- Airway Management and Intubation Techniques
- Tracheal and airway disorders
- Respiratory Support and Mechanisms
- Cardiac Arrest and Resuscitation
- Neuropeptides and Animal Physiology
- Obstructive Sleep Apnea Research
- Hemostasis and retained surgical items
- Wound Healing and Treatments
- Cardiac Valve Diseases and Treatments
- Cardiac Structural Anomalies and Repair
- High Altitude and Hypoxia
- Anesthesia and Sedative Agents
- Organ Transplantation Techniques and Outcomes
- Mechanical Circulatory Support Devices
- Anesthesia and Pain Management
- Pain Mechanisms and Treatments
- Blood Pressure and Hypertension Studies
- Pharmacological Receptor Mechanisms and Effects
- Heart Rate Variability and Autonomic Control
- Cancer, Stress, Anesthesia, and Immune Response
- Surgical Sutures and Adhesives
- Cardiovascular Health and Disease Prevention
- Anesthesia and Neurotoxicity Research
- Macrophage Migration Inhibitory Factor
- Cardiac, Anesthesia and Surgical Outcomes
Guangzhou University
2022-2023
Guangxi University
2023
Bridge University
2023
Sun Yat-sen University
2022-2023
Sun Yat-sen Memorial Hospital
2022
Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital
2016-2021
University of Electronic Science and Technology of China
2018-2021
Chinese Academy of Sciences
2021
Icahn School of Medicine at Mount Sinai
2018
Sichuan University
2005-2016
Abstract The failure of wound healing is majorly attributed to uncontrolled bleeding and bacterial infections. However, developing a plaster that can stop bleeding, resist blood extravasation, realize directional transportation drugs promote remains significant challenge. Herein, superhydrophilic/hydrophobic polyvinyl alcohol/chitosan/silver@Thermoplastic polyurethane (PVA/CS/Ag@TPU) Janus membrane with structural wettability gradients developed. In this newly developed membrane, water...
MicroRNAs play a key role in neuropathic pain. In previous study, miR-190a-5p was significantly downregulated diabetic pain (DNP). However, the and pathological mechanism of DNP still remain unclear.DNP model established. The paw withdrawal thresholds were measured to assess mechanical nociceptive response. Dual-luciferase reporter assay used confirm target gene microRNA. expressions microRNA, gene, protein detected by quantitative real-time polymerase chain reaction or Western blot. levels...
The incidence of subarachnoid hemorrhage (SAH) and hazard ratio death increase with age. Overactivation microglia contributes to brain damage. This study aimed investigate the effects A3 adenosine receptors (A3R) activation on neurofunction microglial phenotype polarization in context SAH aged rats. A3R agonist (CI-IB-MECA) antagonist (MRS1523) were used model. Microglia cultured mimic presence or absence CI-IB-MECA and/or siRNA for A3R. status evaluated. P38 inhibitor SB202190 STAT6...
Abstract Background This retrospective study aimed to compare the clinical outcomes of parturients with placenta previa (PP) and accreta (PA) according their severity, when they were managed intraoperative abdominal aortic balloon occlusion (IAABO) during cesarean section. Methods We retrospectively examined 57 cases PP suspicion for PA in which IAABO was performed section between April 2014 June 2016. Based on preoperative examination risk factors, patients divided into low group high...
Summary Background The pediatric‐sized Streamlined Liner of Pharyngeal Airway ™ ( SLIPA ) is a new supraglottic airway device for children. Aims aim this study was to compare the clinical performance with Laryngeal Mask Airway‐Unique in paralyzed children under positive pressure‐controlled ventilation PCV ). Methods One hundred children, aged 2 months 12 years American Society Anesthesiologists physical status I–II were enrolled and randomly allocated group or (50 patients each group)....
Macrophages are involved in inflammatory responses and play a crucial role aggravating ventricular arrhythmias (VAs) after myocardial infarction (MI). Macrophage migration inhibitory factor (MIF) participates during acute MI. In the present study, we hypothesized that knockout (KO) of MIF may prevent VAs phase MI by inhibiting macrophage-derived pro-inflammatory mediators.We demonstrated MIF-KO mice mouse model exhibited significant decrease susceptibility to both vivo (84.6% vs 40.7%, P <...
This study aimed to explore the sensitivity and specificity an approach confirm depth of endotracheal tube. It was a prospective, diagnostic (Registration number: chiCTR-TRC-14005170) conducted in Department Anesthesiology West China Hospital. A total 100 patients underwent general anesthesia were included. The distance between upper margin cuff manubriosternal joint (CM) carina (CC) measured. accuracy confirmed against fiberoptic bronchoscopy (FOB) evaluated. Sensitivity, specificity,...
Continuously monitoring patient's cardiac performance during anesthesia induction and intubations is significant essential in order to control the risk of intubations, because almost all anesthetic agents decrease myocardial loading conditions contractility, bring reversible irreversible ischemic damage. A noninvasive, high benefit/cost ratio, easy operating continuous function evaluation still demand clinical system. Although phonocardiography could be a promising alternative tool, impact...
Wang, Man, Mengxue Liu, Jia Huang, Dan Fan, Shengzhong Tao Yu, Keli Xinchuan Wei, and Qian Lei. Long-term high-altitude exposure does not increase the incidence of atrial fibrillation associated with organic heart diseases. High Alt Med Biol. 22:285–292, 2021. Background: Atrial (AF) is one most common arrhythmias several complications following cardiac surgery. However, differences in AF diseases between highland lowland populations have been comprehensively studied. Methods: In this...
<title>Abstract</title> Chronic stress deficits social behaviors which involve malfunction of dentate gyrus (DG). However, the exact molecular mechanism and/or neural circuit DG participated in impairments induced by chronic is largely unknown. Here, we report that sodium leak channel (NALCN) reduction dorsal (dDG) but not ventral (vDG) induces deficit through lowering excitability and firings glutamatergic neurons. Furthermore, reveal medial septum (MS) an important downstream projection...
Cormack classification is believed as a golden indicator for predicting tracheal intubation difficult or not in clinic. Some anaesthetists usually estimate the airway state by examining single features. However, specialists agree that prediction accuracy of may be improved if multiple static and dynamic metrical features were considered. In this paper, we developed medical decision support system based on multilayer perceptron network Cormark predication with 13 input A database consisting...
Heart surgery in patients from high-altitude areas is more challenging than usual. Few studies have been published on this issue, and none of them discussed the effect an altitude change (from high to low altitude) a patient’s physiology or its effects perioperative management. Here, we present case 46-year-old man who was long-time resident Tibetan area Sichuan (altitude >3000 m) underwent Stanford type A aortic dissection emergency plain. Anesthetic management occurred through...