A5102021510- Nanoplatforms for cancer theranostics
- Quantum Dots Synthesis And Properties
- Advanced biosensing and bioanalysis techniques
- Crystallization and Solubility Studies
- X-ray Diffraction in Crystallography
- Chalcogenide Semiconductor Thin Films
- Biosensors and Analytical Detection
- Luminescence Properties of Advanced Materials
- Advanced Sensor and Energy Harvesting Materials
- Photoacoustic and Ultrasonic Imaging
- Perovskite Materials and Applications
- Supercapacitor Materials and Fabrication
- Conducting polymers and applications
- Luminescence and Fluorescent Materials
- Advanced Nanomaterials in Catalysis
- Gold and Silver Nanoparticles Synthesis and Applications
- Polymer Foaming and Composites
- Advanced Semiconductor Detectors and Materials
- MicroRNA in disease regulation
- Advanced Biosensing Techniques and Applications
- biodegradable polymer synthesis and properties
- Cancer-related molecular mechanisms research
- Semiconductor Quantum Structures and Devices
- Carbon dioxide utilization in catalysis
- Advanced Photocatalysis Techniques
Xuzhou Medical College
2022-2025
Shanghai Jiao Tong University
2016-2025
Second Hospital of Anhui Medical University
2021-2025
Anhui Medical University
2021-2025
Third Xiangya Hospital
2019-2025
Zhongyuan University of Technology
2021-2024
Henan Normal University
2019-2024
Henan University
2017-2024
Peking University
2008-2024
Ningbo Institute of Industrial Technology
2021-2023
Abstract The hierarchical assembly of gold nanoparticles (GNPs) allows the localized surface plasmon resonance peaks to be engineered near‐infrared (NIR) region for enhanced photothermal therapy (PTT). Herein we report a novel theranostic platform based on biodegradable plasmonic nanovesicles photoacoustic (PA) imaging and PTT. disulfide bond at terminus PEG‐ b ‐PCL block‐copolymer graft enables dense packing GNPs during process induces ultrastrong coupling between adjacent GNPs. strong NIR...
A multifunctional theranostic platform based on photosensitizer-loaded plasmonic vesicular assemblies of gold nanoparticles (GNPs) is developed for effective cancer imaging and treatment. The vesicles (GVs) composed a monolayer assembled GNPs show strong absorbance in the near-infrared (NIR) range 650-800 nm, as result coupling effect between neighboring membranes. NIR absorption capability encapsulating photosensitizer Ce6 GVs enable trimodality fluorescence/thermal/photoacoustic...
Abstract We report a supramolecular strategy to prepare conductive hydrogels with outstanding mechanical and electrochemical properties, which are utilized for flexible solid‐state supercapacitors (SCs) high performance. The assembly of polyaniline polyvinyl alcohol through dynamic boronate bond yields the polyaniline–polyvinyl hydrogel (PPH), shows remarkable tensile strength (5.3 MPa) capacitance (928 F g −1 ). supercapacitor based on PPH provides large (306 mF cm −2 153 ) energy density...
Multifunctional nanomaterials with integrated diagnostic and therapeutic functions, combination therapy to enhance treatment efficacy, as well low toxicity have drawn tremendous attentions. Herein, we report a multifunctional theranostic agent based on peptide (LyP-1)-labeled ultrasmall semimetal nanoparticles of bismuth (Bi-LyP-1 NPs). Ultrasmall Bi NPs (3.6 nm) were facilely synthesized using oleylamine the reducing exhibited higher tumor accumulation after being conjugated tumor-homing...
Multimodal imaging-guided photothermal therapy (PTT), for the of cancer, based on a ferritin (FRT) nanocage loaded with near-infrared dye IR820 (designated DFRT) is demonstrated. The dual roles DFRT (in imaging and PTT) are successfully balanced by using two different excitation wavelengths: 550 nm high quantum-yield fluorescence one hand 808 photoacoustic PTT conversion efficiency other. As service to our authors readers, this journal provides supporting information supplied authors. Such...
YTH N6-methyladenosine (m6A) RNA binding protein 1 (YTHDF1) is a core factor in methylation modification. Recent studies have shown that m6A closely related to multiple tumors, thus YTHDF1 may also play role tumorigenesis. This study, aimed explore the of colorectal cancer (CRC). In this we identified as being highly expressed at mRNA and levels TCGA, GEO CRC primary CRC. Furthermore, gene copy number was positively correlated with expression Knocking down significantly inhibited cell's...
A white-light-emitting diode (white LED) with good color rendering index is fabricated based on a blue LED combined high-fluorescence CdS:Cu/ZnS quantum dots (QDs) and YAG:Ce phosphors. The reabsorption problem overcome by the excellent optical properties enlarged Stokes shift of QDs low absorption light wavelengths longer than 470 nm.
We present a novel gold bellflower (GBF) platform with multiple-branched petals, prepared by liquid–liquid–gas triphase interface system, for photoacoustic imaging (PAI)-guided photothermal therapy (PTT). Upon near-infrared (NIR) laser irradiation, the GBFs, strong NIR absorption, showed very PA response and an ultrahigh conversion efficiency (η, ∼74%) among reported agents. The excellent performance in PAI PTT is mainly attributed to unique features of GBFs: (i) petals enhanced local...
Abstract Flexible conductive materials with intrinsic structural characteristics are currently in the spotlight of both fundamental science and advanced technological applications due to their functional preponderances such as remarkable conductivity, excellent mechanical properties, tunable physical chemical so on. Typically, hydrogel fibers (CHFs) promising candidates owing unique including light weight, high length‐to‐diameter ratio, deformability, Herein, a comprehensive overview...
Abstract The hierarchical assembly of gold nanoparticles (GNPs) allows the localized surface plasmon resonance peaks to be engineered near‐infrared (NIR) region for enhanced photothermal therapy (PTT). Herein we report a novel theranostic platform based on biodegradable plasmonic nanovesicles photoacoustic (PA) imaging and PTT. disulfide bond at terminus PEG‐ b ‐PCL block‐copolymer graft enables dense packing GNPs during process induces ultrastrong coupling between adjacent GNPs. strong NIR...
Highly-fluorescent CdSe/CdS/ZnS core/multi-shell quantum dot (QD) nanophosphors were successfully synthesized via a phosphine-free and continual precursor injection method in paraffin liquid for the first time. The as-prepared cubic zinc blended QDs showed high photoluminescent yield (PLQY) excellent optical stability. We also fabricated QDs/epoxy composites by directly dispersing into epoxy resin as encapsulating light conversion materials application on white LED, possessed even better...
The presence of Fusobacterium nucleatum (F. nucleatum) in colorectal carcinoma tissue has been associated with microsatellite instability (MSI), lower-level T-cell infiltrates, and poor clinical outcomes. Considering differences the tumor-immune microenvironment between MSI-high non-MSI-high carcinomas, we hypothesized that association F. immune response might differ by tumor MSI status. Using samples from 1,041 rectal colon cancer patients within Nurses' Health Study Professionals Follow-up...
Abstract We report a supramolecular strategy to prepare conductive hydrogels with outstanding mechanical and electrochemical properties, which are utilized for flexible solid‐state supercapacitors (SCs) high performance. The assembly of polyaniline polyvinyl alcohol through dynamic boronate bond yields the polyaniline–polyvinyl hydrogel (PPH), shows remarkable tensile strength (5.3 MPa) capacitance (928 F g −1 ). supercapacitor based on PPH provides large (306 mF cm −2 153 ) energy density...
We report that a postsynthesis physical process (freeze–thaw cycles) can reform the microstructure of conductive polymer hydrogels from clustered nanoparticles to interconnected nanosheets, leading enhanced mechanical and electrochemical properties. The polyaniline–poly(vinyl alcohol) hydrogel after five freeze–thaw cycles (PPH-5) showed remarkable tensile strength (16.3 MPa), large elongation at break (407%), high capacitance (1053 F·g–1). flexible supercapacitor based on PPH-5 provided...
Abstract The use of X‐rays instead UV/Vis light to trigger photodynamic therapy, named X‐ray inducible holds tremendous promise due a high penetration capacity in tissues and is worthy in‐depth study. In this study, novel multifunctional nanoagent based on Merocyanine 540‐coupled Gd 2 (WO 4 ) 3 :Tb nanoscintillators the vitalization its abilities for dual‐modal computed tomography magnetic‐resonance‐imaging‐guided synergistic radio‐/X‐ray therapy tumors reported. Synergistic therapies show...