A5030449236- Intraocular Surgery and Lenses
- Retinal Diseases and Treatments
- Glaucoma and retinal disorders
- Corneal surgery and disorders
- Ophthalmology and Visual Impairment Studies
- Ocular Surface and Contact Lens
- Retinal and Optic Conditions
- Corneal Surgery and Treatments
- Retinal and Macular Surgery
- Retinal Imaging and Analysis
- Ocular Infections and Treatments
- Viral Infections and Immunology Research
- Ocular Diseases and Behçet’s Syndrome
- Ocular and Laser Science Research
- Connexins and lens biology
- Cardiac, Anesthesia and Surgical Outcomes
- Visual perception and processing mechanisms
- Health Systems, Economic Evaluations, Quality of Life
- Optical Coherence Tomography Applications
- Atrial Fibrillation Management and Outcomes
- Respiratory viral infections research
- Hepatitis Viruses Studies and Epidemiology
- Viral gastroenteritis research and epidemiology
- Retinal Development and Disorders
- Diabetes Management and Research
Retina Associates
2015-2024
Case Western Reserve University
1995-2021
Northeast Ohio Medical University
2021
Pittsburg State University
2020
Cleveland Clinic Lerner College of Medicine
2018
Mount Sinai Hospital
2017
University of Toronto
2017
Lunenfeld-Tanenbaum Research Institute
2017
University of Liverpool
1963-2016
King's College Hospital
2015
To study the clinical effectiveness of viscocanalostomy in a population black African patients with open-angle glaucoma that was uncontrolled on medical treatment.Department Ophthalmology, Medical University Southern Africa, Medunsa, South Africa.In this prospective performed 214 eyes 157 poorly controlled by therapy. The procedure involves production superficial and deep scleral flaps. flap is disserted to plane Schlemm's canal. From plane, an intact window Descemet's membrane created...
<h3>Objective</h3> To examine the persistence of original treatment effects 10 years after Diabetes Control and Complications Trial (DCCT) in follow-up Epidemiology Interventions (EDIC) study. In DCCT, intensive therapy aimed at near-normal glycemia reduced risk microvascular complications type 1 diabetes mellitus compared with conventional therapy. <h3>Methods</h3> Retinopathy was evaluated by fundus photography 1211 subjects EDIC year 10. Further 3-step progression on Early Treatment...
Significance Vascular complications are the main cause of morbidity and mortality in diabetic population. Clinical trials show a persistence benefit from early application intensive therapy for glycemic control patients, phenomenon referred to as metabolic memory. The mechanisms underlying memory not fully understood. In this study, using two groups type 1 patients with without development sets genomic DNAs collected 16–17 y apart same we showed persistency DNA methylation over time at key...
A collection of 44 cases malignancy in scars, chronic ulcers, and sinuses, included the following predisposing lesions: a 20-year-old sinus from ischial bursitis, 23-year-old bed sore, congenital gumma about 50 years old, three burn scars (average age scar 56 years), 11 sinuses osteomyelitis, 27 ulcers leg. The osteomyelitis two rapidly fatal sarcomas, one present for 16 years, other sinus. remaining tumours this group were squamous carcinomas that developed with an average duration 37...
OBJECTIVE Intensive treatment (INT) of type 1 diabetes reduces the incidence cardiovascular disease (CVD) events compared with conventional (CONV), but it also results in more weight gain. Our objective was to examine whether excessive gain from INT is independently associated subsequent CVD events. RESEARCH DESIGN AND METHODS Quartiles (Q) 1,213 participants aged 18 years and older at enrollment Diabetes Control Complications Trial (DCCT) were determined within randomized groups (INT vs....
Albino rabbits were treated four or six times daily with 1% prednisolone acetate, medroxyprogesterone a control vehicle, after one of three conditions. First, 3-mm linear perforating stromal incisions; drugs given for seven days, and wound bursting strength was determined. Prednisolone suppressed tensile by 20%; it 11%. Second, trephination, drug administration 14 days decreased collagen formation in the scar buttons 43% prednisolone-treated group 39% medroxy-progesterone-treated group....
Synthetic bradykinin WCM in;ected intraperitoneally to produce pain. The optimal individual dose of was given every 15 minutes for 120 after analgesic administration. experiments were performed double blind on groups 16 sub;ects (4 per drug) in a random block design. pain response recorded by the sub;ect pressing one four buttons signal box. Each button registered counter at rate second corresponding number; sum counts gave weighted score (WPS). latent period recorded; it triggered cutoff...
The purpose of this study was to evaluate the role corticosteroids in managing subfoveal choroidal neovascularization (CNV) secondary presumed ocular histoplasmosis syndrome. cases eighteen patients with histoplasmosis-related CNV treated were reviewed. Ten received oral prednisone for 4 6 weeks, and eight a single sub-Tenon's injection triamcinalone. Visual acuity outcomes analyzed along side effect profiles. At two-week follow-up, group showed median improvement Snellen visual +2.0 lines,...
SUMMARY It is now established that there a destructive biophysical interaction between plastic intraocular lens and the corneal endothelium during implantation. In present study, Na-hyaluronate was placed into anterior chamber of one eye 20 rabbits, after extraction prior to pseudophake implantation, in an attempt protect endothelium. The other each rabbit subjected implantation conventional manner. During 4-week postoperative period, it observed treated with showed significantly less edema...
In Brief Purpose: To determine safety and efficacy of intravitreal triamcinolone acetonide (IVTA) for refractory clinically significant diabetic macular edema (DME). Design: Prospective, randomized, dose-escalation pilot study comparing single injection 2 mg versus 4 doses IVTA. Methods: Inclusion criteria included DME persisting ≥3 months after maximal laser treatment visual acuity ≤20/40. Best-corrected ETDRS vision, intraocular pressure, presence DME, fluorescein angiography (FA) were...
In the summer of 1965 an epidemic aseptic meningitis and other acute febrile illness occurred in New Haven, Connecticut. The agent responsible proved to be echovirus 11-prime, a distantly related variant prototype Gregory strain echo-11, which has not heretofore been associated with community outbreak. age group attacked was unusual that more than half virus positive patients were under 6 months old. Other syndromes encountered, chiefly 1 4 year group, nonspecific illnesses respiratory...