A5100673346- Muscle Physiology and Disorders
- Heat shock proteins research
- Diverse Approaches in Healthcare and Education Studies
- Neurobiology and Insect Physiology Research
- PARP inhibition in cancer therapy
- Insect Utilization and Effects
- Meat and Animal Product Quality
- Renal cell carcinoma treatment
- Muscle metabolism and nutrition
- Lung Cancer Treatments and Mutations
- Renal and related cancers
- Adipose Tissue and Metabolism
- Animal Genetics and Reproduction
- Viral Infectious Diseases and Gene Expression in Insects
- Stroke Rehabilitation and Recovery
- Photosynthetic Processes and Mechanisms
- Plant Reproductive Biology
- Brain Metastases and Treatment
- Plant Molecular Biology Research
- Transcranial Magnetic Stimulation Studies
- Exercise and Physiological Responses
- Health and Wellbeing Research
- Foot and Ankle Surgery
- Molecular Biology Techniques and Applications
- Microbial Metabolism and Applications
Jeonbuk National University
2021-2024
Hallym University Sacred Heart Hospital
2023
Chonbuk National University Hospital
2020
University of Tsukuba
2019
Soonchunhyang University Hospital
2016
New York Institute of Technology
2014
Massachusetts General Hospital
2014
Center for Cancer Research
2014
Hanyang University
2010
Texas A&M University
2007
There is an unmet clinical need for biomarkers to identify breast cancer patients at increased risk of developing brain metastases. The objective gene signatures and biological pathways associated with human epidermal growth factor receptor 2-positive (HER2+) metastasis.We combined laser capture microdissection expression microarrays analyze malignant epithelium from HER2+ metastases that nonmetastatic primary tumors. Differential was performed including set enrichment analysis (GSEA) using...
Acute kidney injury (AKI) is a common and significant medical problem. Despite the kidney's remarkable regenerative capacity, mortality rate for AKI patients high. Thus, there remains need to better understand cellular mechanisms of nephron repair in order develop new strategies that would enhance intrinsic ability tissue regenerate. Here, using novel, laser ablation-based, zebrafish model AKI, we show collective migration epithelial cells primary early response acute injury. We also cell...
Objective: The growth rate of pigs is related to differentiation and proliferation muscle cells, which are regulated by factors expression growth-related genes. Thus, the objective this study was establish optimal culture conditions for Jeju black pig (JBP) cells determine relationship various involved in with JBP cells. Methods: Muscles were taken from femur skeletal embryos. After isolation cultured a 6-well plate under four different optimize To analyze these seeded into plates at density...
Heat stress inhibits cellular proliferation and differentiation through the production of reactive oxygen species. Under conditions, antioxidant drugs promote stable function by reducing level. We sought to demonstrate 9-mer disulfide dimer peptide (COPA3) supplementation stabilizes fibroblast even under heat conditions. In our study, fibroblasts were assigned two different groups based on temperature, like 38°C group presented as Control - 43°C Stress-. Each was subdivided into depending...
Heat stress (HS) affects cell culture as well animal production. Although there have been many reports on the disparate effects of heat stress, its mammalian muscle stem cells are still unclear. In this study, we isolated porcine satellite (PMSCs) from femurs 1-day-old piglets, and cultured them under three temperature conditions: 37 °C, 39 41 °C. Exposure to HS not only decreased viability proliferation rates PMSCs, but also regulated cycle induced apoptosis. High-temperature conditions...
Background:The coronavirus disease 2019 pandemic has expanded noncontact health care systems worldwide. Transcranial direct current stimulation (tDCS) is a noninvasive brain technology that enables treatment monitoring under remote supervision. We investigated the factors affecting patients' decision to participate in telerehabilitation (TR) using tDCS for motor function recovery after suffering stroke.Materials and Methods:Four medical institutions surveyed 156 patients with poststroke...
Mesenchymal stem cells (MSCs) are promising candidates for tissue regeneration, cell therapy, and cultured meat research owing to their ability differentiate into various lineages including adipocytes, chondrocytes, osteocytes. As MSCs display different characteristics depending on the of origin, appropriate need be selected according purpose research. However, little is known unique properties in pigs. In this study, we compared two types porcine mesenchymal isolated from dorsal...
We aimed to determine the effects of oleic acid (OA) and palmitic (PA), alone or in combination, on proliferation, differentiation, triacylglycerol (TAG) content, gene expression porcine muscle satellite cells (PMSCs). Results revealed that OA-alone- PA + OA-treated PMSCs showed significantly increased viability than those control PA-alone-treated groups. No significant apoptosis were observed all three treatments, whereas necrosis was lower groups Myotube formation OA-alone PMSCs. mRNA...
Abstract Parthenocarpy is the development of an ovary into a seedless fruit without pollination. The ubiquitous downregulation SlIAA9 induces not only parthenocarpic formation but also abnormal vegetative phenotype. To make transgenic tomato plants unwanted phenotypes, we found two genes, namely, Solyc03g007780 and Solyc02g067760 , expressed in tissue tissues. was developing ovaries anthers. mRNA detected whole-flower promoters (Psol80) (Psol60) predominantly induced expression genes ovule,...
Insects are a valuable natural source that can produce variety of bioactive compounds due to their increasing species diversity. CopA3 is an antimicrobial peptide derived from <italic>Copris tripartitus</italic> (i.e., the dung beetle). It known increase proliferation colonic epithelial and neuronal stem cells by regulating cell cycle. This research hypothesized promote porcine muscle satellite (MSCs). The effects on MSCs, which important for growth regeneration, remain unclear. Here, we...
X-linked agammaglobulinemia (XLA) is a hereditary humoral immunodeficiency that results from Bruton's tyrosine kinase (BTK) gene mutations. These mutations cause defects in B-cell development, resulting the virtual absence of these lymphocytes peripheral circulation. Consequently, this leads to profound deficiency lg all isotypes, and an increased susceptibility encapsulated bacterial infections. A 15-month-old Korean boy presented with recurrent sinusitis otitis media after 6 months age,...
The purpose of this study was to explore the effects treadmill training using progressive dual-task on balance and gait function subacute stroke patients. A randomized assigned 25 participants an experimental group (n=13) a control (n=12). All performed 30 min daily, three days week for 4 weeks. completed by gradually applying each while running treadmill. Due discharge refusal, 5 people from dropped out, leaving total 16 complete study. Walking ability measured 10-m walk test (10MWT) 6-min...
Abstract Background Jeju black pig (JBP), one of Korean native breeds, has excellent meat quality but grow slowly. The growth rate pigs is related to differentiation and proliferation muscle cells regulated by factors expression growth-related genes. However, few studies have determined the effect on porcine cells. Thus, objective this study was establish optimal culture conditions JBP determine relationship various involved in with Results We established a cell line from embryos optimized...
중증 장애를 가진 아동은 신체의 기능유지와 생존을 위해 지속적인 재활치료가 필요하다. 그러나 소아재활치료의 과소 공급과 수도권 편중으로 인해 수많은 장애아동 가족은 일명 “재활 난민”으로 살아왔다. 이러한 문제인식을 공유하며 2014년 결성된 대전지역 가족모임 (사)토닥토닥은 초기에 타 시민사회운동 단체를 통해 문제를 해결하려고 하였으나 충분히 받아들여지지 않자, 직접 공공어린이재활병원 설립의 목소리를 내며 운동을 확장하였다. 그 결과 국내 첫 공공어린이재활병원이 2022년 10월 대전에 설립될 예정이다. 본 연구는 장애아동의 치료문제가 어떻게 사회적 소구력을 갖고 정치적 쟁점으로 부상할 수 있었는지 과정과 의미를 탐색하는 것을 목적으로 한다. 과정에서 및 가족의 풀뿌리 옹호활동이 촛불혁명으로 상징되는 기회구조 확대라는 외부적 조건 변화 속에서 당사자-이해관계자 간 유연한 연대를 운동의 성과를 만들어냈는지 살펴보았다.
Heat stress inhibits cell proliferation as well animal production. Here, we aimed to demonstrate that 9-mer disulfide dimer peptide (CopA3) supplementation stabilizes porcine muscle satellite (PMSC) and heat shock protein (HSP) expression at different temperatures. Therefore, investigated the beneficial effects of CopA3 on PMSCs three temperatures (37, 39, 41 °C). Based temperature treatment, were divided into six groups including treatment control for each temperature. Cell viability was...
Abstract Background Pre-slaughter process during transportation, handling, and lairage causes stress in pigs, affecting animal welfare meat quality. Therefore, factors are important for relieving stress. A total of 24 LYD (Landrace × Yorkshire Duroc) barrows were used to investigate the effect 6 20 h time (LT) on cortisol, serotonin, catecholamine blood physiological muscle, verify causal relationship between these factors. Results The results revealed that cortisol was increased (0.064 ±...