A5004446959- Plant Parasitism and Resistance
- Asthma and respiratory diseases
- Plant and animal studies
- Allergic Rhinitis and Sensitization
- Plant Molecular Biology Research
- Fungal Biology and Applications
- Microbial Natural Products and Biosynthesis
- Mycorrhizal Fungi and Plant Interactions
- Food Allergy and Anaphylaxis Research
- Legume Nitrogen Fixing Symbiosis
- Photochemistry and Electron Transfer Studies
- Phytochemical compounds biological activities
- Contact Dermatitis and Allergies
- Mast cells and histamine
- Allelopathy and phytotoxic interactions
- Pediatric health and respiratory diseases
- Respiratory and Cough-Related Research
- Drug-Induced Adverse Reactions
- Urticaria and Related Conditions
- Insect Pest Control Strategies
- Studies on Chitinases and Chitosanases
- Radical Photochemical Reactions
- Eosinophilic Disorders and Syndromes
- Nematode management and characterization studies
- Plant-Microbe Interactions and Immunity
Osaka Metropolitan University
2024
Osaka Prefecture University
2013-2022
Japan Science and Technology Agency
2018-2019
National Sagamihara Hospital
2002-2014
Hyogo Prefectural Nishinomiya Hospital
2012
Tokyo Institute of Technology
2012
The University of Tokyo
1977-2007
Tohoku University
1990-2006
Chiba University
2003-2005
Tokyo Denki University
2003-2004
Strigolactones (SLs) stimulate seed germination of root parasitic plants and induce hyphal branching arbuscular mycorrhizal fungi in the rhizosphere. In addition, they have been classified as a new group plant hormones essential for shoot inhibition. It has demonstrated thus far that SLs are derived from carotenoid via biosynthetic precursor carlactone (CL), which is produced by sequential reactions DWARF27 (D27) enzyme two cleavage dioxygenases CCD7 CCD8. We previously found an extreme...
Strigolactones are a group of terpenoid lactones that act as host-derived signal in the rhizosphere communication plants with arbuscular mycorrhizal (AM) fungi and root parasitic weeds well an endogenous plant hormone regulating shoot branching plants. induce hyphal AM at very low concentrations, suggesting highly sensitive perception system for strigolactones present fungi. However, little is known about structural requirements Here, we tested series natural synthetically modified...
Strigolactones (SLs) are a class of terpenoid plant hormones that regulate shoot branching as well being known root-derived signals for symbiosis and parasitism. SL has tricyclic-lactone (ABC-ring) methyl butenolide (D-ring), they connected through an enol ether bridge. Recently, putative biosynthetic intermediate called carlactone (CL), which carbon skeleton is in part similar to those SLs, was identified by biochemical analysis three enzymes, DWARF27, CAROTENOID CLEAVAGE DIOXYGENASE 7...
Both root parasitic plants and arbuscular mycorrhizal (AM) fungi take advantage of strigolactones, released from plant roots as signal molecules in the initial communication with host plants, order to commence parasitism mutualism, respectively. In this study, strigolactones exudates 12 Fabaceae including hydroponically grown white lupin (Lupinus albus), a nonhost AM fungi, were characterized by comparing retention times germination stimulants on reverse-phase high-performance liquid...
Plants are constantly exposed to threats from pathogenic microbes and thus developed an innate immune system protect themselves. On the other hand, many plants also have ability establish endosymbiosis with beneficial such as arbuscular mycorrhizal (AM) fungi or rhizobial bacteria, which improves growth of host plants. How evolved these systems managing opposite plant–microbe interactions is unclear. We show here that knockout (KO) mutants OsCERK1, a rice receptor kinase essential for chitin...
The perception mechanism for the strigolactone (SL) class of plant hormones has been a subject debate because their receptor, DWARF14 (D14), is an α/β-hydrolase that can cleave SLs. Here we show via time-course analyses SL binding and hydrolysis by Arabidopsis thaliana D14, level uncleaved strongly correlates with induction active signaling state. In addition, AtD14
Significance Strigolactone hormones regulate many plant growth and developmental processes are particularly important in regulating response to nonoptimal conditions. Plants produce a range of bioactive strigolactone-like compounds, suggesting that the biosynthesis pathway is complex. Despite this complexity, only one type enzyme, MORE AXILLARY GROWTH1 (MAX1) cytochrome P450, has been attributed diversity strigolactones. Using transcriptomics reverse genetics, we discovered previously...
Abstract In flowering plants, strigolactones (SLs) have dual functions as hormones that regulate growth and development, rhizosphere signaling molecules induce symbiosis with arbuscular mycorrhizal (AM) fungi. Here, we report the identification of bryosymbiol (BSB), an SL from bryophyte Marchantia paleacea . BSB is also found in vascular indicating its origin common ancestor land plants. synthesis enhanced at AM permissive conditions deficient mutants are impaired symbiosis. contrast,...
Major strigolactones (SLs) produced by rice (Oryza sativa L. cv. Nipponbare) and tobacco (Nicotiana tabacum Michinoku No. 1) were purified their stereochemical structures determined comparing with optically pure synthetic standards for NMR CD data retention times mass fragmentations in ESI-LC/MS GC-MS. SLs from root exudates of plants orobanchol, orobanchyl acetate, ent-2'-epi-5-deoxystrigol. In addition to these SLs, 7-oxoorobanchyl acetate the putative three methoxy-5-deoxystrigol isomers...
Strigolactones (SLs) are a class of plant hormones which regulate shoot branching and function as host recognition signals for symbionts parasites in the rhizosphere. However, steps SL biosynthesis after carlactone (CL) formation remain elusive. This study elucidated common diverse functions MAX1 homologs catalyze CL oxidation. We have reported previously that ArabidopsisMAX1 converts to carlactonoic acid (CLA), whereas rice homolog has been shown conversion 4-deoxyorobanchol (4DO). To...
Summary Arbuscular mycorrhiza ( AM ) represents an ancient endosymbiosis between plant roots and G lomeromycota fungi. S trigolactones (SLs), plant‐derived terpenoid lactones, activate hyphal branching of fungi before physical contact. Lack SL biosynthesis results in lower colonization The F ‐box protein, DWARF 3 D3 ), the hydrolase family protein 14 D14 are crucial for responses rice. Here we conducted fungal assays with SL‐insensitive d3 d14 mutants. mutant exhibited strong defects...
The parasitic plant Striga hermonthica has been causing devastating damage to the crop production in Africa. Because requires host-generated strigolactones germinate, identification of selective and potent strigolactone agonists could help control these noxious weeds. We developed a agonist, sphynolactone-7, hybrid molecule originated from chemical screening, that contains two functional modules derived synthetic scaffold core component strigolactones. Cooperative action activation...
To cite this article: Ohta K, Bousquet P-J, Aizawa H, Akiyama Adachi M, Ichinose Ebisawa Tamura G, Nagai A, Nishima S, Fukuda T, Morikawa Okamoto Y, Kohno Saito Takenaka Grouse L, J. Prevalence and impact of rhinitis in asthma: SACRA, a cross-sectional nation-wide study Japan. Allergy 2011; 66: 1287–1295. Background: Asthma are common co-morbidities everywhere the world but studies assessing asthmatics using questionnaires based on guidelines not available. Objective: assess prevalence,...
The structural requirements of strigolactones (SLs) involved in germination induction root parasitic plants and hyphal branching arbuscular mycorrhizal (AM) fungi have been extensively studied. However, our knowledge the SLs shoot inhibition is still limited. To address this question, we investigated structure–activity relationships rice Arabidopsis. possess a four-ring structure, with tricyclic lactone (ABC-rings) connected to methylbutenolide part (D-ring) via an enol ether bridge. Here,...
Significance The origins of arbuscular mycorrhizal (AM) fungi, which form symbiotic associations with land plants, date back >460 Mya. During evolution, these fungi acquired an obligate lifestyle, and thus depend on their host for essential nutrients. In particular, fatty acids are regarded as crucial nutrients the survival AM owing to absence genes involved in de novo acid biosynthesis fungal genomes that have been sequenced so far. Here we show myristate initiates growth under...
Strigolactones (SLs) are a plant hormone inhibiting shoot branching/tillering and rhizospheric, chemical signal that triggers seed germination of the noxious root parasitic Striga mediates symbiosis with beneficial arbuscular mycorrhizal fungi. Identifying specific roles canonical noncanonical SLs, two SL subfamilies, is important for developing Striga-resistant cereals engineering architecture. Here, we report rice mutants lacking SLs do not show phenotypes known SL-deficient plants,...
Significance Strigolactones (SLs) are a group of apocarotenoid hormones, which regulates shoot branching and other diverse developmental processes in plants. The major bioactive form(s) SLs as endogenous hormones has not yet been clarified. Here, we identify an Arabidopsis methyltransferase, CLAMT, responsible for the conversion inactive precursor to biologically active SL that can interact with receptor vitro. Reverse genetic analysis showed this enzyme plays essential role inhibiting...
Abstract Arbuscular mycorrhizal (AM) symbiosis is a mutually beneficial interaction between fungi and land plants promotes global phosphate cycling in terrestrial ecosystems. AM are recognised as obligate symbionts that require root colonisation to complete life cycle involving the production of propagules, asexual spores. Recently, it has been shown Rhizophagus irregularis can produce infection-competent secondary spores asymbiotically by adding fatty acid, palmitoleic acid. Furthermore,...
Melon (Cucumis melo) roots were inoculated with or without the arbuscular mycorrhizal (AM) fungus Glomus caledonium under low phosphate conditions. High-performance liquid chromatography analysis of secondary metabolites in butanol extracts from revealed that level one compound noninoculated showed a significant increase 30 days postinoculation. No accumulation was observed and high-phosphate-supplemented roots, indicating caused by deficiency. The isolated column identified spectroscopic...
Abstract Background Anaphylaxis is a life‐threatening syndrome resulting from the sudden release of mast cell‐ and basophil‐derived mediators into circulation. However, pathological evidence association between inflammatory human anaphylaxis insufficient. Objective The aim this study was to better understand relationship in vivo production pathogenesis anaphylaxis. We also sought evaluate cell activation Methods measured concentrations various urine samples, which were collected 32...