- Biofuel production and bioconversion
- Microbial Metabolic Engineering and Bioproduction
- Plant-Microbe Interactions and Immunity
- Genomics and Phylogenetic Studies
- Legume Nitrogen Fixing Symbiosis
- Plant Pathogenic Bacteria Studies
- Adsorption and biosorption for pollutant removal
- bioluminescence and chemiluminescence research
- Microbial Community Ecology and Physiology
- Polysaccharides and Plant Cell Walls
- Fungal and yeast genetics research
- Polyamine Metabolism and Applications
- Renal function and acid-base balance
- Cancer Immunotherapy and Biomarkers
- Advanced Fluorescence Microscopy Techniques
- Microbial bioremediation and biosurfactants
- Poisoning and overdose treatments
- Bacteriophages and microbial interactions
- Protist diversity and phylogeny
- Diet, Metabolism, and Disease
- Biocrusts and Microbial Ecology
- Liver Disease Diagnosis and Treatment
- Cancer Research and Treatments
- Enzyme Production and Characterization
- Lignin and Wood Chemistry
Hebei General Hospital
2025
Northwest A&F University
2011-2024
Henan Provincial People's Hospital
2021
Henan University
2021
Zhengzhou University
2021
Jilin University
2016
Union Hospital
2016
Abstract Background Bioconversion of plant biomass into biofuels and bio-products produces large amounts lignin. The aromatic biopolymers need to be degraded before being converted value-added bio-products. Microbes can environment-friendly efficiently degrade Compared fungi, bacteria have some advantages in lignin degradation, including broad tolerance pH, temperature, oxygen the toolkit for genetic manipulation. Results Our previous study isolated a novel ligninolytic bacterial strain...
In the present study, we evaluated a bacterium that was isolated from waste water for its ability to take up cadmium and manganese. The strain, identified both biochemically by 16S rRNA gene sequence as Klebsiella, named Yangling I2 found be highly resistant heavy metals. Surface characterization of via SEM revealed gross morphological changes, with cells appearing biconcave discs after metal exposure rather than their typical rod shape. effects pH, temperature, concentration, agitation...
Esophageal squamous cell carcinoma (ESCC) is a prevalent and aggressive malignancy, often diagnosed at an advanced stage with poor prognosis. This case report highlights the successful treatment of patient ESCC, who presented bilateral lung adrenal gland metastases. Despite nature disease, underwent regimen first-line chemotherapy combined immunotherapy, followed by immune maintenance therapy. Remarkably, achieved complete remission after completion treatment, demonstrating potential...
Polyvinyl alcohol (PVA) is used widely in industry, and associated environmental pollution a serious problem. Herein, we report novel, efficient PVA degrader, Stenotrophomonas rhizophila QL-P4, isolated from fallen leaves virgin forest the Qinling Mountains. The complete genome was obtained using single-molecule real-time (SMRT) technology corrected Illumina sequencing. Bioinformatics analysis revealed eight PVA/vinyl oligomer (OVA)-degrading genes. Of these, seven genes were predicted to be...
Aims: Eukaryotic typical 2-cysteine (Cys) peroxiredoxins (Prxs) are multifunctional proteins subjected to complex regulation and play important roles in oxidative stress resistance, hydrogen peroxide (H2O2) signaling modulation, aging, cancer, but the information on biochemical functions mechanisms of prokaryotic atypical 2-Cys Prxs is largely lacking. Results: In this study, we show that at low concentrations, Prx Corynebacterium glutamicum (CgPrx) mainly exists as monomers displays...
A Gram-staining-negative, rod-shaped, strictly aerobic, non-motile, non-spore-forming, orange bacterium, which was designated strain YL28-9T, isolated from sandy soil in the district of Yulin, Shaanxi province, PR China, and characterized by using a polyphasic taxonomic approach. The optimal growth conditions were 30 °C, pH 7.0, 0 % (w/v) NaCl. Phylogenetic analysis, based on 16S rRNA gene sequence, revealed that YL28-9T represented member genus Pedobacter showed highest sequence similarity...
It has been demonstrated that drying can significantly promote the antioxidant active substances of fresh walnut, as well enhance lipid content and conversion glycerol phospholipids to lysophospholipids in walnut. Currently, oven (OD) natural air (NAD) are two most commonly used methods for However, differences their effects on quality final product remain unclear. This study investigated effect OD NAD phenotypic physiological properties oxidation four main walnut varieties W10, W179, W185,...
Protein-protein interactions are important for virtually every biological process, and a number of elegant approaches have been designed to detect evaluate such interactions. However, few these methods allow the detection dynamic real-time protein-protein in bacteria. Here we describe bioluminescence resonance energy transfer (BRET) system based on bacterial luciferase LuxAB. We found that enhanced yellow fluorescent protein (eYFP) accepts emission from LuxAB emits fluorescence. Importantly,...
Abstract Plants secrete sugars from their roots into the soil, presumably to support beneficial plant‐microbe interactions. Accordingly, manipulation of sugar secretion might be a viable strategy enhance plant health and productivity. To evaluate effect increased root on performance soil microbiome, we overexpressed glucose sucrose‐specific membrane transporters in epidermal cells model Arabidopsis thaliana . These plants showed strongly rates hydroponic culture system. When grown...
Filamentous fungi are intensively used for producing industrial enzymes, including lignocellulases. Employing insoluble cellulose to induce the production of lignocellulases causes some drawbacks, e.g., a complex fermentation operation, which can be overcome by using soluble inducers such as cellobiose. Here, triple β-glucosidase mutant Neurospora crassa, prevents rapid turnover cellobiose and thus allows disaccharide lignocellulases, was applied profile proteome responses (Avicel). Our...
Abstract High cost of lignocellulases restricts the commercialization biofuel and bio‐product production from lignocellulosic biomass. Constitutively expressed are considered to degrade cellulose release small amount soluble cellodextrins such as cellobiose for further large‐scale lignocellulases; however, underlying mechanism remains be elucidated. Here, a triple β‐glucosidase mutant model fungus Neurospora crassa , which prevents rapid turnover thus allows disaccharide induce...
Nafulsella turpanensis ZLM-10(T) is a slightly halophilic, Gram-negative, rod-shaped, gliding, pale-pink-pigmented bacterium in the family Flammeovirgaceae, and it shows resistance to gentamicin, kanamycin, neomycin, streptomycin. Here, we report genome sequence of N. strain ZLM-10(T), which has 4.8-Mb G+C content 45.67%.
Fungal pathogens have evolved combinations of plant cell-wall-degrading enzymes (PCWDEs) to deconstruct host cell walls (PCWs). An understanding this process is hoped create a basis for improving biomass conversion efficiency into sustainable biofuels and bioproducts. Here, an approach integrating enzyme activity assay, pretreatment, field emission scanning electron microscopy (FESEM), genomic analysis PCWDEs were applied examine digestibility or degradability selected woody herbaceous by...
Objective: To study the intestinal flora specific differences with different lesional stages of metabolic (disorder) associated fatty liver disease (MAFLD), namely simple steatosis and steatohepatitis, so as to provide a new direction for MAFLD-related transplantation targeted therapy. Methods: Mice were fed normal diet, methionine-choline deficient diet (MCD) high-fat high-fructose (HFHF) 12 weeks construct steatohepatitis models. HE Sirius scarlet staining was performed observe...
The extracellular polysaccharide (EPS) matrix embedding microbial cells and soil particles plays an important role in the development of biological crusts (BSCs), which is widely recognized as beneficial to fertility dryland worldwide. This study examined EPS-producing bacterial strains YL24-1 YL24-3 isolated from sandy Mu Us Desert Yulin, Shaanxi province, China. were able efficiently produce EPS; levels EPS determined be 257.22 μg/mL 83.41 cultures grown for 72 h identified Sinorhizobium...