A5050564824- Flowering Plant Growth and Cultivation
- Plant tissue culture and regeneration
- Plant Reproductive Biology
- Renal and related cancers
- Pluripotent Stem Cells Research
- Cardiovascular Syncope and Autonomic Disorders
- Plant Physiology and Cultivation Studies
- Botanical Research and Applications
- Heart Rate Variability and Autonomic Control
- Sperm and Testicular Function
- Neurogenesis and neuroplasticity mechanisms
- RNA regulation and disease
- RNA modifications and cancer
- Plant and animal studies
- Infrared Thermography in Medicine
- Plant Genetic and Mutation Studies
- Neurological Disease Mechanisms and Treatments
- RNA and protein synthesis mechanisms
- Crop Yield and Soil Fertility
- Hereditary Neurological Disorders
- Testicular diseases and treatments
- Agricultural Systems and Practices
- Plant Growth and Agriculture Techniques
- Cardiovascular and exercise physiology
- Microtubule and mitosis dynamics
Yokohama National University
2014-2023
Suzuki (Japan)
2023
Nagoya University
1996-2017
Koshigaya Municipal Hospital
2013
Japanese Red Cross Nagoya Daiichi Hospital
2012
Niigata University
1986-2002
Radboud University Nijmegen
1983
ABSTRACT NANOS2 and NANOS3 belong to the Nanos family of proteins that contain a conserved zinc finger domain, which consists two consecutive CCHC-type motifs, contribute germ cell development in mice. Previous studies indicate there are redundant distinct functions these proteins. rescues maintenance primordial cells, whereas fails replace male pathway. However, lack conditional allele Nanos3 has hampered delineation each contribution In addition, molecular mechanism underlying remains...
Abstract Genetic and phenotypic heterogeneities are considerably high in adult‐onset leukoencephalopathy, which comprehensive mutational analyses of the candidate genes by conventional methods too laborious. We applied exome sequencing to conduct a analysis for autosomal dominant leukoencephalopathies. Genomic DNA samples from four patients three families with dominantly inherited leukodystrophy were subjected sequencing. On basis results, 21 sporadic one patient pathologically proven HDLS...
Polysialic acid (polySia) is mainly found as a modification of neural cell adhesion molecule (NCAM) in whole embryonic brains, well restricted areas adult vertebrate including the hippocampus. PolySia shows not only repulsive effects on NCAM-involved cell-cell interactions due to its bulky and hydrated properties, but also attractive interaction with neurologically active molecules, which exerts reservoir function. Two different polysialyltransferases, ST8SIA2 ST8SIA4, are involved synthesis...
Spontaneous testicular teratomas (STTs) derived from primordial germ cells (PGCs) in the mouse embryonic testes predominantly develop 129 family inbred strain. Ter (spontaneous mutation) is a single nucleotide polymorphism that generates premature stop codon of Dead end1 (Dnd1) and increases incidence STTs genetic background. We previously found DND1 interacts with NANOS2 or NANOS3 these complexes play vital role male adult spermatogonia. However, following are unclear: (a) whether works to...
The present study was performed to test the hypothesis that application of lower body positive pressure (LBPP) during orthostasis would reduce baroreflex-mediated enhancement in sympathetic activity humans. Eight healthy young men were exposed a 70° head-up tilt (HUT) on 30 mmHg LBPP. Muscle nerve (MSNA) microneurographically recorded from tibial nerve, along with hemodynamic variables. We found supine position LBPP, MSNA remained unchanged (13.4 ± 3.3 vs. 11.8 2.3 bursts/min, without LBPP;...
The neural cell adhesion molecule (NCAM) is modified by polysialic acid (polySia or PSA) in embryonic brains. In adult brains, polySia modification of NCAM only observed restricted areas where plasticity, remodeling connections, generation ongoing although the amount remains unchanged. Impairments polySia-expression and several single nucleotide polymorphisms (SNPs) polysialyltransferase (polyST) ST8SIA2 gene are reported to be associated with schizophrenia bipolar disorder. Chlorpromazine...
To test the hypothesis that mist sauna is a safer way of bathing than dry sauna, we compared changes in circulatory and thermoregulatory functions during 10 min at 40℃ with relative humidity 100%, by infrared ray 70℃ 15%. Subjects were seven healthy young men aged 29 ± 6 yrs (mean SD). We measured blood pressure, heart rate, skin temperatures chest, forearm, thigh, leg, tympanic temperature (Tty) thermistors, flow forearm laser Doppler flowmetry, sweat rate ventilated capsule method 1...
Spontaneous testicular teratomas (STTs) are tumours comprising a diverse array of cell and tissue types, which derived from pluripotent stem-like cells called embryonal carcinoma (ECCs). Although mouse ECCs originate primordial germ (PGCs) in embryonic testes, the molecular basis underlying ECC development remains unclear. This study shows that conditional deletion Dead end1 (Dnd1) migrating PGCs leads to STT development. In Dnd1-conditional knockout (Dnd1-cKO) embryos, colonise testes but...
Three 5 mm strips excised from the basal region of young leaves 6 Lilium species were cultured in vitro, and rates regeneration number bulblets per explant investigated. The bulblet productivity depended both on kind origins each explant. Growth regulators also affected productivity; α-naphthaleneacetic acid (NAA) was absolutely required for induction growth whereas addition 6-benzylaminopurine (BA) ineffective.
Factors affecting the initiation and elongation of stems from bulblets developed on scales ‘White Aga’ (Lilium x formolongi) were examined by low-temperature treatment bulbscales cultured in darkness or culturing them a medium with colchicine at 25°C. Scale explants excised vitro-cultured for total 180 days darkness. First, they MS 0.54 µM NAA 4.4 44 BA 25°C 30 days, then further subcultured under following conditions: (1) continuously 150 (control) µ BA; (2) 8°C 60 followed culture 90...
Bulbs of Tulipa gesneriana ‘Queen Night’ at stage G3 were treated with low temperature 4°C or 8°C for 0 to 10 weeks and then grown under forcing conditions in a greenhouse. The developmental process microspores different treatments follows similar pattern, irrespective the duration temperature. Pollen remained uninucleate long time after planting, rapidly developed into binuclear about one week before anthesis mature pollen. Generally, days from planting decreased, while percentage stainable...
Zephyra elegans D. Don is a Chilean endemic geophyte specie from the Tecophilaceae family, described as having high potential an ornamental crop. Flowering capacity has been to be related corm weight. can only seen in corms over 0.3 g. Experiments were performed initiate seeds vitro and obtain enhanced weight gain. Initiation of was MS medium. Eight weeks after seed germination, plantlets transferred different mediums with sucrose concentrations 0, 30, 60, 90 120 g·L -1 . The objective...
<title>Abstract</title> Spontaneous testicular teratomas (STTs) are tumours comprising a diverse array of cell and tissue types, which derived from pluripotent stem-like cells called embryonal carcinoma (ECCs). Although mouse ECCs originate primordial germ (PGCs) in embryonic testes, the molecular basis underlying ECC development remains unclear. This study shows that conditional deletion Dead end1 (<italic>Dnd1</italic>) migrating PGCs leads to STT development....