A5029091960- Nanoplatforms for cancer theranostics
- Nanoparticles: synthesis and applications
- Computational Drug Discovery Methods
- Organic Electronics and Photovoltaics
- Biodiesel Production and Applications
- Machine Learning in Materials Science
- Environmental Toxicology and Ecotoxicology
- Photodynamic Therapy Research Studies
- Analytical chemistry methods development
- Conducting polymers and applications
- Zebrafish Biomedical Research Applications
- Heavy Metal Exposure and Toxicity
- Luminescence Properties of Advanced Materials
- Advanced Photocatalysis Techniques
- Nanoparticle-Based Drug Delivery
- Algal biology and biofuel production
- Electromagnetic wave absorption materials
- Cardiac, Anesthesia and Surgical Outcomes
- Mass Spectrometry Techniques and Applications
- Water Quality and Pollution Assessment
- Protein Interaction Studies and Fluorescence Analysis
- Anesthesia and Pain Management
- Neuroendocrine regulation and behavior
- Head and Neck Surgical Oncology
- Environmental and Analytical Chemistry Studies
Xinjiang University
2022-2025
Institute of Molecular Physics of the Polish Academy of Sciences
2024
Polish Academy of Sciences
2024
Grantham and District Hospital
2023
United Lincolnshire Hospitals NHS Trust
2023
Nanjing University
2020-2022
Government Medical College
2016-2022
Collaborative Innovation Center of Advanced Microstructures
2022
Allama Iqbal Medical College
2022
Jinnah Postgraduate Medical Center
2022
Zebrafish embryos and early larvae are becoming increasingly important as models in biomedical research because of their low cost, high throughput potential a replacement for adult, higher vertebrate model species.The functional domains drug targets, other functionally proteins, often highly conserved between the zebrafish mammals.Furthermore, embryo or larva shows complex behavioural repertoire only few days after fertilization.Here, we show how studies mammals being translated to...
Abstract A general approach is proposed that allows for quantifying the relative toxic contribution of ions released from metallic nanoparticles and particles themselves, as exemplified case differently shaped zinc oxide (ZnO) (NPs) exposed to zebrafish embryos. First all, toxicity suspensions ZnO (NP (total) )—nanospheres, nanosticks, cuboidal submicron (SMPs), Zn(NO 3 ) 2 —to embryos was assessed. The observed NP assumed result combined effect present in (particle) dissolved Zn 2+ (ion) )....
Abstract The use of X‐rays instead UV/Vis light to trigger photodynamic therapy, named X‐ray inducible holds tremendous promise due a high penetration capacity in tissues and is worthy in‐depth study. In this study, novel multifunctional nanoagent based on Merocyanine 540‐coupled Gd 2 (WO 4 ) 3 :Tb nanoscintillators the vitalization its abilities for dual‐modal computed tomography magnetic‐resonance‐imaging‐guided synergistic radio‐/X‐ray therapy tumors reported. Synergistic therapies show...
Radio- and photodynamic therapies are the first line of cancer treatments but suffer from poor light penetration less radiation accumulation in soft tissues with high toxicity. Therefore, a multifunctional nanoplatform diagnosis-assisted synergistic radio- therapy tools facilitating early prognosis urgently needed to fight war against cancer. Further, integrating untargeted metabolomic analysis would collectively offer clinical pertinence through diagnosis prognosis. Here, we enriched...
Designing molecules for drugs has been a hot topic many decades. However, it is hard and expensive to find new molecule. Thus, the cost of final drug also increased. Machine learning can provide fastest way predict biological activity druglike molecules. In present work, machine models are trained prediction aromatase inhibitors. Data was collected from literature. Molecular descriptors calculated be used as independent features model training. The results showed that R2 values linear...
Designing of molecules for drugs is important topic from many decades. The search new very hard, and it expensive process. Computer assisted framework can provide the fastest way to design screen drug-like compounds. In present work, a multidimensional approach introduced designing screening antioxidant Antioxidants play crucial role in ensuring that body's oxidizing reducing species are kept proper balance, minimizing oxidative stress. Machine learning models used predict activity. Three...
In this research paper, we have reported solvent effects on nonlinear optical properties of tetrammineruthenium(II) complexes modified 1,10-phenanthrolines. Polarizability and hyperpolarizability were calculated in the gas phase, benzene (ε = 2.3), THF 7.52), dichloromethane 8.93), acetone 21.01), methanol 33.00), acetonitrile 36.64), water 80.10) using density functional theory. These solvents cover a wide range polarities. The results theoretical investigation shown that significantly...
Abstract Three sizes of copper nanoparticles (Cu NPs; 25 nm, 50 and 100 nm), 1 submicron‐sized particle, Cu(NO 3 ) 2 were added to the culture buffer zebrafish embryos from 24 h postfertilization 120 postfertilization. In suspensions Cu NPs main contribution toxicity was particle form particles NP , >71%) rather than dissolved ion ). All tested as well nitrate inhibited hatching, altered behavioral responses, increased incidence malformations. Different kinds abnormalities observed in...
The current study describes the emphatic use of response surface methodology for optimized biodiesel production using chemical and enzymatic transesterification rice bran sunflower oils. Optimal yields were determined to be 65.3 ± 2.0%, 73.4 3.5%, 96.5 1.6%, 89.3 2.0% 41.7 3.9% oil 65.6 1.2%, 82.1 1.7%, 92.5 2.8%, 72.6 1.6% 50.4 2.5% via catalyzed by NaOH, KOH NaOCH3,NOVOZYME-435 A.n. Lipase, respectively. Based upon analysis variance (ANOVA) Response Surface plots significant impact...
Nanoparticles (NPs) are extensively being used in modern nano-based therapies and nano-protein formulations.