A5008874943- Cardiovascular Function and Risk Factors
- Thyroid Cancer Diagnosis and Treatment
- Asphalt Pavement Performance Evaluation
- Cardiac Imaging and Diagnostics
- Cardiovascular Health and Disease Prevention
- Grouting, Rheology, and Soil Mechanics
- Radiomics and Machine Learning in Medical Imaging
- Cardiovascular Disease and Adiposity
- Infrastructure Maintenance and Monitoring
- Ultrasound and Hyperthermia Applications
- Heart Rate Variability and Autonomic Control
- Cardiovascular Effects of Exercise
- Extracellular vesicles in disease
- Breast Lesions and Carcinomas
- Biomarkers in Disease Mechanisms
- Radiation Dose and Imaging
- Thyroid and Parathyroid Surgery
- Pulmonary Hypertension Research and Treatments
- Geotechnical Engineering and Analysis
- Breast Cancer Treatment Studies
- Geotechnical Engineering and Underground Structures
- Healthcare and Venom Research
- Transplantation: Methods and Outcomes
- Cardiomyopathy and Myosin Studies
- Geotechnical Engineering and Soil Stabilization
Harbin Medical University
2014-2025
Second Affiliated Hospital of Harbin Medical University
2014-2025
Chang'an University
2023-2024
Education Department of Heilongjiang Province
2024
Sichuan Highway Design and Research Institute
2022-2024
Abstract Aims Nicotine, a major component of tobacco, is an important factor contributing to atherosclerosis. However, the molecular mechanisms underlying link between nicotine and atherosclerosis are unclear. As extracellular vesicles (EVs) involved in intercellular communication atherosclerosis, we investigated whether their influence on arterial pathophysiology under stimulation. Methods results EVs from serum smokers (smoker-EVs) were significantly increased exacerbated endothelial...
Background/Aims: Intracellular calcium concentration ([Ca2+]i) homeostasis, an initial factor of cardiac hypertrophy, is regulated by the calcium-sensing receptor (CaSR) and associated with formation autolysosomes. The aim this study was to investigate role Calhex231, a CaSR inhibitor, on hypertrophic response via autophagy modulation. Methods: Cardiac hypertrophy induced transverse aortic constriction (TAC) in 40 male Wistar rats, while 10 rats underwent sham operation served as controls....
The application of warm mix asphalt (WMA) technology in polymer-modified becomes increasingly widespread, but it lacks thorough investigation on the interaction mechanism between additives and polymers. Accordingly, two new additives, an organic viscosity-reducing modifier (A) a surfactant-based (C), were selected to prepare SBS-modified asphalt. basic properties, viscosity-temperature characteristics, ageing resistance rheological properties modified tested. At last, modification was...
Soil stabilizer can improve the physical and chemical properties of clay bearing capacity subgrade soil. A kind liquid polymer soil vinyl acetate-ethylene was used in this paper. First all, effects content curing time on unconfined compressive strength (UCS) water stability were studied to clarify evolution stabilized Furthermore, pH test, Scanning Electron Microscopy (SEM), Energy Dispersive X-Ray Spectroscopy (EDS), Diffraction (XRD), Fourier Transform Infrared (FTIR) performed study...
Abstract Background Parathyroid glands are important endocrine glands, and the identification of normal parathyroid is crucial for their protection. The aim this study to explore sonographic characteristics analyze factors affecting display. Methods Seven hundred three subjects who underwent physical examination at our hospital were included. number, location, size, morphology, echogenicity blood flow distribution recorded. ultrasound display rate also summarized. Meanwhile, shear wave...
Pulmonary thromboembolism (PTE) is a common cause of cardiovascular death worldwide. Due to its nonspecific clinical symptoms, PTE easy be missed or misdiagnosed. transit time (PTT) noninvasive cardiopulmonary hemodynamic index, which the required for blood sample pass through pulmonary circulation. This study aim establish rabbit model using auto-thrombus, evaluating dynamic changes in rabbit's heart structure and function at multiple points before after modeling by echocardiography...
Despite significant advances in transplantation, acute cellular rejection (AR) remains a major obstacle that is most prevalent the first months post heart transplantation (HT). Current treatments require high doses of immunosuppressive drugs followed by maintenance therapies have systemic side effects including early infection. In this study, we attempted to prevent AR with myocardial-targeted galectin-7-siRNA delivery method using cationic microbubbles (CMBs) combined ultrasound targeted...
Adipose‑derived stem cells (ADSCs) and bone marrow‑derived (BMSCs) are considered to be prospective sources of mesenchymal stromal (MSCs), that can used in cell therapy for atherosclerosis. The present study investigated whether ADSCs co‑cultured with M1 foam macrophages via treatment oxidized low‑density lipoprotein (ox‑LDL) would lead similar or improved anti‑inflammatory effects compared BMSCs. ADSCs, peripheral blood monocytes, BMSCs ox‑LDL were isolated from ten coronary heart disease...
The emergence of STSW can reduce the amount materials such as sand and gravel improve its performance compared to conventional retaining walls. In order investigate key influencing factors STSW, compression modulus Scrap tire-soil module (STSM) was obtained by designing a full-scale strength test. shear through scale-test strength. On this basis, gravity established finite element numerical simulation software, bearing capacity analyzed. Further, were analyzed orthogonal tests, suggestions...
CD4+ T cells are activated during inflammatory dilated cardiomyopathy (iDCM) development to induce immunogenic responses that damage the myocardium. Low-intensity pulsed ultrasound (LIPUS), a novel physiotherapy for cardiovascular diseases, has recently been shown modulate responses. However, its efficacy in iDCM remains unknown. Here, we investigated whether LIPUS could improve severity of by orchestrating immune and explored therapeutic mechanisms.
Objectives To explore the efficacy of microwave ablation (MWA) in treatment benign thyroid nodules, and analyze related influencing factors.Methods The clinical ultrasound data 115 patients with nodules treated MWA were retrospectively analyzed. volume at 1, 3, 6, 12 months after procedure was obtained, reduction rate (VRR) each time point calculated. With VRR > 90% as criterion for nodule cure, binary logistic regression employed to screen factors that affect efficacy.Results ① At...
The aim of this study was to identify the ultrasound features and clinicopathological characteristics basal-like subtype triple negative breast cancers (TNBCs).This approved by ethical board Second Affiliated Hospital Harbin Medical University. patients' information available. 62 tumors from TNBC patients were interpreted. immunohistochemical results cytokertain5/6 (CK5/6) Epidermal Growth Factor Receptor (EGFR) used classify tumor into normal-like groups. association interpreted experienced...
An accurate diagnosis for high-suspicion nodules based on the 2015 American Thyroid Association (ATA) guidelines would reduce unnecessary invasive examinations. Elastography is a useful tool discriminating benign and malignant thyroid nodules. The aim of this study to investigate diagnostic efficiency elastography ATA in Chinese population.Thyroid with characteristics were subjected conventional ultrasound (US) strain (USE) examinations at 12 hospitals from 4 geographic regions across China....
Purpose: The aim of the study was to evaluate correlation ultrasound features with breast cancer molecular status. Materials and Methods: A retrospective review performed findings in 263 patients diagnosed invasive ductal carcinoma for comparison immunohistochemistric results were obtained from each lesion. Relationships between status investigated by using multiple regression analysis means stepwise logistic regression. Differences criteria assessed among women different Results: ER...
Myocardial ischemia-reperfusion injury (MIRI) is an important cause of early dysfunction and exacerbation immune rejection in transplanted hearts. The integrin-related protein CD47 exacerbates myocardial by inhibiting the nitric oxide signaling pathway through interaction with thrombospondin-1 (TSP-1). In addition, preservation quality donor hearts a key determinant transplant success. Preservation duration beyond four hours associated primary graft dysfunction. We hypothesized that blocking...
To evaluate the inter-observer variability and intra-observer repeatability of pulmonary transit time (PTT) measurement using contrast-enhanced ultrasound (CEUS) in healthy rabbits, assess effects dilution concentration contrast agents (UCAs) on PTT. Thirteen rabbits were selected, five concentrations UCAs 1:200, 1:100, 1:50, 1:10, 1:1 injected into right ear vein. Five digital loops obtained from apical 4-chamber view. Four sonographers PTT by plotting TIC atrium (RA) left (LA) at two...
Abstract Background Increasing evidence has been presented which suggests that left ventricular (LV) diastolic dysfunction may play an important role in the development of atrial fibrillation (AF). However, potential for LV to serve as a predictor AF recurrence after radiofrequency catheter ablation remains unresolved. Methods Dual Doppler and M-PW mode echocardiography were performed 67 patients with before 47 sinus rhythm. The parameters measured within identical cardiac cycles included,...
Heart failure (HF) is a serious end-stage condition of various heart diseases with increasing frequency. Few studies have combined clinical features high-throughput echocardiographic data to assess the risk major cardiovascular events (MACE) in patients failure. In this study, we assessed relationship between these factors and develop practical accurate prognostic dynamic nomogram model identify high-risk groups ultimately provide tailored treatment options. We conducted prospective study...