Sai Xu

ORCID: 0000-0002-9078-3517
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About
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Research Areas
  • Hydrocarbon exploration and reservoir analysis
  • Hydraulic Fracturing and Reservoir Analysis
  • Enhanced Oil Recovery Techniques
  • High Entropy Alloys Studies
  • Advanced materials and composites
  • High-Temperature Coating Behaviors
  • Layered Double Hydroxides Synthesis and Applications
  • Advanced Photocatalysis Techniques
  • Electrocatalysts for Energy Conversion
  • Fuel Cells and Related Materials
  • Pancreatic function and diabetes
  • Additive Manufacturing Materials and Processes
  • Coal Properties and Utilization
  • Signaling Pathways in Disease
  • Welding Techniques and Residual Stresses
  • Advancements in Transdermal Drug Delivery
  • Polymer Surface Interaction Studies
  • Bee Products Chemical Analysis
  • Diabetes Treatment and Management
  • Diet, Metabolism, and Disease
  • Hydrogels: synthesis, properties, applications
  • Catalytic Processes in Materials Science
  • Regulation of Appetite and Obesity
  • NMR spectroscopy and applications
  • Nanoparticle-Based Drug Delivery

Dalian Maritime University
2025

Chinese PLA General Hospital
2023-2024

China University of Geosciences
2010-2023

Shandong University
2019-2023

Tianjin University
2019-2021

The First People's Hospital of Guiyang
2021

Second Hospital of Shandong University
2019

Tiangong University
2015

Beijing University of Chemical Technology
2012-2013

Nagoya University
2011-2013

Layered double hydroxides (LDHs) have aroused great attention as potential nanosized drug delivery carriers, but independent inorganic LDH wrapped with DNA shows very low transfection efficiency. To manipulate and control the surface properties of nanoparticles is crucial importance in designing LDH-based carriers. In this work, surface-initiated atom transfer radical polymerization (ATRP) 2-(dimethylamino)ethyl methacrylate (DMAEMA) employed to tailor functionality surfaces a...

10.1021/bc300683y article EN Bioconjugate Chemistry 2013-05-20

10.1016/j.jmatprotec.2021.117438 article EN Journal of Materials Processing Technology 2021-11-19

The selective two-electron oxygen reduction reaction (ORR) for H2O2 electrosynthesis provides a promising alternative to anthraquinone-based redox technology. However, atomically dispersed Co-N-C materials routinely lead the ORR process follow four-electron path via accessible Co-N4 moieties rather than terminating in competitive production. Herein, we demonstrate that by simultaneously reconstructing Co-N2-C and modifying functional groups into Co-adjacent carbon matrix through...

10.1021/acsami.4c14189 article EN ACS Applied Materials & Interfaces 2025-02-10

The ability to manipulate and control the surface properties of layered double hydroxide (LDH) nanoparticles is crucial importance in designing LDH-based carriers therapeutic agents. In this work, surface-initiated atom transfer radical polymerization (ATRP) zwitterionic 3-dimethyl(methacryloyloxyethyl) ammonium propane sulfonate (DMAPS) first employed tailor functionality LDH surfaces a well-controlled manner produce series well-defined hemocompatible hybrids (termed as LDHPS). blood...

10.1039/c2jm32720a article EN Journal of Materials Chemistry 2012-01-01

10.1016/j.jmatprotec.2021.117273 article EN Journal of Materials Processing Technology 2021-06-24

Permeability is usually considered to be related porosity. However, rocks with the same porosity may have different permeabilities in some cases, because of variations pore and throat size space connectivity. It vitally important understand effect on transport property. In this work, five sets regular network models six core-based are employed study permeability. Four kinds random distributions, i.e., uniform, normal, Weibull, log utilized generate size. Pore coordination number set two for...

10.3390/w14010077 article EN Water 2022-01-03

The annual number of human leukocyte antigen (HLA)-haploidentical allogeneic hematopoietic stem cell transplantation (haplo-HCT) is increasing steadily. Comparative studies about haplo-HCT versus HCT with HLA-matched sibling donors (MSD-HCT) have been tried in acute myeloid leukemia and B-cell lymphoblastic leukemia/lymphoma (ALL). Few were reported adult T-cell ALL (T-ALL). In this retrospective study, a total 88 consecutive patients T-ALL enrolled who underwent MSD-HCT ( n = 24) 64)...

10.1177/09636897241270401 article EN cc-by-nc Cell Transplantation 2024-01-01

Calcineurin-nuclear factor of activated T cells signaling controls the differentiation and function osteoclasts osteoblasts, regulator calcineurin-2 (Rcan2) is a physiological inhibitor this pathway. Rcan2 expression regulated by T(3), which also has central role in skeletal development bone turnover. To investigate maintenance, we characterized Rcan2(-/-) mice determined its T(3) receptor (TR) knockout thyroid-manipulated mice. had normal linear growth but displayed delayed intramembranous...

10.1210/en.2011-1814 article EN Endocrinology 2012-05-16

Microneedles are one promising penetration enhancement vehicle to overcome the stratum corneum skin barrier, which hampers of drug nanocrystals by transdermal delivery. In order clarify particle size effect on delivery, 60 nm, 120 and 480 nm curcumin were fabricated incorporated into dissolving hyaluronic acid polysaccharide microneedles. The microneedles showed good mechanical strength with 1.4 N/needle, possessing ability insert skin. passive permeation results that smaller diffused faster...

10.3390/ph15020206 article EN cc-by Pharmaceuticals 2022-02-08

Obesity is a serious international health problem that increases the risk of several diet-related chronic diseases. The genetic factors predisposing to obesity are little understood. Rcan2 was originally identified as thyroid hormone-responsive gene. In mouse, two splicing variants harbor distinct tissue-specific expression patterns have been identified: Rcan2-3 expressed predominately in brain, whereas Rcan2-1 brain and other tissues such heart skeletal muscle. Here, we show plays an...

10.1371/journal.pone.0014605 article EN cc-by PLoS ONE 2011-01-27

Adding acid to fracturing fluids is a promising method improve the stimulated reservoir volume of shale reservoirs. It great significance comprehensively understand pore structure change during acid–rock interaction for purpose maximizing its effects on long-term productivity enhancement. In this study, nanopore fractal dimension and surface two shales with different mineral compositions before after are determined from N2 adsorption results. Besides, micropore dimension, lacunarity,...

10.1021/acs.energyfuels.3c00693 article EN Energy & Fuels 2023-04-18

Summary Hydraulic fracturing to generate complex fracture networks is essential for shale reservoir development. However, the recovery of oil and gas still low due various engineering geological factors. Acid treatment has been approved as a potential approach enhance stimulated volume (SRV) by changing petrophysical mechanical properties. Understanding multiscale pore structure evolution behind macro-performance change critical in application acid reservoirs. In this study, cylindrical...

10.2118/212306-pa article EN SPE Journal 2022-10-12

A casting solution was prepared by dispersing titanium dioxide ( TiO 2 ) nanoparticles in the sodium alginate and acrylamide aqueous solution. The spread on a glass plate rod enlaced with brass wires to control thickness of sticky Then polyacrylamide/calcium alginate/ (PAM/CA/T) composite film obtained after UV irradiation cross-linking CaCl . PAM/CA/T characterized scanning electron microscope transmission microscope. had good strength toughness. And they did not rupture swelling 5 wt.%...

10.1142/s1793604715400147 article EN Functional Materials Letters 2015-02-06

Carbonate rocks are generally highly heterogeneous that make it difficult to accurately assess the behavior of fluid flow and transport in them. In this paper, we experimentally investigate oil–water displacement carbonate reservoirs by mimicking typical pore vugs carbonates through fabricating glass micromodels. The micromodels were saturated completely with oil, then water was injected continuously at a constant rate until steady state achieved. After that, injection increased steps. For...

10.1115/1.4043136 article EN Journal of Energy Resources Technology 2019-03-12

Background Osteoporosis affects the quality of life among middle-aged and elderly individuals. In addition, dysfunction osteoblasts can lead to progression osteoporosis. Circular (circ)RNAs are involved in various types diseases, including Moreover, it has been reported that hsa_circ_0001275 expression is upregulated However, effects on growth remain unclear. Methods present study, gene protein levels hFOB1.19 cells were detected via reverse transcription-quantitative (RT-qPCR) western blot...

10.1371/journal.pone.0252126 article EN cc-by PLoS ONE 2021-05-27
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