A5023369947- Heavy Metal Exposure and Toxicity
- Air Quality and Health Impacts
- Toxic Organic Pollutants Impact
- Radioactivity and Radon Measurements
- Carcinogens and Genotoxicity Assessment
- Mercury impact and mitigation studies
- Effects and risks of endocrine disrupting chemicals
- Heavy metals in environment
- Effects of Radiation Exposure
- Radioactive contamination and transfer
- Aluminum toxicity and tolerance in plants and animals
- Anesthesia and Neurotoxicity Research
- Radiation Therapy and Dosimetry
- Pesticide Exposure and Toxicity
- Neurogenesis and neuroplasticity mechanisms
- Trace Elements in Health
- Radiation Dose and Imaging
- Glioma Diagnosis and Treatment
- Sulfur Compounds in Biology
- Drug-Induced Hepatotoxicity and Protection
- Hedgehog Signaling Pathway Studies
- Prenatal Substance Exposure Effects
- Biomarkers in Disease Mechanisms
- Sperm and Testicular Function
- Ocular Oncology and Treatments
Institut d'Investigació Sanitària Pere Virgili
2010-2024
Universitat Rovira i Virgili
2008-2022
Technological Center of Nutrition and Health
2009-2015
Brain Physiology Lab
2007
Society of Environmental Toxicology and Chemistry
2007
Environmental Health
2007
Therapeutic irradiation of pediatric and adult patients can profoundly affect neurogenesis, cognitive impairment manifests as a deficit in hippocampal-dependent functions. Age plays major role susceptibility to radiation, younger children are at higher risk decay when compared adults. Cranial affects hippocampal neurogenesis by induction DNA damage neural progenitors, through the disruption neurogenic microenvironment, defective integration newborn neurons into neuronal network. Our goal...
The protective role of exogenous melatonin on U-induced nephrotoxicity was investigated in rats. Animals were given single doses uranyl acetate dihydrate (UAD) at 5 mg/kg (subcutaneous), 10 or 20 (intraperitoneal), and UAD (5 mg/kg) plus (10 mg/kg), vehicle (control group). In comparison with the UAD-treated group only, significant beneficial changes noted some urinary serum parameters rats concurrently exposed to melatonin. increase U excretion after administration accompanied by a...
Many genes controlling neuronal development also regulate adult neurogenesis. We investigated in vivo the effect of Shh signaling activation on patterning and neurogenesis hippocampus behavior Patched1 heterozygous mice (Ptch1+/-). demonstrated for first time, that Ptch1+/- exhibit morphological, cellular molecular alterations dentate gyrus (DG), including elongation reduced width DG as well deregulations at multiple steps during lineage progression from neural stem cells to neurons. By...
Breast cancer (BC) is one of the most important neoplasias among women. Many patients receive radiotherapy (RT), which involves radiation exposure thoracic zone, including heart and blood vessels, leading to development cardiovascular disease (CVD) as a long-term side effect. The severity CVD-related pathologies leads research on assessing novel CVD biomarkers diagnostic, prognostic or therapeutic agents. Currently, possible candidates include microRNAs (miRNAs). Previous studies have...
The aim was to determine the levels and activities of oxidative stress markers in erythrocytes, plasma, urine after a flat cyclist stage. Eight voluntary male professional trained-cyclists participated study. Exercise significantly increased erythrocyte, leukocyte, platelet, reticulocyte counts. exercise induced significant increases erythrocyte catalase (19.8%) glutathione reductase (19.2%), while peroxidase activity decreased (29.3%). Erythrocyte GSSG concentration (21.4%), whereas GSH...