- Bacterial Identification and Susceptibility Testing
- Antibiotic Use and Resistance
- Antimicrobial Resistance in Staphylococcus
- Antibiotics Pharmacokinetics and Efficacy
- Antibiotic Resistance in Bacteria
- Patient Satisfaction in Healthcare
- Infections and bacterial resistance
- Facial Rejuvenation and Surgery Techniques
- Influenza Virus Research Studies
- Respiratory viral infections research
- Antifungal resistance and susceptibility
- Streptococcal Infections and Treatments
- Infective Endocarditis Diagnosis and Management
- Pharmaceutical industry and healthcare
- Bacterial biofilms and quorum sensing
- Pneumonia and Respiratory Infections
- Body Contouring and Surgery
- Neutropenia and Cancer Infections
- Platelet Disorders and Treatments
- Nosocomial Infections in ICU
- Fungal Infections and Studies
- Inflammatory Myopathies and Dermatomyositis
- Nail Diseases and Treatments
- Pharmaceutical Practices and Patient Outcomes
Advocate Lutheran General Hospital
2019-2023
Cleveland Clinic
2022
The Ohio State University Wexner Medical Center
2017-2021
Advocate Illinois Masonic Medical Center
2020
Advocate South Suburban Hospital
2020
Advocate Trinity Hospital
2020
Swedish Covenant Hospital
2020
Advocate Christ Medical Center
2020
Advocate Good Samaritan Hospital
2019
Advocate Health Care
2018
Abstract Candida auris is an emerging fungal pathogen that typically resistant to fluconazole and known cause healthcare-associated outbreaks. We retrospectively reviewed 28 patients who had >1 positive culture for C. within a multisite health system in Illinois, USA, during May 2018–April 2019. Twelve of these were treated as inpatients infections; 10 (83%) met criteria clinical success, defined absence all-cause mortality, recurrence, infection-related readmission at 30 days from the first...
Objective Oritavancin is a lipoglycopeptide antibiotic approved for use in acute bacterial skin and structure infections as single 1200‐mg parenteral dose. Because of oritavancin's long half‐life broad gram‐positive activity, interest its other high. Methods This study retrospective cohort evaluation patients receiving oritavancin at academic medical center. All more than one dose were included. Patients excluded if therapy was interrupted by 14 days. Efficacy, defined priori clinical...
The author performs gluteal augmentation by inserting implants into subfascial pockets after using templates and sizers to determine implant size. He reports that this technique yields good projection, is easily reproducible, provides predictable results.
BackgroundStaphylococcus aureus bacteraemia (SAB) carries high rates of morbidity and mortality. Antimicrobial stewardship programmes (ASPs) are well situated to promote adherence quality performance measures in order optimize the management SAB associated clinical outcomes.
Stenotrophomonas maltophilia is intrinsically resistant to several antibiotics, making it potentially challenging treat. Studies have demonstrated treatment failures and resistance development with monotherapy (MT); however, clinical data are limited combination therapy (CT).To compare outcomes CT versus MT for S. pneumonia.This was a retrospective cohort study of patients admitted between November 2011 October 2017 pneumonia who received at least 48 h effective therapy. The primary outcome...
Fluoroquinolones (FQs) are often preferred as oral step-down therapy for bloodstream infections (BSIs) due to favorable pharmacokinetic parameters; however, they also associated with serious adverse events. The objective of this study was compare clinical outcomes patients who received an FQ versus beta-lactam (BL) uncomplicated streptococcal BSIs. This multicenter, retrospective cohort analyzed adult completed or BL at least one blood culture positive a Streptococcus species from 1 January...
The purpose of this study was to evaluate the impact infectious diseases consultation (IDC) and a real-time antimicrobial stewardship (AMS) review on management Staphylococcus aureus bacteremia (SAB).This retrospective included adult inpatients with SAB from January 2016 December 2018 at 7 hospitals. Outcomes were compared between 3 time periods: before mandatory IDC AMS (period 1), after 2), 3). primary outcome bundle adherence, defined as appropriate intravenous therapy, duration...
OBJECTIVE To characterize the top 1% of inpatients who contributed to 6-month antimicrobial budget in a tertiary, academic medical center and identify cost-effective intervention opportunities targeting high-cost utilization. DESIGN Retrospective cohort study. PATIENTS Top from July 1 through December 31, 2014. METHODS Patients were identified pharmacy billing database. Baseline characteristics collected retrospective chart review. presented stewardship team determine appropriate utilization...
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Abstract Background Infectious diseases consult (IDC) and antimicrobial stewardship (AMS) intervention independently demonstrate improved management of Staphylococcus aureus bacteremia (SAB). However, data supporting utilizing both strategies is limited. The objective the current study to assess evidence-based bundle adherence for SAB in presence absence mandatory IDC AMS pharmacist review a multi-site health system. Methods This retrospective included adult inpatients with from January 2016...
Abstract Background Recent literature suggests that AmpC production may be overcalled in Enterobacterales, leading to unnecessary broad-spectrum antimicrobial utilization. The Infectious Diseases Society of America (IDSA) has since reassessed classification high and low risk organisms with inducible expression. With this updated guidance, our health system approved changes microbiology reporting producers an effort guide prescribing appropriate antibiotics. primary objective project was...
Results.In 2013, >1 antibiotic dose/day was prescribed to 16.2% of VA dental patients (total = 476,451 patients).By class, aminopenicillins were most frequently (69.4%), followed by lincomycins (21.9%).The overall mean AD 11.4 (range 1-309) days and DOT 11.5 (1-309).Of the Veterans who received an from a dentist, only 2.3% broad-spectrum agent.However, (15.0) significantly longer than narrow spectrum (11.2;P < 0.0001). Conclusion.While prevalence prescribing low, patient-level duration...
Stenotrophomonas maltophilia is an emerging nosocomial pathogen with intrinsic resistance to several antibiotics, making it potentially challenging treat. Studies have demonstrated treatment failures and development monotherapy (MT); however, limited clinical data improved outcomes combination therapy (CT). The aim of this study was compare CT vs. MT for S. pneumonia. This a retrospective cohort patients admitted OSUWMC between November 2011 October 2017 pneumonia who received at least 48...
Abstract Background The Clinical and Laboratory Standards Institute (CLSI) lowered the minimum inhibitory concentration (MIC) breakpoints of various β-lactam antimicrobials eliminating need for confirmatory testing extended-spectrum β-lactamase (ESBL) organisms. Our institution adopted new CLSI in June 2015. This multi-site study assessed impact laboratory cessation ESBL reporting on MIC distribution commonly used clinical outcomes. Methods retrospective included adult inpatients with...