Iván López-Gónzalez

ORCID: 0000-0002-9147-6770
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About
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Research Areas
  • 3D Printing in Biomedical Research
  • Bone Tissue Engineering Materials
  • Electrospun Nanofibers in Biomedical Applications
  • Silk-based biomaterials and applications
  • Biodiesel Production and Applications
  • Graphene and Nanomaterials Applications
  • Bacterial biofilms and quorum sensing
  • Orthopedic Infections and Treatments
  • Dental Implant Techniques and Outcomes
  • Polymer Surface Interaction Studies
  • biodegradable polymer synthesis and properties
  • Cancer Cells and Metastasis
  • Hybrid Renewable Energy Systems
  • Photochromic and Fluorescence Chemistry
  • Algal biology and biofuel production
  • RNA Interference and Gene Delivery
  • Dental materials and restorations
  • Nanoplatforms for cancer theranostics
  • Microplastics and Plastic Pollution
  • Wound Healing and Treatments
  • Antimicrobial Peptides and Activities
  • Nanocomposite Films for Food Packaging

Universidad Autónoma del Estado de Hidalgo
2024

Universidad Católica San Antonio de Murcia
2019-2023

Tissue Regeneration Systems (United States)
2023

The fabrication of bioartificial tissue substitutes is a complex process that relies on the application innovative biomaterials and manufacturing techniques enabling generation cell-laden scaffolds mimicking natural interfaces. Among many biomaterials, gelatin methacryloyl (GelMA) hydrogels have shown great potential for 3D bioprinting-based engineering due to their high biocompatibility, biodegradability tuneable mechanical properties. In this study, use hybrid based GelMA highly purified...

10.36922/ijb.7888 article EN International Journal of Bioprinting 2025-02-06

Polyvinyl alcohol (PVA) hydrogels are well-known biomimetic 3D systems for mammalian cell cultures to mimic native tissues. Recently, several biomolecules were intended use in PVA improve their biological properties. However, retinol, an important biomolecule, has not been combined with a hydrogel culturing bone marrow mesenchymal stem (BMMS) cells. Thus, the first time, effect of retinol on physicochemical, antimicrobial, and proliferative properties was investigated. The ability protein...

10.3390/ijms232415623 article EN International Journal of Molecular Sciences 2022-12-09

Acute and chronic bone infections, especially those caused by methicillin-resistant Staphylococcus aureus (MRSA), remains a major complication therapeutic challenge. It is documented that local administration of vancomycin offers better results than the usual routes (e.g., intravenous) when ischemic areas are present. In this work, we evaluate antimicrobial efficacy against S. epidermidis novel hybrid 3D-printed scaffold based on polycaprolactone (PCL) chitosan (CS) hydrogel loaded with...

10.3390/pharmaceutics15061763 article EN cc-by Pharmaceutics 2023-06-18

In this work, we evaluated the influence of a novel hybrid 3D-printed porous composite scaffold based on poly(ε-caprolactone) (PCL) and β-tricalcium phosphate (β-TCP) microparticles in process adhesion, proliferation, osteoblastic differentiation multipotent adult human bone marrow mesenchymal stem cells (ah-BM-MSCs) cultured under basal osteogenic conditions. The vitro biological response ah-BM-MSCs seeded scaffolds was terms cytotoxicity, proliferation (AlamarBlue Assay®) after 1, 3, 7, 14...

10.3390/ijms222011216 article EN International Journal of Molecular Sciences 2021-10-18

Acute and chronic bone infections, especially those caused by methicillin-resistant Staphylococcus aureus (MRSA), remains a major complication therapeutic challenge. It is documented that local administration of vancomycin offers better results than the usual routes (e.g. intravenous) when ischemic areas are present. In this work, we evaluate antimicrobial efficacy against S. epidermidis analyzed potential cytotoxic effect novel hybrid 3D-printed scaffold based on poly(caprolactone) chitosan...

10.20944/preprints202305.0650.v1 preprint EN 2023-05-09

This work aims to provide an effective and novel dual tool for the biodistribution studies of biopolimeric nanoparticles by using modified silk fibroin as a model. is indispensable step in evaluation applicability biopolymeric drug delivery systems. In this work, we report new facile method radiolabeling conjugated chelating agent diethylenetriamine pentaacetic acid tagged with fluorescein isothiocyanate. Nanoparticles were characterized means dynamic light scattering, scanning electron...

10.1021/acsbiomaterials.0c00247 article EN ACS Biomaterials Science & Engineering 2020-04-23

Calcium phosphate materials are widely used as bone substitutes due to their bioactive and biodegradable properties. Also, the presence of silicon in composition seems improve bioactivity implant promote tissue repair. The aim this study was develop a novel ceramic scaffold by partial solid-state sintering method with lying field Nurse’s A-phase–silicocarnotite, tricalcium phosphate–dicalcium silicate (TCP–C2S) binary system. we evaluated its osteogenic osteoconductive properties after being...

10.3390/jcm8101714 article EN Journal of Clinical Medicine 2019-10-17

Nowadays, there exists a huge interest in producing innovative, high-performance, biofunctional, and cost-efficient electrospun biomaterials based on the association of biocompatible polymers with bioactive molecules. Such materials are well-known to be promising candidates for three-dimensional biomimetic systems wound healing applications because they can mimic native skin microenvironment; however, many open questions such as interaction mechanism between dressing material remain unclear....

10.3390/polym15122705 article EN Polymers 2023-06-16
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