A5084244882- Nanoplatforms for cancer theranostics
- Dementia and Cognitive Impairment Research
- Alzheimer's disease research and treatments
- Nanoparticle-Based Drug Delivery
- RNA Interference and Gene Delivery
- Polymer Surface Interaction Studies
- Electrospun Nanofibers in Biomedical Applications
- Advanced biosensing and bioanalysis techniques
- Neurological Disease Mechanisms and Treatments
- Advanced Nanomaterials in Catalysis
- Wound Healing and Treatments
- Dendrimers and Hyperbranched Polymers
- Gold and Silver Nanoparticles Synthesis and Applications
- Luminescence and Fluorescent Materials
- Cardiovascular Health and Disease Prevention
- Hydrogels: synthesis, properties, applications
- Photoacoustic and Ultrasonic Imaging
- Cerebrovascular and Carotid Artery Diseases
- Photodynamic Therapy Research Studies
- Catalytic Processes in Materials Science
- Microfluidic and Capillary Electrophoresis Applications
- Catalysis and Oxidation Reactions
- Advanced Neuroimaging Techniques and Applications
- Graphene and Nanomaterials Applications
- Nutritional Studies and Diet
Qingdao University
2016-2025
Tsinghua University
2021-2025
Qingdao Municipal Hospital
2016-2025
Chongqing University of Arts and Sciences
2025
Zhejiang University of Technology
2024
Chongqing University of Science and Technology
2024
Zhejiang A & F University
2020-2023
Wuhan University of Science and Technology
2012-2023
Ningxia Normal University
2023
The First Affiliated Hospital, Sun Yat-sen University
2017-2022
Multimodal imaging-guided photothermal therapy (PTT), for the of cancer, based on a ferritin (FRT) nanocage loaded with near-infrared dye IR820 (designated DFRT) is demonstrated. The dual roles DFRT (in imaging and PTT) are successfully balanced by using two different excitation wavelengths: 550 nm high quantum-yield fluorescence one hand 808 photoacoustic PTT conversion efficiency other. As service to our authors readers, this journal provides supporting information supplied authors. Such...
Despite the effort of developing various nanodelivery systems, most them suffer from undesired high uptakes by reticuloendothelial system, such as liver and spleen. Herein we develop an endogenous phosphatase-triggered coassembly strategy to form tumor-specific indocyanine green (ICG)-doped nanofibers (5) for cancer theranostics. Based on coordinated intermolecular interactions, 5 significantly altered near-infrared absorbance ICG, which improves critical photoacoustic photothermal...
A versatile biomimetic theranostic agent based on magnetic melanin nanoparticles is developed for positron-emission tomography/magnetic resonance/photoacoustic/photothermal multimodal-imaging-guided cancer photothermal therapy and UV γ-irradiation protection. As a service to our authors readers, this journal provides supporting information supplied by the authors. Such materials are peer reviewed may be re-organized online delivery, but not copy-edited or typeset. Technical support issues...
Considering that hypoxia is closely associated with tumor proliferation, invasion, metastasis, and drug resistance, it of great significance to overcome in treatment. Herein, we report a hypoxia-induced specific photothermal therapy (PTT) based on the agent supramolecular perylene diimide radical anions. Hypoxic regions various tumors display strong reductive ability, such environments complex derivative cucurbit[7]uril could be reduced Benefiting from NIR absorption good conversion...
Abstract We report a cationic porphyrin 5,10,15,20‐tetrakis‐(4‐ N ‐methylpyridyl)‐porphyrin (TMPyP) that can respond to specific bacteria, followed by adaptable photodynamic/photothermal therapy processes. TMPyP could be reduced phlorin facultative anaerobes with strong reducing ability such as E. coli and S. typhimurium in hypoxic environments, possessing NIR absorption remarkable photothermal conversion capacity, thus demonstrating excellent antimicrobial activity (>99 %) therapy. While...
A photoresponsive drug delivery system was developed for light-mediated release and aptamer-targeted cancer therapy.
Carbon nanotubes have excellent penetrability and encapsulation efficiency in the fields of drug gene delivery. Because their physicochemical properties, biocompatible rodlike cellulose nanocrystals (CNCs) were reportedly expected to replace carbon nanotubes. In this work, CNCs from natural cotton wool functionalized with disulfide bond-linked poly(2-(dimethylamino)ethyl methacrylate) (PDMAEMA) brushes for effective biomedical applications. A range CNC-graft-PDMAEMA vectors (termed as...
The bioreducible star-shaped gene vector (POSS-(SS-PDMAEMA)8) with well-defined structure and relatively narrow molecular weight distribution was synthesized via atom transfer radical polymerization (ATRP) of (2-dimethylamino)ethyl methacrylate (DMAEMA) from a polyhedral oligomeric silsesquioxane (POSS) macroinitiator. POSS-(SS-PDMAEMA)8 composed biocompatible POSS core eight disulfide-linked PDMAEMA arms, wherein the chain length could be adjusted by controlling time. can effectively bind...
Abstract Construction of delivery systems for anticancer gold complexes to decrease their toxicity while maintaining efficacy is a key strategy optimize and develop medicines. Herein, we describe cancer‐targeted mesoporous silica nanoparticles (MSN) gold(III) porphyrin complex (Au‐1 a@MSN(R)) enhance its selectivity between cancer normal cells. Encapsulation Au‐1 within amplifies inhibitory effects on thioredoxin reductase (TrxR), resulting in loss redox balance overproduction reactive...
We report a supramolecular naphthalene diimide (NDI) radical anion with efficient NIR-II photothermal conversion for E. coli-responsive therapy. The (NDI-2CB[7])⋅- , which is obtained from the coli-induced in situ reduction of NDI-2CB[7] neutral complex, formed by host-guest interaction between an NDI derivative and cucurbit[7]uril (CB[7]), exhibits unexpectedly strong absorption remarkable capacity aqueous solution. caused self-assembly anions to form dimer radicals solution, supported...