- Advanced MRI Techniques and Applications
- NMR spectroscopy and applications
- Acoustic Wave Resonator Technologies
- Advanced NMR Techniques and Applications
- Atomic and Subatomic Physics Research
- Stress Responses and Cortisol
- Quantum Dots Synthesis And Properties
- Microwave Engineering and Waveguides
- Digital Radiography and Breast Imaging
- Groundwater flow and contamination studies
- Electrochemical sensors and biosensors
- Medical Imaging Techniques and Applications
- Electron Spin Resonance Studies
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Wastewater Treatment and Nitrogen Removal
- Immune cells in cancer
- Supercapacitor Materials and Fabrication
- Immunotherapy and Immune Responses
- 3D Printing in Biomedical Research
- Photosynthetic Processes and Mechanisms
- Advanced X-ray and CT Imaging
- Cancer, Stress, Anesthesia, and Immune Response
- Microbial Fuel Cells and Bioremediation
- Glycosylation and Glycoproteins Research
- Solid-state spectroscopy and crystallography
Universitätsklinikum Würzburg
2025
Universitätsklinikum Erlangen
2021-2022
Friedrich-Alexander-Universität Erlangen-Nürnberg
2021-2022
Wageningen University & Research
2019-2021
Resonance Research (United States)
2021
Duke University
2018
Abstract Neutrophil extracellular traps (NETs) are structures, composed of nuclear DNA and various proteins released from neutrophils. Evidence is growing that NETs exert manifold functions in infection, immunity cancer. Recently, have been detected colorectal cancer (CRC) tissues, but their association with disease progression putative functional impact on tumourigenesis remained elusive. Using high‐resolution stimulated emission depletion (STED) microscopy, we showed citrullinated histone...
Advanced colorectal carcinoma (CRC) is characterized by a high frequency of primary immune evasion and refractoriness to immunotherapy. Given the importance interferon (IFN)-γ in CRC immunosurveillance, we investigated whether how acquired IFN-γ resistance tumor cells would promote growth, sensitivity could be restored.Spontaneous colitis-associated development was induced mice with specific pathway inhibition intestinal epithelial cells. The influence gene status expression on survival...
Abstract Background Corticotropin-releasing hormone (CRH) is involved in the regulation of immunological and cellular processes. Recently, CRH has been found to be expressed skin cancers, where its expression appears correlate with degree malignancy. Objective This study correlates melanoma metastases patient survival compares intensity that less aggressive cancer entities. Methods Tissue microarrays cores from 94 melanomas 40 melanocytic nevi 51 slides 41 basal cell carcinomas (BCC) 10...
The use of microbial fuel cells (MFCs) for wastewater treatment fits in a circular economy context, as they can produce electricity by the removal organic matter wastewater. Activated carbon (AC) granules are an attractive electrode material bioanodes MFCs, cheap and provide electroactive bacteria with large surface area attachment. characterization biofilm growth on AC granules, however, is challenging due to their high roughness three-dimensional structure. In this research, we show that...
Interactions between plants and the soil's microbial & fungal flora are crucial for health of soil ecosystems food production. Microbe-plant interactions difficult to investigate in situ due their intertwined relationship involving morphology metabolism. Here, we describe an approach overcome this challenge by elucidating metabolic profile Medicago truncatula root nodules using Magnetic Resonance (MR) Microscopy, at highest magnetic field strength (22.3 T) currently available imaging. A...
Abstract Despite aerobic granular sludge wastewater treatment plants operating around the world, our understanding of internal granule structure and its relation to efficiency remains limited. This can be attributed in part drawbacks time-consuming, labor-intensive, invasive microscopy protocols which effectively restrict samples sizes may introduce artefacts. Time-domain nuclear magnetic resonance (NMR) allows non-invasive measurements describe structural features opaque, complex materials...
This work provides a systematic comparison of the signal-to-noise ratio (SNR), spatial resolution, acquisition time and metabolite limits-of-detection for magnetic resonance microscopy spectroscopy at three different field strengths 14.1 T, 17.6 T 22.3 (the highest currently available imaging), utilizing commercially hardware. We find an SNR increase factor 5.9 going from to using 5 mm radiofrequency (saddle birdcage) coils, which results in 24-fold acceleration deviates theoretically...
We make use of the state-of-the-art semiconductor detector Medipix2 in order to obtain high resolution low-dose images samples with dental implants real time. The goal is develop a method direct observation and monitoring interface between surrounding material tissue.
The emerging field of biofabrication capitalizes on nature's ability to create materials with a wide range well-defined physical and electronic properties. Particularly, there is current push utilize programmed, self-organization living cells for material fabrication. However, much research still necessary at the interface synthetic biology engineering make viable technique develop functional devices. Here, authors exploit Escherichia coli contribute fabrication by designing optimizing...
This protocol describes a signal-to-noise ratio (SNR) calibration and sample preparation method for solenoidal microcoils combined with biological samples, designed high-resolution magnetic resonance imaging (MRI), also referred to as MR microscopy (MRM). It may be used at pre-clinical MRI spectrometers, demonstrated on Medicago truncatula root samples. Microcoils increase sensitivity by matching the size of RF resonator interest, thereby enabling higher image resolutions in given data...
This protocol describes a signal-to-noise ratio (SNR) calibration and sample preparation method for solenoidal microcoils combined with biological samples, designed high-resolution magnetic resonance imaging (MRI), also referred to as MR microscopy (MRM). It may be used at pre-clinical MRI spectrometers, demonstrated on Medicago truncatula root samples. Microcoils increase sensitivity by matching the size of RF resonator interest, thereby enabling higher image resolutions in given data...