- Retinal Diseases and Treatments
- Retinal Imaging and Analysis
- Digital Radiography and Breast Imaging
- Vascular Procedures and Complications
- Peripheral Artery Disease Management
- Glaucoma and retinal disorders
- Cardiac Imaging and Diagnostics
- Retinal and Optic Conditions
- Radiology practices and education
- Cardiac, Anesthesia and Surgical Outcomes
- Radiation Dose and Imaging
- Lung Cancer Diagnosis and Treatment
- Cardiovascular Effects of Exercise
- Venous Thromboembolism Diagnosis and Management
- Cardiac electrophysiology and arrhythmias
- Coronary Interventions and Diagnostics
- Ophthalmology and Visual Impairment Studies
- Advanced Radiotherapy Techniques
- COVID-19 diagnosis using AI
- Cardiac Valve Diseases and Treatments
- Central Venous Catheters and Hemodialysis
- Advanced X-ray and CT Imaging
- Diabetes Treatment and Management
- Sports injuries and prevention
- Ultrasound in Clinical Applications
Joslin Diabetes Center
1999-2021
Cleveland Clinic Lerner College of Medicine
2018
Harvard University
2007-2017
University of Toronto
2017
Lunenfeld-Tanenbaum Research Institute
2017
Mount Sinai Hospital
2017
Harvard University Press
2012-2015
American University of Beirut
2014
Sahlgrenska University Hospital
1978-1991
Durham Technical Community College
1991
OBJECTIVE: To determine the effectiveness of vitamin E treatment in normalizing retinal blood flow and renal function patients with <10 years type 1 diabetes. RESEARCH DESIGN AND METHODS: An 8-month randomized double-masked placebo-controlled crossover trial evaluated 36 diabetic 9 nondiabetic subjects. Subjects were randomly assigned to either 1,800 IU E/day or placebo for 4 months followed, after crossover, a further months. Retinal was measured using video fluorescein angiography,...
In Brief Purpose: To compare visual acuity outcomes and diabetic retinopathy progression after pars plana vitrectomy (PPV) versus combined phacoemulsification (PPVCE) in patients with diabetes. Methods: Retrospective review of 222 consecutive undergoing PPV or PPVCE. Results: A total 251 eyes were evaluated (PPV = 122, PPVCE 129). Four-year follow-up was 64% (161 eyes). Overall, had better preoperative (PPVCE 20/80, 20/160, P 0.03). At 4-year follow-up, improved +22, +11 letters) compared...
VASCULAR catheterization is widely employed in diagnostic technics (angiography' sampling of blood, and recording blood pressure) therapeutic methods (implants artificial pacemakers intravenous intra–arterial drip infusions) . In diagnosis the catheter seldom left vessel for more than a few hours, but therapy it may remain up to several days. The most common serious complication brief as well prolonged vascular thromboembolism. Its frequency varies from series series, e.g., frequencies 1 per...
The cardioangiographic findings in 50 women 40-54 years of age were compared with those a series 69 men infarction recruited from the same catchment area and investigated according to principles. Women less often had left ventricular abnormalities than men; this difference was mainly confined patients non-Q wave infarction: There no prevalence among Q infarctions. No major sex found coronary abnormalities. Collaterals common men.
Purpose: To explore optical coherence tomography angiography (OCTA) quality and associated factors in multicenter clinical studies. Methods: OCTA scans were obtained from participants with diabetic retinopathy three DRCR Retina Network studies using the Optovue AngioVue ZEISS AngioPlex. Macular (3 × 3 mm 6 mm) optic nerve captured. Quality was assessed by Casey Reading Center. Scans considered "poor" if signal strength index (SSI) less than 55 (AngioVue) or 7 (AngioPlex) excess motion, media...
Importance The DRCR Retina Network Protocol AC showed no significant difference in visual acuity outcomes over 2 years between treatment with aflibercept monotherapy and bevacizumab first switching to for suboptimal response treating diabetic macular edema (DME). Understanding the estimated cost cost-effectiveness of these approaches is important. Objective To evaluate vs bevacizumab-first strategies DME treatment. Design, Setting, Participants This economic evaluation was a preplanned...
The dimension, contractility, and regional wall motion of the right left ventricles were scored on angiograms 13 patients with arrhythmogenic ventricular dysplasia. In 10 ventricle was enlarged, in eight contractility reduced, all but one patient there abnormalities ventricle. most common abnormality mild hypokinesia. There bulging or dyskinetic areas seven patients. Regional found five patients, two whom also had areas. reproducibility scores generally fair varied unexpectedly both within...
A DNA sequence encoding the chain of ricin toxin (RTA) from castor bean plant, Ricinus communis, was placed under GAL1 promoter control and transformed into Saccharomyces cerevisiae. Induction expression RTA lethal. This lethality basis for a selection mutations in which inactivated toxin. number mutant alleles encoded cross-reactive material were sequenced. Eight first nine RTAs studied showed single-amino-acid changes involving residues located proposed active-site cleft.
Implementation of multicenter and/or longitudinal studies requires an effective quality assurance program to identify trends, data inconsistencies and process variability results over time. The Diabetes Control Complications Trial (DCCT) the follow-up Epidemiology Interventions (EDIC) study represent 30 years collection among a cohort participants across 27 clinical centers. plan is overseen by Data Coordinating Center implemented centers central reading units. Each unit incorporates...