A5001372739- Cardiovascular Function and Risk Factors
- Soil erosion and sediment transport
- Hydrology and Sediment Transport Processes
- Cardiac Imaging and Diagnostics
- Aeolian processes and effects
- Thyroid Cancer Diagnosis and Treatment
- Landslides and related hazards
- Cardiovascular Disease and Adiposity
- Pulmonary Hypertension Research and Treatments
- Chemotherapy-induced cardiotoxicity and mitigation
- Radiomics and Machine Learning in Medical Imaging
- Ultrasound and Hyperthermia Applications
- Radiation Dose and Imaging
- Luminescence and Fluorescent Materials
- Extracellular vesicles in disease
- Hydrology and Watershed Management Studies
- Atherosclerosis and Cardiovascular Diseases
- Advanced Battery Materials and Technologies
- Cardiac electrophysiology and arrhythmias
- Tissue Engineering and Regenerative Medicine
- Circular RNAs in diseases
- Cardiac Fibrosis and Remodeling
- Advancements in Battery Materials
- Cardiovascular Health and Disease Prevention
- Ferroptosis and cancer prognosis
Second Affiliated Hospital of Harbin Medical University
2013-2024
Harbin Medical University
2013-2024
Northwest A&F University
2020-2024
Institute of Soil and Water Conservation
2021-2024
North University of China
2021-2022
Zhejiang Provincial People's Hospital
2021
Shanghai Sixth People's Hospital
2021
Shanghai Jiao Tong University
2021
Tumor Hospital of Xinjiang Medical University
2020
Xinjiang Medical University
2020
Abstract Doxorubicin-induced cardiotoxicity (DIC), which is a cardiovascular complication, has become the foremost determinant of decreased quality life and mortality among survivors malignant tumors, in addition to recurrence metastasis. The limited ability accurately predict occurrence severity doxorubicin-induced injury greatly hindered prevention DIC, but reducing dose mitigate side effects may compromise effective treatment primary malignancies. This posed longstanding clinical...
Abstract Aims Nicotine, a major component of tobacco, is an important factor contributing to atherosclerosis. However, the molecular mechanisms underlying link between nicotine and atherosclerosis are unclear. As extracellular vesicles (EVs) involved in intercellular communication atherosclerosis, we investigated whether their influence on arterial pathophysiology under stimulation. Methods results EVs from serum smokers (smoker-EVs) were significantly increased exacerbated endothelial...
The H-bond and ionic bond of the well-defined PSMA hydrolysates induce TSI-n–π carbonyl clusters to emit fluorescence RTP.
There are increasing concerns related to the cardiotoxicity of doxorubicin in clinical setting. Recently, melatonin has been shown exert a cardioprotective effect various cardiovascular diseases, including cardiotoxic conditions. In this study, we examined possible protective effects on doxorubicin-induced and explored underlying mechanisms process. We found that vitro treatment significantly decreased H9c2 cell viability induced apoptosis as manifested by increased TUNEL-positive cells,...
Abstract Aggregate disintegration is a critical process in soil splash erosion. However, the effect of organic carbon (SOC) and its fractions on aggregates still not clear. In this study, five soils with similar clay contents different SOC have been used. The effects slaking mechanical striking erosion were distinguished by using deionized water 95% ethanol as raindrops. simulated rainfall experiments carried out four heights (0.5, 1.0, 1.5 2.0 m). result indicated that aggregate stability...
Abstract Mounting evidence suggests that extracellular vesicles (EVs) are effective communicators in biological signalling cardiac physiology and pathology. However, the role of EVs injury, particularly ischemic myocardial scenarios, has not been fully elucidated. Here, we report acute infarction (AMI)‐induced can impair cardiomyocyte survival exacerbate injury. EV‐encapsulated miR‐503, which is enriched during early phase AMI, a critical molecule mediates Functional studies revealed miR‐503...
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The purpose of this study was to evaluate the value quantitative shear wave elastography (SWE) in indicating axillary lymph node metastasis (LNM) invasive breast cancers (IBCs) and investigate if S100A4 plays a key role promoting increasing stiffness IBC.The differences SWE 223 IBC patients were compared between LNM+ LNM- groups optimal cutoff values for diagnosing LNM calculated. We searched gene expression omnibus (GEO) determine whether more highly expressed IBCs that than those LNM-....
The significant role of multifunctional nanoprobes with complementary advantages in magnetic and near-infrared-II (NIR-II, 1000-1700 nm) fluorescence properties has been documented precision cancer theranostics. However, certain limitations, including the large size (>10 nm), low NIR-II quantum yield (QY < 1.0%), inefficient performance (relaxation rate 5.0 s-1 mM-1) nanoprobes, restrict their biomedical applications clinical translation. Albumin-based biomineralization was adopted to...
Abstract Myocardial infarction (MI) is a leading cause of death worldwide. Few drugs hold the ability to depress cardiac electrical and structural remodeling simultaneously after MI, which crucial for treatment MI. The aim this study investigate an effective therapy improve both heart caused by Here, “ion cocktail therapy” proposed reverse post‐MI in rats minipigs applying unique combination silicate, strontium (Sr) copper (Cu) ions due their specific regulatory effects on behavior key cells...
An accurate diagnosis for high-suspicion nodules based on the 2015 American Thyroid Association (ATA) guidelines would reduce unnecessary invasive examinations. Elastography is a useful tool discriminating benign and malignant thyroid nodules. The aim of this study to investigate diagnostic efficiency elastography ATA in Chinese population.Thyroid with characteristics were subjected conventional ultrasound (US) strain (USE) examinations at 12 hospitals from 4 geographic regions across China....
Abstract Background Cancer therapeutics–related cardiac dysfunction (CTRCD) from different chemotherapy strategies are underdetermined by echocardiography. As an imaging marker of subclinical dysfunction, two-dimensional speckle tracking echocardiography (2D-STE) may assist in identifying the impact patterns CTRCD. Methods A total 67 consecutive patients with invasive ductal breast carcinoma who will undertake neoadjuvant were enrolled and grouped according to their regimens based on biopsy...