A5001159243- SARS-CoV-2 and COVID-19 Research
- Extracellular vesicles in disease
- Viral gastroenteritis research and epidemiology
- COVID-19 Clinical Research Studies
- Mesenchymal stem cell research
- Acute Kidney Injury Research
- Periodontal Regeneration and Treatments
- Surgical Simulation and Training
- Cerebrospinal fluid and hydrocephalus
- Surgical Sutures and Adhesives
- Traumatic Brain Injury and Neurovascular Disturbances
- Electrospun Nanofibers in Biomedical Applications
- Fuel Cells and Related Materials
- Reconstructive Surgery and Microvascular Techniques
- Influenza Virus Research Studies
- Innovative Microfluidic and Catalytic Techniques Innovation
- Dialysis and Renal Disease Management
- Tissue Engineering and Regenerative Medicine
- Bone Tissue Engineering Materials
- Advanced Sensor and Energy Harvesting Materials
Hacettepe University
2021-2025
Selçuk University
2021
Vaccines that incorporate multiple SARS-CoV-2 antigens can further broaden the breadth of virus-specific cellular and humoral immunity. This study describes development immunogenicity VLP vaccine incorporates four structural proteins SARS-CoV-2.VLPs were generated in transiently transfected HEK293 cells, purified by multimodal chromatography, characterized tunable-resistive pulse sensing, AFM, SEM, TEM. Immunoblotting studies verified protein identities VLPs. Cellular immune responses...
Abstract Angiogenesis in injured tendons may contribute to regeneration, but quantifying it post‐injury has been mostly limited 2D semi‐quantitative histology. This study aimed develop micro‐CT as a 3D tool quantitatively assess tendon blood vessels an experimental animal model. Adult male Wistar rats ( N = 36) had injuries induced their Achilles by needle insertion. The included three groups: 12 hours (12H), 3 weeks (3W), and 8 (8W). uninjured left served the control for each group....
Acute hypoxic proximal tubule (PT) injury and subsequent maladaptive repair present high mortality increased risk of acute kidney (AKI) - chronic disease (CKD) transition. Human bone marrow mesenchymal stem cell-derived exosomes (hBMMSC-Exos) as potential cell therapeutics can be translated into clinics if drawbacks on safety efficacy are clarified. Here, we determined the real-time effective dose treatment window allogeneic hBMMSC-Exos, evaluated their performance structural functional...
Various techniques have been described for performing microsurgical anastomosis with providing high patency rates. Although the total anastomotic time may not be an issue when dealing a single set of anastomoses, using faster technique save significant amount in cases transferring flaps shorter critical ischemia or where multiple anastomoses are required. This study compares between four different combinations commonly used suturing and knot tying techniques.Twenty-four rats were divided...
Background Vaccines that incorporate multiple SARS-CoV-2 antigens can further broaden the breadth of virus-specific cellular and humoral immunity. This study describes development immunogenicity VLP vaccine incorporates 4 structural proteins SARS-CoV-2. Methods VLPs were generated in transiently transfected HEK293 cells, purified by multimodal chromatography characterized tunable resistive pulse sensing, AFM, SEM, TEM. Immunoblotting studies verified protein identities VLPs. Cellular immune...
Background Vaccines that incorporate multiple SARS-CoV-2 antigens can further broaden the breadth of virus-specific cellular and humoral immunity. This study describes development immunogenicity VLP vaccine incorporates 4 structural proteins SARS-CoV-2. Methods VLPs were generated in transiently transfected HEK293 cells, purified by multimodal chromatography characterized tunable resistive pulse sensing, AFM, SEM, TEM. Immunoblotting studies verified protein identities VLPs. Cellular immune...
Advances in bone tissue engineering through integrating biologically active extracellular nanovesicles with biomaterial platforms offer a promising solution to overcome the reduced residual volume and provide an efficient regeneration. Within scope of clinical research field regenerative medicine, this work represents potential human periodontal ligament fibroblasts (hPDLFs)-derived exosomes (hPDLFs-Exo) as cell-free therapy tool repair calvarial damage by utilizing their cell-instructive...