Mark Phillips
A5046721910- Meta-analysis and systematic reviews
- Health Systems, Economic Evaluations, Quality of Life
- Glaucoma and retinal disorders
- Retinal Diseases and Treatments
- Shoulder Injury and Treatment
- Total Knee Arthroplasty Outcomes
- Retinal Imaging and Analysis
- Bone fractures and treatments
- Osteoarthritis Treatment and Mechanisms
- Orthopaedic implants and arthroplasty
- Clinical practice guidelines implementation
- Orthopedic Surgery and Rehabilitation
- Hip disorders and treatments
- Knee injuries and reconstruction techniques
- Diabetes Management and Research
- Intraocular Surgery and Lenses
- Retinal and Macular Surgery
- Spine and Intervertebral Disc Pathology
- Hip and Femur Fractures
- Statistical Methods in Clinical Trials
- Cardiac, Anesthesia and Surgical Outcomes
- Sports injuries and prevention
- COVID-19 and healthcare impacts
- Spinal Fractures and Fixation Techniques
- Deception detection and forensic psychology
McMaster University
2016-2025
Impact
2019-2024
Impact Technology Development (United States)
2024
Cambridge University Hospitals NHS Foundation Trust
2023
Addenbrooke's Hospital
2023
University of Ottawa
2023
University Hospital of Wales
2022
Cardiff University
2022
Marymount University
2021
Candid
2021
<h3>Objective</h3> To examine the persistence of original treatment effects 10 years after Diabetes Control and Complications Trial (DCCT) in follow-up Epidemiology Interventions (EDIC) study. In DCCT, intensive therapy aimed at near-normal glycemia reduced risk microvascular complications type 1 diabetes mellitus compared with conventional therapy. <h3>Methods</h3> Retinopathy was evaluated by fundus photography 1211 subjects EDIC year 10. Further 3-step progression on Early Treatment...
Significance Vascular complications are the main cause of morbidity and mortality in diabetic population. Clinical trials show a persistence benefit from early application intensive therapy for glycemic control patients, phenomenon referred to as metabolic memory. The mechanisms underlying memory not fully understood. In this study, using two groups type 1 patients with without development sets genomic DNAs collected 16–17 y apart same we showed persistency DNA methylation over time at key...
To develop an instrument to evaluate the credibility of anchor based minimal important differences (MIDs) for outcome measures reported by patients, and assess reliability instrument.Instrument development study.Initial criteria were developed evaluating MIDs on a literature review (Medline, Embase, CINAHL, PsycInfo databases) experience authors in methodology estimation MIDs. Iterative discussions team pilot testing with experts potential users facilitated final instrument.With newly...
A prospective clinical study used joint scintigraphy to investigate conservative treatment of juvenile osteochondritis dissecans (JOCD) the femoral condyle. The predictive value scintigraphic evaluation and various parameters (age at onset, sex, location size lesion) were analyzed. Over a 10 year period, senior author followed 92 knees in 76 patients, 60 whom male 16 female (11 5 bilaterals, respectively). All patients participants athletics or exercise programs. had orthopaedic assessment,...
OBJECTIVE Intensive treatment (INT) of type 1 diabetes reduces the incidence cardiovascular disease (CVD) events compared with conventional (CONV), but it also results in more weight gain. Our objective was to examine whether excessive gain from INT is independently associated subsequent CVD events. RESEARCH DESIGN AND METHODS Quartiles (Q) 1,213 participants aged 18 years and older at enrollment Diabetes Control Complications Trial (DCCT) were determined within randomized groups (INT vs....
The novel coronavirus disease 2019 (COVID-19) pandemic has now surpassed 1 million documented cases globally. forced social distancing measures and cancellation of nonessential services at an unprecedented scale. COVID-19, caused by the viral pathogen severe acute respiratory syndrome 2 (SARS-CoV-2), permeated communities unparalleled rates. Within just a few months after initial documentation in December 2019, World Health Organization (WHO) declared pandemic. Prior to this, however, WHO...
This experiment examined whether a photoarray administrator's knowledge of suspect's identity increased false identification rates. Fifty participant-administrators (PAs) presented 50 participant-witnesses (PWs) two perpetrator-absent photoarrays following live staged crime involving perpetrators. For one per trial, the experimenter revealed to PA. Each PA sequentially or simultaneously in presence absence an observer. When observer was present, had biasing effect sequential only. pattern...