidence chronic pain three months after amputation or revision surgery. Design Multicenter, randomized, double-blind, placebo-controlled trial. Setting Academic, military, and veteran medical centers. Subjects One hundred twenty-eight patients undergoing surgery at Duke University Hospital, Walter Reed National Military Medical Center, Durham Veterans Affairs Center for either disease trauma....
Abstract Background Ongoing postoperative pain assessments are vital to optimizing management and attenuating the development of poor health outcomes after surgery. This study aimed characterize acute multidimensional trajectories impact on physical function, sleep, mood, stress examine clinical characteristics demographics associated with trajectory membership. Additionally, this compared levels intensity prescription opioid use at 2 weeks 1 month postoperatively across symptom...
In Brief Acute peripheral neuropathic pain after combat-related polytrauma is a common occurrence in the United States military that often refractory to current drugs and regional anesthesia. Both spinal cord nerve stimulation are successfully used for chronic states, but not reported acute pain. We present 2 cases of percutaneous ultrasound-guided sciatic placement soldiers who had conditions precluding them from placement. Opioid reduction marked increase functionality were possible one...
BACKGROUND: We recently reported that a 6-day continuous peripheral nerve block reduced established postamputation phantom pain 3 weeks after treatment ended. However, the immediate effects of perineural infusion (secondary outcomes) have yet to be reported. METHODS: Participants from 5 enrolling academic centers with an upper or lower limb amputation and received single-injection ropivacaine block(s) catheter insertion(s). They were subsequently randomized receive ambulatory either 0.5%...
A growing body of research has established that the microbiome can mediate dynamics and functional capacities diverse biological systems. Yet, we understand little about what governs response these microbial communities to host or environmental changes. Most efforts model microbiomes focus on defining relationships between microbiome, host, features within a specified study system therefore fail capture those may be evident across multiple In parallel with developments in research, computer...
Kent, Michael L. MD; Upp, Justin J. Buckenmaier, Chester C. III MD Author Information
Sleep disturbance is a modifiable risk factor that, when reduced, may improve subacute postsurgical outcomes (e.g., pain-related impact). Evidence also indicates that pain and sleep have bidirectional longitudinal relationship before to (sub) acutely after surgery. The objective of the present study examine degree which disturbances behavior uni- or relationships in sample patients undergoing sports orthopedic In this observational, cohort study, participants ( = 296) were adult (ages 18+)...
Abstract Objectives The National Institutes of Health Patient-Reported Outcomes Measurement Information System (PROMIS) is a multidimensional screening system evaluating biopsychosocial factors affecting pain and functioning. Using military sample, the current study 1) examined structure domains PROMIS, Defense Veterans Pain Rating Scale 2.0 (DVPRS), Catastrophizing (PCS) within presurgical setting 2) relationship these variables to pre- postsurgical opioid use. Methods This cross-sectional...
BACKGROUND: Pain trajectories have been described in numerous surgical settings where preoperative characteristics used to predict trajectory membership. Suboptimal pain intensity linked poor longitudinal outcomes. However, biopsychosocial modulators of postoperative may also distinct that inform additional targets improve recovery. METHODS: Patients undergoing total joint arthroplasty, thoracic surgery, spine major abdominal or mastectomy completed Patient Reported Outcome Measurement...
Objectives: Despite substantial research showing the bidrectional relationship between sleep and pain, there remains a dearth of examining role perioperative pain management interventions in mitigating postoperative disturbances. This secondary analysis prospective observational multisite study examined association peripheral nerve block (PNB) use during total knee or hip arthroplasty (TKA/THA) procedures outcomes. Materials Methods: Adult patients undergoing TKA THA were recruited from 2...