A5088818307- Renal Transplantation Outcomes and Treatments
- Renal Diseases and Glomerulopathies
- Chronic Kidney Disease and Diabetes
- Pharmacological Effects and Toxicity Studies
- Hepatitis B Virus Studies
- Nutrition and Health in Aging
- Tumors and Oncological Cases
- Cytomegalovirus and herpesvirus research
- Parvovirus B19 Infection Studies
- Dialysis and Renal Disease Management
- Renal function and acid-base balance
- Neurological Complications and Syndromes
- Vaccine Coverage and Hesitancy
- Organ Transplantation Techniques and Outcomes
- Infectious Diseases and Tuberculosis
- Parathyroid Disorders and Treatments
- Clinical Reasoning and Diagnostic Skills
- Diet and metabolism studies
- Liver Disease and Transplantation
- HIV-related health complications and treatments
- Metabolism and Genetic Disorders
- Hepatitis Viruses Studies and Epidemiology
- Higher Education Learning Practices
- Pediatric Urology and Nephrology Studies
- Ion Transport and Channel Regulation
Universidade de São Paulo
2014-2024
Fundação Faculdade de Medicina
2023
Weatherford College
2023
Universidade de Ribeirão Preto
2012-2021
Clinics Hospital of Ribeirão Preto
2011-2021
Acute kidney injury (AKI) has increasingly been recognized as an important public health issue due to its rising frequency, associations with early and late adverse outcomes economic burden. Given the importance of determining available resources address this serious issue, AKI Committee SLANH conducted a survey obtain information about infrastructure, human equipment devoted treatment in Latin America A total 246 units from 14 countries participated survey, majority them pertaining...
Tacrolimus (TAC) is one of the most successful immunosuppressive drugs in transplantation. Its pharmacokinetics (PK) and pharmacogenetics (PG) have been extensively studied, with many studies showing influence CYP3A5 on TAC metabolism bioavailability. However, data concerning functional significance ABCB1 polymorphisms are uncertain due to inconsistent results. We evaluated association between diplotypes, disposition a cohort Brazilian transplant recipients.Individuals were genotyped for...
This analysis, using data from the Brazilian kidney transplant (KT) COVID-19 study, seeks to develop a prediction score assist in risk stratification KT recipients. In this 1379 patients (35 sites) were enrolled, and machine learning approach was used fit models derivation cohort. A reduced Elastic Net model selected, accuracy predict 28-day fatality after diagnosis, assessed by area under ROC curve (AUC-ROC), confirmed validation The better calibration values build applicable ImAgeS score....
The objective of the present study was to determine frequency most common clinical features in patients with autosomal dominant polycystic kidney disease a sample Brazilian population. medical records 92 attended during period from 1985 2003 were reviewed. following data recorded: age at diagnosis, gender, associated manifestations, occurrence stroke, loss renal function (beginning dialysis), and presence family history. involvement abdominal viscera investigated by ultrasonography....
The objectives of our study were as follows: 1) to analyze the prognostic value macrophage infiltration in primary IgA nephropathy (IgAN) and 2) relationship between macrophages other factors associated with development renal fibrosis, including mast cells, TGF-β1, α-SMA NF-kB.We analyzed 62 patients who had been diagnosed IgAN 1987 2003. Immunohistochemical staining was performed monoclonal antibodies against CD68 cell tryptase polyclonal NF-kB p65. We also used Southwestern histochemistry...
Abstract: Introduction: The Progress Test (PT) is a well-established and mostly successful modality of student knowledge assessment in the health professions, mainly those medical area, with potential to contribute substantially formative informative purposes (quality control indication improvement teaching-learning processes). Additionally, PT has characteristics that are adequate for its inclusion institutional evaluation systems facilitate purpose, such as programmatic (PA), but also meet...
Bloodstream infections are the second most common cause of death among patients on hemodialysis. This study aimed to evaluate incidence and risk factors associated with central venous catheter-related in undergoing hemodialysis, identify characterize type antimicrobial susceptibility profiles primary microorganisms isolated during one year follow-up.A prospective cohort was conducted 2014 a hemodialysis referral center. We included 200 outpatients acute kidney injury who had no permanent...
There are many infectious complications related to vascular access in patients undergoing maintenance hemodialysis. We report two cases of endophthalmitis as a metastatic infection associated with tunneled catheter and temporary dual lumen catheter. Both were diabetic. A 61-year-old female on hemodialysis by jugular tunnelized during the past year was receiving parenteral antibiotics for salvage due fever episodes last 3 months. She admitted hospital presenting pain, proptosis, conjunctival...
Urinary tract infections (UTI) among transplant recipients are usually caused by gram-negative microorganisms and can provoke a high incidence of morbidity mortality. The aim this study was to evaluate the risk factors associated with acquisition UTIs during first year after renal transplantation.Here, we report single-center retrospective cohort 99 patients followed for surgery. definition UTI episode urine culture showing bacterial growth leucocyturia when presented urinary symptoms....
Overweight, obese and chronic kidney disease patients have an altered negative body composition being its assessment important. Bioelectrical impedance analysis is easy-to-operate low-cost method for this purpose. This study aimed to compare correlate data from single- multi-frequency bioelectrical spectroscopy applied in subjects with different sizes, adiposity, hydration status. It was a cross-sectional 386 non-chronic volunteers (body mass index 17 40 kg/m2), 30 peritoneal dialysis, 95...
<i>Background/Aims:</i> The urinary concentration of the monocyte chemoattractant protein-1 (uMCP-1) chemokine is increased in several proteinuric and/or inflammatory renal diseases. In present study, we evaluated association between uMCP-1 and function, proteinuria, glomerular interstitial macrophage infiltration, fibrosis patients with primary secondary glomerulopathies diagnosed by biopsy. <i>Methods:</i> Thirty-seven aged 32.6 ± 7.7 years were studied. was...
To evaluate the association between nutritional status, resting energy expenditure (REE), and protein oxidative stress in patients after kidney transplantation (KT).The study evaluated 35 transplanted at time of hospital discharge 3 months regarding: body composition, REE (by indirect calorimetry), injury factor (IF); serum urea, creatinine, glucose, albumin, total protein, advanced oxidation products (AOPP), vitamin C.Three discharge, there was an improvement renal function, stress, with a...
We present a case of ocular syphilis after renal transplantation involving progressive vision loss without clinically identifiable disease. Electroretinography showed signs ischemia, especially in the internal retina. A serological test was positive for syphilis. Lumbar puncture revealed lymphocytic meningitis and serologic cerebrospinal fluid. The patient treated with penicillin, had quick improvement. In transplant recipients, clinicians should always consider diagnosis cases unexplained...
To investigate primary care physicians' knowledge of and attitudes toward for chronic kidney disease patients.In Brazil, disease, a global public health problem, is provided by the Brazilian National Health System, which organized around care. The study aimed to physicians about management disease.This research based on quantitative qualitative data. participants were 92 from 81 units located in eight cities São Paulo/Brazil region, who answered self-administered questionnaire.Only 59% 58%...
Previous studies have shown that education level is associated with the prognosis of cadaveric kidney transplant recipients. However, it unclear whether affects living (LDKT) In addition, remains to be determined uneven distribution educational levels consistently LDKT recipients across ethnic groups (White, Black, Hispanic and Asian).After establishing inclusion exclusion criteria, we conducted a retrospective study who received their first single between 2005 2020. The were divided into...
Inflammatory cell infiltration and residual areas of fibrosis in kidneys after renal transplantation can lead to functional abnormalities with long-term implications.The aim this study was determine urinary monocyte chemoattractant protein-1 (uMCP-1) levels, relative cortical interstitial area (RCIA), tubulointerstitial macrophage transplant patients delayed graft function (DGF) their possible correlation outcome.Patients were followed biopsies for one year, structure evaluated, as well...
Hypercalcemia is common in patients after kidney transplantation (KTx) and associated with persistent hyperparathyroidism the majority of cases. This retrospective, single-center study evaluated prevalence hypercalcemia KTx. KTx recipients were for 7 years receiving kidneys from living or deceased donors. A total 301 evaluated; 67 had at some point during follow-up period. The median time all was 62 months (44; 80). Overall, 45 cases classified as related to post-transplant (group A), 16...
Objective: to identify the prevalence of latent tuberculosis in patients with chronic kidney disease on hemodialysis and associated factors. Method: a cross-sectional study conducted 176 hemodialysis. The tuberculin test was performed standardized antigen, distributed by Brazilian Ministry Health, reading occurred after 72 96 hours application. An association (Chi-square, Fisher’s exact), ratio, multivariate regression tests were performed. Results: diagnosed through Tuberculosis Skin Test...
The elderly population is growing and aging in better clinical conditions than the past. However, distribution course of kidney diseases patients are not well known partially due to reluctance indicate renal biopsies those patients.To evaluate distribution, features, outcomes nephropathies diagnosed by biopsy elderly.Seventy-one (47 males, 24 females) aged 60 years or older (67.3 ± 6.5 years), undergoing from January 1990 December 2006, were evaluated. They grouped according their...
Glomerulonephritis may complicate the course of a wide variety malignant diseases. However, there are relatively few reports membranous glomerulonephritis (MGN) in patients with non-Hodgkin lymphoma (NHL). We describe for first time case MGN associated splenic marginal zone extreme plasmacytic differentiation and bone marrow infiltration mimicking multiple myeloma. also reviewed literature summarize clinical-pathological findings mechanisms involved NHL-induced MGN. Our current highlights...
Fabry disease is an X-linked inborn error of metabolism, which caused by the deficiency α-galactosidase A, leading to progressive accumulation neutral glycosphingolipids and a-galactosyl breakdown products in most body fluids several tissues, resulting clinical manifestations. The onset symptoms females not observed as early males. We report a novel presentation female patient with medical history relapsing strokes brain magnetic resonance angiography showing signs microangiopathy...
Abstract Nucleoside/nucleotide analogs such as tenofovir, have been used long-term therapy for the treatment of hepatitis B and side effects reduction in bone mineral density associated with their use. To determine relationships between bone, hormonal, biochemical, parameters patients treated nucleoside/nucleotide antiviral. A cross-sectional study was conducted 81 adult chronic infection. Dual-energy X-ray absorptiometry (DXA) performed to assess density. Biochemical analyses were...