- Dental Health and Care Utilization
- Mental Health Treatment and Access
- Schizophrenia research and treatment
- Chronic Disease Management Strategies
- Oral microbiology and periodontitis research
- Oral Health Pathology and Treatment
- Health Systems, Economic Evaluations, Quality of Life
- Health, psychology, and well-being
- Health, Medicine and Society
- Diabetes Management and Research
- Multiple Sclerosis Research Studies
- Healthcare Systems and Practices
- Art Therapy and Mental Health
- Healthcare Education and Workforce Issues
- Epigenetics and DNA Methylation
- Gout, Hyperuricemia, Uric Acid
- Pancreatic function and diabetes
- Patient Satisfaction in Healthcare
- Diabetes and associated disorders
- Paraoxonase enzyme and polymorphisms
- Maternal and Perinatal Health Interventions
- Health Education and Validation
- Community Health and Development
- Biochemical Acid Research Studies
- Reliability and Agreement in Measurement
Université de franche-comté
2011-2024
Université de Bourgogne
2022
Laboratoire de recherches Intégratives en Neurosciences et psychologie Cognitive
2019-2021
Université Clermont Auvergne
2021
Université Bourgogne Franche-Comté
2021
Centre Hospitalier Universitaire de Besançon
2021
Laboratoire de Neurosciences Cognitives
2021
Cleveland Clinic Lerner College of Medicine
2018
University of Washington
2017
Inserm
1993-1997
Significance Vascular complications are the main cause of morbidity and mortality in diabetic population. Clinical trials show a persistence benefit from early application intensive therapy for glycemic control patients, phenomenon referred to as metabolic memory. The mechanisms underlying memory not fully understood. In this study, using two groups type 1 patients with without development sets genomic DNAs collected 16–17 y apart same we showed persistency DNA methylation over time at key...
OBJECTIVE Intensive treatment (INT) of type 1 diabetes reduces the incidence cardiovascular disease (CVD) events compared with conventional (CONV), but it also results in more weight gain. Our objective was to examine whether excessive gain from INT is independently associated subsequent CVD events. RESEARCH DESIGN AND METHODS Quartiles (Q) 1,213 participants aged 18 years and older at enrollment Diabetes Control Complications Trial (DCCT) were determined within randomized groups (INT vs....
The "General Oral Health Assessment Index" (GOHAI) was widely used in clinical or epidemiological studies worldwide, as it available for use different languages. Therefore, the aim of this study to evaluate psychometric characteristics GOHAI a representative sample patients with schizophrenia. A total 90 schizophrenic (in-patients and out-patients) were recruited from participants "buccodor study" (NCT02167724) between March September 2015. They selected using random stratified sampling...
In a postal study we used the Nottingham Health Profile questionnaire to assess quality of life elderly survivors open-heart surgery. From January 1984 October 1993, 146 patients over 75 years age underwent surgery in Department Cardiovascular Surgery at Beasançon (France). Eleven (7. 5%) died immediate post-operative course. Patients' mean follow-up was 3.4 +/- 2.4 years. Fourteen during follow-up. One hundred and four completed questionnaires were returned. Five per cent lived an old...
Our study aimed to explore the views and experiences in oral health oral-health-related quality of life (OHRQoL) persons with schizophrenia (PWS) order expand understanding factors that either limit or facilitate their healthcare pathway, which can ultimately optimize and/or OHRQoL. A qualitative was conducted France Côte d'Or department (530 000 habitants) centered on PWS's perceived meanings regarding OHRQoL, semi-structured individual interviews were used. conventional content analysis...
Abstract Objective The aim of this study was to explore, in a sample population people with schizophrenia (PWS), the role anticholinergic burden on perception oral health-related quality life (OHrQoL) France. Methods A pilot performed between March 2014 and January 2016. PWS were recruited from Côte d’Or department Dental status investigated using Decayed, Missing, or Filled Teeth (DMFT) index, Xerostomia Index (XI), Global Oral Health Assessment (GOHAI) for OHrQoL. impregnation score...
Abstract Background The aim of this study was to test the General Oral Health Assessment Index Questionnaire (GOHAI) items for differential item functioning (DIF) according demographic characteristics (gender, age) and mental health status (schizophrenic disorders versus general population) using Rasch analysis. Methods This is a cross-sectional aggregated baseline data from validation GOHAI in French population (GP) similar persons with schizophrenia (PWS). DIF tested Partial Credit Model....
Abstract Background The aim of this study was to present the different stages development Schizophrenia Oral Health Profile (SOHP) questionnaire, aimed at assessing oral disorders and their impacts on functioning psychosocial wellbeing for patients with schizophrenia (PWS) give results a feasibility conducted in France Materials methods first step qualitative semi-structured interviews were 20 PWS 6 health professionals (HP). A focus group integrating 4 HP also organised identify items SOHP....
Persons with schizophrenia are particularity susceptible to poor oral health. Symptoms of often affect health behaviors and lifestyle. The aim was explore coping strategies used by people in order understand best involve them the management their own daily life.This is systematic review reported accordance Preferred Reporting Items for Systematic Reviews Meta-Analyses (PRISMA) statements. We included cross-sectional longitudinal quantitative qualitative studies that 1) examined regarding...
Abstract Background The aim of this work was to present the creation appropriate tools evaluate coping strategies in Oral-Health-related Quality Life (OHrQOL) implemented by persons with schizophrenia (PWS), Schizophrenia Coping Oral Health Profile (SCOOHP), and results a feasibility study. Methods A qualitative investigation conducted between June 2016 May 2017. first step included 26 semi-structured individual interviews, 20 PWS 6 health professionals (HPs), 2 focus groups (PWS HPs)...
Implementation of multicenter and/or longitudinal studies requires an effective quality assurance program to identify trends, data inconsistencies and process variability results over time. The Diabetes Control Complications Trial (DCCT) the follow-up Epidemiology Interventions (EDIC) study represent 30 years collection among a cohort participants across 27 clinical centers. plan is overseen by Data Coordinating Center implemented centers central reading units. Each unit incorporates...
Background Hyperglycemia leading to increased oxidative stress is implicated in the risk for development of macrovascular and microvascular complications patients with type 1 diabetes mellitus. Methods Results A random subcohort 349 participants was selected from DCCT / EDIC (Diabetes Control Complications Trial/Epidemiology Diabetes Interventions Complications) cohort. This included 320 controls 29 cardiovascular disease cases that were augmented 98 additional known yield a case cohort 447...
Relapses are particularly stressful for patients with multiple sclerosis (MS). The impact of relapses on the quality life (QoL) has been described in literature. Several QoL scales have already validated MS. However, none them focuses specifically how perceive relapse periods. objective this research was to establish a self-questionnaire evaluate related MS and relapses: PERSEPP scale. This scale is based individual semidirective interviews relapsing-remitting form MS, health workers, focus...
The Schizophrenia Oral Health Profile questionnaire was developed to assess the oral health-related quality of life among individuals with schizophrenia based on their perceptions rather than from caregivers. A 5-point Likert scale used self-report 42 items. In present study, different analyses were conducted determine dimensional structure final scale: (1) inter-item correlation analysis and Cronbach's α coefficient, (2) Rasch model analysis, (3) exploratory factor (4) confirmatory...
Abstract Background: The objective of this study (registered under number 2020 006) was to assess the internal consistency revised Mental Health Professional Culture Inventory (MHPCI) scale, which comprises 15 items, among mental health service workers in Romania. Methods: To examine psychometric properties MHPCI questionnaire within Romanian population, we employed two main methods: partial credit model (PCM) and Exploratory factor analysis (EFA). Results: A total 94 individuals were...
Background The MAKASI intervention aimed to empower sub-Saharan immigrants living in the Paris metropolitan area regarding sexual health and reduce their HIV exposure. was developed based upon a theoretical model of individual empowerment.Purpose A scale using sixteen 4-point Likert items adapted from existing tools measure HIV/AIDS empowerment as an outcome. This study describes psychometric validation this scale.Methods Data 433 participants were used. Construct validity internal...