A5027713656- Ocular Diseases and Behçet’s Syndrome
- Retinal and Optic Conditions
- Urinary Tract Infections Management
- Antibiotic Use and Resistance
- COVID-19 epidemiological studies
- COVID-19 and healthcare impacts
- Healthcare Systems and Reforms
- Surgical site infection prevention
- Cardiac, Anesthesia and Surgical Outcomes
- Extracellular vesicles in disease
- COVID-19 Digital Contact Tracing
- Urinary Bladder and Prostate Research
- Ethics and bioethics in healthcare
- Antifungal resistance and susceptibility
- Retinal Diseases and Treatments
- Bacterial Identification and Susceptibility Testing
- Pelvic and Acetabular Injuries
- Otitis Media and Relapsing Polychondritis
- Ophthalmology and Eye Disorders
- Nosocomial Infections in ICU
- Plant Pathogenic Bacteria Studies
- Systemic Sclerosis and Related Diseases
- Influenza Virus Research Studies
- Pressure Ulcer Prevention and Management
- Clostridium difficile and Clostridium perfringens research
Ministry of Health
2023
Tan Tock Seng Hospital
2016-2022
NorthShore University HealthSystem
2018-2020
Evanston Hospital
2020
Singapore National Eye Center
2017
Royal Devon & Exeter NHS Foundation Trust
2017
Biology of Infection
2017
Engineering Associates (United States)
2017
Fraser Health
2017
West Suburban Medical Center
2016
OBJECTIVE To determine the source of a healthcare-associated outbreak Pantoea agglomerans bloodstream infections. DESIGN Epidemiologic investigation outbreak. SETTING Oncology clinic (clinic A). METHODS Cases were defined as isolation from blood or catheter tip cultures A patients during July 2012–May 2013. Clinic medical charts and laboratory records reviewed; infection prevention practices facility’s water system evaluated. Environmental samples collected for culture. Clinical...
Background: In delivering resident-centered integrated care, it is imperative to understand our residents’ unique health needs. We present the approach adopted by Central Health, an regional network responsible for of a population 1.5 million in central Singapore, utilize diverse data sources constructing comprehensive profile, and its translation strategy planning. Methods: harnessed from multiple sources, including government statistics, national-level surveys, hospital electronic medical...
Myelin Regulatory Factor (MYRF) regulates retinal pigment epithelial (RPE) development and variants in the C-terminus are linked to isolated nanophthalmos, while loss-of-function cause syndromic disease. To define molecular mechanism of this discrepancy, vitro animal studies were performed on a pathogenic C-terminal variant (p.Gly1126fs30* or dG-MYRF). ARPE-19 cells transduced with dG-MYRF revealed reduced target gene expression compared WT-MYRF, steady state levels MYRF cleavage product,...
The purpose of this study is to evaluate the spectrum scleritis from database Ocular Autoimmune Systemic Inflammatory Infectious Study (OASIS) at a tertiary eye referral institute in Singapore. Clinical records 120 patients with 2200 were reviewed.56.6% females, mean age 48.6 ± 15.9 years. 75 (62.5%) had diffuse anterior scleritis, 25 (20.8%) nodular 7 (5.8%) necrotizing and 13 (10.8%) posterior scleritis. complications observed 53.3% patients, including uveitis (42.5%), raised intraocular...
To report the pattern of posterior and panuveitis at a tertiary referral center in Singapore.Subgroup retrospective analysis 334 new cases, from Ocular Autoimmune Systemic Inflammatory Infectious Study (OASIS) database. Descriptive was performed visual outcome complications were reported.The etiology for uveitis infectious 162 patients (48.5%), non-infectious 144 (43.1%), idiopathic 28 (8.4%). More with bilateral disease had (n = 82, 50.9%) (p 0.012). The most common complication epiretinal...
Rostered routine testing for severe acute respiratory coronavirus virus 2 (SARS-CoV-2) infection among healthcare personnel—Is there a role in tertiary-care hospital with enhanced prevention and control measures robust sickness-surveillance systems? - Volume 43 Issue 10
Tuberculosis (TB) remains a major global health burden and has both pulmonary extra-pulmonary manifestations. One well-recognised complex form is ocular TB, with its diverse extra- intra-ocular presentations often without signs of systemic illness. These could be caused directly by Mycobacterium tuberculosis inflammation or represent delayed immune response. Epidemiological data on the true prevalence TB scanty varied in different parts world. This due to lack uniform diagnostic criteria as...
AIM: To report the change in visual acuity and central macular thickness (CMT) following treatment with intravitreal aflibercept injections patients neovascular age-related degeneration (nAMD) suboptimum response to ranibizumab. METHODS: This was a retrospective study. The inclusion criteria were nAMD who responded poorly Patients then received either 3 consecutive followed by PRN or alone. Primary endpoints mean best-corrected (BCVA) CMT at 12mo. Secondary number of adverse events. RESULTS:...
Background Clostridioides difficile Infection (CDI) is a persistent healthcare issue. In the US, CDI most common infectious cause of hospital-onset (HO) diarrhea. Objective Assess impact admission testing for toxigenic C. colonization on incidence HO-CDI. Design Pragmatic stepped-wedge Control initiative. Setting NorthShore University HealthSystem four-hospital system near Chicago, IL. Patients All patients admitted to four hospitals during Interventions From September 2017 through August...
# Process mapping as a framework for performance improvement in emergency general surgery {#article-title-2} Emergency conditions are often thought of being too acute and unpredictable the development standardized approaches to quality (QI). However, process
An abstract is not available for this content so a preview has been provided. As you have access to content, full PDF via the ‘Save PDF’ action button.
Abstract Background Catheter-associated urinary tract infections (CAUTIs) are among the most common healthcare-associated infections. Many patients at our institution with a CAUTI do not have signs or symptoms of infection and bacterial growth likely represents asymptomatic bacteriuria (ASB). As result, we implemented Modified Lab Workflow (MLW) focused on diagnostic stewardship to improve urine culture (UCx) reporting prevent misclassification unnecessary treatment CAUTIs. Methods On Sep....
Background / Objective: Governance and Leadership Subsystem (GLS) of health systems governs but also directs Service Delivery (SDS) transformation. Performance management (PM) is a key GLS activity. Coherent PM frameworks improve SDS governance, system performance ultimately population outcomes.
 Yishun Health (YH) an integrated care organization within National Healthcare Group (NHG) caring for 320,000 residents in northern Singapore as the Zone Regional Population System (YZ). YH...
Surveillance for asymptomatic carriage of multidrug-resistant (MDR) pathogens is useful to determine the burden these organisms and help guide infection prevention strategy. We currently perform surveillance cultures Gram-negative (GNMDR) in ICUs on a monthly basis. added quarterly point prevalence survey all hospital units other key over one year whether our program should expand beyond ICU include organisms. Rectal samples were collected 1 starting June 2016 at NorthShore University...
Abstract Background A majority of healthcare-associated urinary tract infections (UTIs) are caused by the use catheters (CAUTI). Finding bacteriuria is common in catheterized patients and often leads to unnecessary antibiotic treatment, increased length stay additional healthcare costs. We implemented an innovative intervention improve urine culture (UCx) orders prevent overdiagnosis CAUTIs. Methods Orders for UCx adult with short-term at NorthShore University HealthSystem, IL were reviewed...
Background: Catheter-associated urinary tract infections (CAUTIs) account for >15% of hospital-acquired infections, resulting in increased length stay and costs. Consequently, methods to improve indwelling catheter (IUC) care maintenance are warranted reduce the risk CAUTIs. This study was a prospective quality improvement (QI) project CAUTIs using prepackaged cloths (ReadyCleanse by Medline Industries) simple, standardized cleaning process IUCs. Methods: is an ongoing QI at NorthShore...
Background: Candida auris prevalence in Illinois, particularly the metropolitan Chicago area, is high. The Illinois Department of Public Health recommends empiric contact precautions for patients with a tracheostomy or requiring mechanical ventilation from skilled nursing facilities (vSNFs) long-term acute-care hospitals (LTACHs) who are admitted to an hospital. Cases C. infection and colonization reportable Extensively Drug Resistant Organism Registry (XDRO Registry). NorthShore University...