A5100434748- Anesthesia and Sedative Agents
- Airway Management and Intubation Techniques
- Dental Anxiety and Anesthesia Techniques
- Pain Mechanisms and Treatments
- Anesthesia and Neurotoxicity Research
- Tracheal and airway disorders
- Anesthesia and Pain Management
- Silk-based biomaterials and applications
- Electrospun Nanofibers in Biomedical Applications
- Intensive Care Unit Cognitive Disorders
- Bone Tissue Engineering Materials
- Botulinum Toxin and Related Neurological Disorders
- Obstructive Sleep Apnea Research
- Pharmacological Effects of Natural Compounds
- Foreign Body Medical Cases
- Inflammatory mediators and NSAID effects
- EEG and Brain-Computer Interfaces
- Viral Infections and Immunology Research
- Cardiac, Anesthesia and Surgical Outcomes
- Neuroscience and Neuropharmacology Research
- Parkinson's Disease Mechanisms and Treatments
- Amyotrophic Lateral Sclerosis Research
- Viral gastroenteritis research and epidemiology
- Healthcare Education and Workforce Issues
- Nausea and vomiting management
Seoul National University Dental Hospital
2014-2025
Seoul National University
2015-2024
Kangwon National University
2005-2024
Gyeongsang National University
2024
National Institute of Environmental Research
2014-2024
Ministry of Environment
2023-2024
Yonsei University
2003-2024
Seoul National University Hospital
2005-2023
Korea University of Technology and Education
2023
Korea Disease Control and Prevention Agency
2022
The stereotype content model (SCM) proposes potentially universal principles of societal stereotypes and their relation to social structure. Here, the SCM reveals theoretically grounded, cross‐cultural, cross‐groups similarities one difference across 10 non‐US nations. Seven European (individualist) three East Asian (collectivist) nations ( N =1,028) support hypothesized cross‐cultural similarities: (a) perceived warmth competence reliably differentiate group stereotypes; (b) many out‐groups...
Abstract Reliable electroencephalography (EEG) signatures of transitions between consciousness and unconsciousness under anaesthesia have not yet been identified. Herein we examined network changes using graph theoretical analysis high-density EEG during patient-titrated propofol-induced sedation. Responsiveness was used as a surrogate for consciousness. We divided the data into five states: baseline, transition unresponsiveness, responsiveness, recovery. Power spectral showed that delta...
The authors argue that complementary hostile and benevolent components of sexism exist across cultures.Male dominance creates (HS), but men's dependence on women fosters (BS)--subjectively positive attitudes put a pedestal reinforce their subordination.Research with 15,000 men in 19 nations showed (a) HS BS are coherent constructs correlate positively nations, (b) predicts the ascription negative traits to women, (c) relative men, more likely reject than BS, especially when overall levels...
Curcumin has diverse therapeutic effects, such as anti-inflammatory, anti-oxidant, anti-cancer, and antimicrobial activities. The vanilloid moiety of curcumin is considered important for activation the transient receptor potential 1 (TRPV1), which plays an role in nociception. However, very little known about effects on In present study, we investigated whether anti-nociceptive are mediated via TRPV1 by using nociceptive behavioral studies vitro whole-cell patch-clamp recordings trigeminal...
We developed three-dimensional electrospun silk fibroin (ESF) scaffolds with controllable pore size. The purpose of this study was to evaluate ESF pores (P-ESF) for bone regeneration via in vitro and vivo studies, a comparison commercially available porous polylactic acid (PLA) scaffold. P-ESF supported significantly higher proliferation alkaline phosphatase activity osteoblasts than PLA (p < 0.05). Moreover, expression levels activated adhesion-related proteins, including focal adhesion...
Some plant flavonoids in the form of whole extracts have been used topically for skin inflammatory disorders. Since matrix metalloproteinase-1 (MMP-1, collagenase-1) plays an important role unbalanced turn-over or rapid breakdown collagen molecules human inflamed/UV-irradiated skin, effects natural on MMP-1 activity and expression were studied to establish therapeutic potential. Against recombinant MMP-1, flavonols such as quercetin kaempferol strong inhibitors with IC50 values 39.6 43.7 μM,...
In the search for a new thermogelling biomaterial, we are reporting poly(ethylene glycol)−poly(trimethylene carbonate) (PEG−PTMC) diblock copolymers. The PEG−PTMC (550−2750) copolymer aqueous solutions (>25 wt %) underwent sol-to-gel-to-syneresis (macroscopic phase separation between polymer and water) transition as temperature increased. sol-to-gel could be controlled in range of 20−75 °C by varying concentration water, molecular weight, composition polymer. 13C NMR spectra, transmission...
Recent advances in automated cell counters enable us to count cells more easily with consistency. However, the wide use of traditional vital dye trypan blue (TB) raises environmental and health concerns due its potential teratogenic effects. To avoid this chemical hazard, it is importance introduce an alternative non-hazardous that compatible counters. Erythrosin B (EB) a impermeable biological membranes used as food additive. Similarly TB, EB stains only nonviable disintegrated membranes....
We study the synchronization phenomena in a system of globally coupled oscillators with time delay coupling. The self-consistency equations for order parameter are derived, which depend explicitly on amount delay. Analysis these reveals that general exhibits discontinuous transitions addition to usual continuous transition, between incoherent state and multitude coherent states different frequencies. In particular, phase diagram is obtained plane coupling strength time, ubiquity...
A paucity of reports exist on the use botulinum toxin type injections as an alternative noninvasive treatment for masseteric hypertrophy.To evaluate effects hypertrophy using computed tomography.Percutaneous intramuscular 30 U per side was carried out in 11 subjects with hypertrophy. The changes muscle volume before and 12 weeks after injection were evaluated tomography. lower facial contours photographs excellent, good, fair, no changes.Nine showed a mean reduction approximately 22% volume....
Local anesthetics have been generally accepted as being safe. However, recent clinical trials and basic studies provided strong evidence for the neurotoxicity of local anesthetics, especially through apoptosis. We hypothesized that cause neural complications Schwann cell Among tested on line, RT4-D6P2T, bupivacaine significantly induced death, measured by methyl tetrazolium (MTT) assay, in a dose- (LD 50 = 476 μM) time-dependent manner. The bupivacaine-induced generation reactive oxygen...
Mutations in Cu,Zn superoxide dismutase (SOD1) are associated with familial amyotrophic lateral sclerosis (ALS). Mutant SOD1 causes a complex array of pathological events, through toxic gain function mechanisms, leading to selective motor neuron degeneration. Mitochondrial dysfunction is among the well established effects mutant SOD1, but its mechanisms just starting be elucidated. A portion localized mitochondria, where it accumulates mostly on outer membrane and inside intermembrane space...
Amyotrophic lateral sclerosis is a devastating neurodegenerative disorder that more prevalent in males than females. A similar gender difference has been reported some strains of transgenic mouse models familial amyotrophic harbouring the G93A mutation CuZn superoxide dismutase. Mitochondrial damage caused by pathological alterations Ca(2+) accumulation frequently involved diseases, including dismutase-related sclerosis, but its association with not firmly established. In this study, we...
The aim of this study was to evaluate the regenerative capacity a newly developed nerve guidance conduit using electrospun silk fibroin (SFNC) implanted in 10-mm defect sciatic rats. After evaluating physical properties and cytocompatibility SFNC vitro, rats were randomly allocated into three groups: only, autograft SFNC. To compare motor function abnormal sensation among groups, ankle stance angle (ASA) severity autotomy observed for 10 weeks after injury. Immunostaining with axonal...
A fused-deposition modeling (FDM) 3D-printed polyethylene terephthalate glycol (PETG)–sepiolite composite showed effective synergetic mechanical reinforcement in tensile testing compared to an injection-molded composite. The results that the addition of 3 phr sepiolite improved strength PETG samples by 35.4%, while was 7.2%. To confirm these phenomena, FDM PETG–sepiolite composites were investigated small-angle X-ray scattering correlate nanostructures with their strengths. data and...
People with special needs tend to require diverse behavioral management in dentistry. They may feel anxious or uncomfortable not respond any communication the dentists. Patients medical, physical, psychological disorders cooperate and therefore sedation (SED) general anesthesia (GA) receive dental treatment. Using healthcare big data Korea, this study aimed analyze trends of SED GA patients undergoing It is believed that these can be used as reference material for hospitals preparation...
Postoperative pain management is challenging in patients with oral cancer, especially those undergoing reconstructive surgery. Patient-controlled analgesia (PCA) widely used, and fentanyl (FTN) concentration adjustments may improve control. This study aimed to evaluate the effects of FTN PCA surgery on postoperative cancer. retrospective observational analyzed 140 cancer who underwent under general anesthesia. Patients were categorized based dosage (FTN 700 mcg ketorolac 150 mg vs. 1400 mg)....
The protective effects of red ginseng saponins against carbon tetrachloride-induced hepatotoxicity were investigated in male Sprague Dawley rats. total standardized on ginsenosides-Rb1, -Rb2, -Re, -Rd, -Rc, and -Rg1 used the present study. rats administered orally at 50, 100, 200 mg/kg for 7 consecutive days, followed by an administration tetrachloride 0.4 ml/kg corn oil intraperitoneally 24 h. saponin changed neither body organ weights nor hematological serum clinical parameters. elevation...
A possible role of cytochrome P450 (P450) inhibition by red ginseng saponins in carbon tetrachloride (CCl4)-induced lipid peroxidation was investigated liver microsomes prepared from male Sprague Dawley rats. The total saponin standardized on ginsenosides-Rb1, -Rb2, -Rc, -Rd, -Re, and -Rg1 whose composition studied our previous report used the present study. showed inhibitory effects P450-associated monooxygenase activities a dose-dependent manner, particularly p-nitrophenol hydroxylase...