A5012851930- Atrial Fibrillation Management and Outcomes
- Chronic Kidney Disease and Diabetes
- Cardiac Arrhythmias and Treatments
- Dialysis and Renal Disease Management
- Renal Diseases and Glomerulopathies
- Cardiovascular Function and Risk Factors
- Cardiac electrophysiology and arrhythmias
- Medical Research and Treatments
- Cardiac Imaging and Diagnostics
- Traditional Chinese Medicine Studies
- Systemic Lupus Erythematosus Research
- Cardiomyopathy and Myosin Studies
- Lipoproteins and Cardiovascular Health
- Acupuncture Treatment Research Studies
- Heart Failure Treatment and Management
- Artificial Intelligence in Healthcare
- Tuberculosis Research and Epidemiology
- Thyroid Disorders and Treatments
- Machine Learning in Healthcare
- Health Systems, Economic Evaluations, Quality of Life
- Acute Ischemic Stroke Management
- Healthcare Systems and Public Health
- Thyroid Cancer Diagnosis and Treatment
- Lipid metabolism and disorders
- Endometrial and Cervical Cancer Treatments
Capital Medical University
2015-2025
Beijing Anzhen Hospital
2016-2025
China National Health Development Research Center
2022-2025
Beijing Hospital of Traditional Chinese Medicine
2018-2024
Tsinghua University
2024
National Medical Products Administration
2024
Huazhong University of Science and Technology
2024
Nanjing Medical University
2013-2024
Tang Du Hospital
2023
Air Force Medical University
2023
Robust data on the contemporary management of atrial fibrillation (AF) patients in China are limited. Importantly current practice AF has changing dramatically recent years. Data from a large registry study will enable us to evaluate uptake and outcomes with different therapies Chinese population.The Atrial Fibrillation Registry (CAFR) aims enroll 20,000 consecutive 32 tertiary non-tertiary hospitals Beijing, China, follow up these every 6 months until 2020. Key collected includes basic...
This study sought to explore the relationship between plasma galectin-3 (Gal-3) and persistent atrial fibrillation (PsAF), investigate whether Gal-3 predicts clinical outcomes in patients with PsAF undergoing catheter ablation. Fifty consecutive without coexisting structural heart disease first-time ablation 46 healthy controls were included. Blood samples collected on admission for analysis of Gal-3. Pre-ablation laboratory data also recorded. Persistent fibrillations followed after AF...
ABSTRACT Background Atrial fibrillation (AF) and atrial flutter (AFL) represent increasingly significant health burden globally. We aimed to systematically evaluate the status trends of AF/AFL attributable risk factors in China. Methods assessed measured as prevalence, incidence, mortality, disability‐adjusted life years (DALYs), by sex age groups China based on Global Burden Diseases Study (GBD) 2021 project. Results In China, there were 10,775.72 thousand prevalent cases, 916.18 incident...
BACKGROUND Dyslipidemia is the most frequent comorbidity in patients with cardiovascular disease. However, studies examining relationship between blood lipid profiles and AF have produced inconsistent results. MATERIAL AND METHODS A total of 651 were enrolled into 3 groups: Healthy controls (n=64), Paroxysmal (PAF; n=270), Continuous (CAF; n=317). All underwent routine baseline 12-lead electrocardiography (ECG) 24-h dynamic ECG along testing, which included following: complete metabolic...
The role of statins in unruptured intracranial aneurysm (UIA) growth and rupture remains ambiguous. This study sought to determine whether atorvastatin is associated with patients harboring UIA <7 mm.This prospective, multicenter cohort consecutively enrolled concurrent mm ischemic cerebrovascular disease from four hospitals between 2016 2019. Baseline follow-up patient information was recorded. Because the strong anti-inflammatory effect aspirin, using aspirin were excluded. Patients taking...
Abstract Background and Objectives Hyperglycemia is associated with adverse outcomes in patients acute myocardial infarction (AMI) as well heart failure. However, the significance of admission glycemic variability (GV) predicting among diabetes failure (HF) following ST-segment elevation (ASTEMI) remains unclear. This study aims to explore prognostic value GV glycosylated hemoglobin (HbA1c) levels individuals diagnosed type 2 HF ASTEMI. Methods We measured HbA1c upon 484 consecutive GV,...
<b><i>Context:</i></b> Patients with chronic kidney disease (CKD) usually manifest disorder of thyroid hormone; however, the correlation is unknown. <b><i>Objective:</i></b> The study was designed to explore relationships between CKD and dysfunction. <b><i>Design, Setting, Participants:</i></b> A total number 905 non-dialysis participants were collected at Nanjing First Hospital from August 2009 October 2012 according...
Functionally, left His-Purkenje system (HPS) is insulated from the adjacent myocardium and exhibits isolated conduction during sinus rhythm (SR), but in vivo human study rare. Meanwhile, whether also exists idiopathic ventricle tachycardia (ILVT) not clearly defined. The current aimed to delineate activation sequence gross anatomy of HPS SR ILVT.The involved 25 consecutive patients with ILVT. During SR, exhibited antegrade sequence, its surrounding depolarized after an apical base direction....
To evaluate the Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) four-level race equation in assessment of glomerular filtration rate (GFR) Chinese people with chronic kidney disease (CKD), which was published 2011, compared cystatin C-based GFR estimation (CysC GFR) and combination CysC serum creatinine (CysC-Scr GFR).The CKD-EPI estimated (CKD-EPI CysC-Scr GFR. Three equations were body surface area (BSA) standardized (sGFR), measured by (99m) Tc-DTPA renal dynamic imaging...
To evaluate the applicability of Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equation to estimate glomerular filtration rate (GFR) in Chinese patients different stages CKD.The CKD-EPI estimated GFR (eGFR) was compared with body surface area standardized (sGFR), which measured by diethylenetriaminepentaacetic acid renal dynamic imaging method 142 CKD cases.eGFR positively correlated sGFR (r = 0.838, p < 0.001). eGFR 15%, 30%, and 50% accuracy were 31.0%, 57.7%, 76.8%,...
Abstract Aims To distinguish between constrictive pericarditis (CP) and restrictive cardiomyopathy (RCM) using cardiac magnetic resonance feature tracking (CMR‐FT) left ventricle (LV) diastolic time–strain curve patterns myocardial strain. Methods Results A total of 32 CP patients, 27 RCM 25 control subjects were examined by CMR‐FT analysed for global strain, segmental LV in the longitudinal, circumferential, radial directions. Speckle echocardiography (STE) strain imaging was performed some...
Abstract Background An understanding of the risk factors for atrial fibrillation (AF) progression and associated impacts on clinical prognosis are important future management this common arrhythmia. We aimed to investigate rate from paroxysmal (PAF) more sustained subtypes AF (SAF), progression, its impact adverse outcomes. Methods Results Using data Chinese trial Fibrillation Registry study, we included 8290 PAF patients. Half them underwent initial ablation at enrollment. The main outcomes...
Abstract Introduction To assess the long‐term outcome of catheter ablation in patients with hypertrophic cardiomyopathy (HCM), especially apical HCM (ApHCM). Methods and results From 9,249 AF cases, 97 (28 ApHCM 69 non‐ApHCM) were enrolled. Another matched by age, type, duration, left atrial diameter selected as control group. After a mean follow‐up (44.3 ± 29.6) months, success rate after single procedure was 42.9% (P = 0.725), 36.2% non‐ApHCM 0.136) versus 50.5% multiple procedures, both...
Beta-2 microglobulin (B2M) and cystatin C are novel glomerular filtration markers that have a stronger association with adverse outcomes than creatinine. The B2M-based rate (GFR) estimating equation was built in 2016. Several new creatinine equations were developed 2019 China. However, external validation of these remains to be seen.This is prospective cohort study. validated population totaling 830 participants (median age 62 years). These include the (built 2016), three CKD-EPI 2009 2012),...
Abstract This study was to explore the association between thyroid dysfunction and albuminuria. 581 cases with chronic kidney disease (CKD) were included in this study. The clinical characteristics consisted of sex, age, serum creatinine, urinary albumin-to-creatinine ratio (ACR), function recorded. Estimated glomerular filtration rate (eGFR) calculated by CKD-EPI four-level race equation. Prevalence different diseases chi-square test. Levels hormone compared among albuminuria groups...
Vaccines have an essential role in preventing infectious diseases and reducing the burden of disease. The differences vaccine lists prices, National Immunization Program (NIP) development between China United States (US) conjunction with epidemiologic data on were systematically compared. 2019 extracted from Health Commission US Centers for Disease Control Prevention (CDC). list was identified Medical Products Administration Food Drug databases. Vaccine prices obtained via government...
Dividing patients into similar groups plays a significant role in implementing personalized care. Clinicians and researchers have been applying patient grouping techniques disease phenotyping, risk stratification, medicine. However, the current approaches are either based on pure domain knowledge where underlying similarity cannot be precisely quantified, or unsupervised clustering which completely ignore clinical context of measuring similarity. In study, we propose an outcome-driven...
Our previous study demonstrated that the cystatin C-based chronic kidney disease (CKD)-EPI equation and combined by serum creatinine (CKD-EPIscr-cys) had better capability to accurately evaluate glomerular filtration rate in CKD participants. Considering accuracy of estimated (eGFR) remains less ideally, it is essential modify including Chinese eGFR racial factor order improve its performance.Two prospective cohorts were enrolled 2 medical centers. New equations developed 529 participants...
Accurate prediction of ischemic stroke is required for deciding anticoagulation use in patients with atrial fibrillation (AF). Even though only 6% to 8% AF die from stroke, about 90% are indicated anticoagulants according the current management guidelines. Therefore, we aimed develop an accurate and easy-to-use new risk model 1-year thromboembolic events (TEs) Chinese patients.From prospective China Atrial Fibrillation Registry cohort study, identified 6601 who were not treated or ablation...