- Politics and Conflicts in Afghanistan, Pakistan, and Middle East
- South Asian Studies and Conflicts
- Southeast Asian Sociopolitical Studies
- Asian Geopolitics and Ethnography
- International Development and Aid
- Military History and Strategy
- International Relations and Foreign Policy
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Lipid Membrane Structure and Behavior
- Terrorism, Counterterrorism, and Political Violence
- Belt and Road Initiative
- Force Microscopy Techniques and Applications
- Prion Diseases and Protein Misfolding
- China's Ethnic Minorities and Relations
- Mechanical and Optical Resonators
- American Constitutional Law and Politics
- Legal Studies and Policies
- Indian Economic and Social Development
- Global Maritime and Colonial Histories
- Social and Economic Development in India
- Philippine History and Culture
- Eurasian Exchange Networks
- Security, Politics, and Digital Transformation
- Cardiac Fibrosis and Remodeling
- Neurological diseases and metabolism
Institute of Microbial Technology
2018-2025
Council of Scientific and Industrial Research
2018-2025
United Health Services
2022-2024
Indian Institute of Petroleum
2024
All India Institute of Medical Sciences Rishikesh
2024
University of Cincinnati Medical Center
2024
Leeds Arts University
2024
University of Leeds
2024
University of Cincinnati
2023
Institute for Defence Studies and Analyses
2011-2016
Parkinson's disease (PD) is the second most prevalent neurodegenerative disorder. The presence of Lewy bodies, primarily consisting amyloid aggregates protein α-synuclein (α-Syn), a common feature seen in dopaminergic neurons patients. In present study, we screened 2320 FDA-approved drugs and found 3 lead molecules, sulfamerazine, lathosterol, tamoxifen, that reproducibly inhibited α-Syn fibrillation. Dose-response studies showed sulfamerazine lathosterol are relatively more potent than...
The end of the cold war brought tectonic changes in world politics. witnessed its structure, actors as well With changing politics emerged new trends, fresh goals, advanced aspirations, and modernistic expectations. Besides usual theoretical traditions common to International Relations, novel theories, that became impossible ignore. genesis concept ‘soft power’ institutions such G20 is upshot this development. This period also marked amazing emergence developing countries India consolidating...
Idiopathic pulmonary fibrosis (IPF) is marked by the activation of fibroblasts, leading to excessive production and deposition extracellular matrix (ECM) within lung parenchyma. Despite pivotal role ECM overexpression in IPF, potential negative regulators fibroblasts have yet be identified. Semaphorin class 3B (SEMA3B), a secreted protein highly expressed tissues, has established roles axonal guidance tumor suppression. However, SEMA3B pathogenesis IPF remains unexplored. Here, we show downregulation
The mechanical stability of proteins varies with size surrounding anions.
It is not often that Pakistan talked of in terms the diversities it embodies. is, perhaps, its descent into extremism and violence has overshadowed every other characteristic c...
Prion-like self-perpetuating conformational conversion of proteins is involved in both transmissible neurodegenerative diseases mammals and non-Mendelian inheritance yeast. The transmissibility amyloid-like aggregates dependent on the stoichiometry chaperones such as heat shock (Hsps), including disaggregases. To provide mechanistic underpinnings formation persistence prefibrillar amyloid seeds, we investigated role substoichiometric Hsp104 vitro aggregation prion domain (NM-domain)...
Abstract Parkinson’s disease (PD) is the second most common neurodegenerative disease. The presence of lewy bodies, primarily consisting α-synuclein (α-syn) aggregates one features seen in substantia nigra region brain PD patients. remains incurable and only symptomatic relief available. We screened various cell-penetrating peptides reveal that penetratin a potent inhibitor α-syn aggregation in-vitro , significantly improved locomotor coordination mice models in-vivo . peptide inhibits vitro...
Abstract This article is an attempt to understand India's concerns over the Diamer Bhasha dam project within overall ambit of approach towards Pakistan-occupied Kashmir (PoK). It makes a holistic assessment feasibility project, political and technical issues involved in it, long-term strategy Pakistan China region, local reactions, which must inform future policy preferences regarding PoK. The divided into three parts. first part deals with factors that make controversial these are discussed...
The article primarily seeks to understand the relevance of cross-Line Control (LoC) trade and travel in its present shape determine salience overall ambit with regard Kashmir issue for India Pakistan. Simultaneously, it looks at whether cross-LoC initiative is reflective larger issues pending between Pakistan bilateral level. It attempts study nuances related role trade/travel takes a retrospective view see opening up LoC has eased situation. gauges limitations exchange later draws...
Independent India was born beset with territorial complexities, owing to an excruciatingly painful Partition and partly due also previously unresolved boundary issues inherited from the British....
<title>Abstract</title> Human nutrition and health rely on edible oils. Global demand for oils is expanding, necessitating the discovery of new natural oil sources subjected to adequate quality safety evaluation. However, in contrast other agricultural products, India's supply surprisingly dependent imports. The microbial generated by fermentation oleaginous yeast <italic>Rhodotorula mucilaginous </italic>IIPL32 MTCC 25056 using biodiesel plant byproduct crude glycerol as a fermentable...
Introduction: Premature coronary artery disease (CAD) is defined as CAD prior to the age of 55 for men and 65 women, while in young <45 years. In last decade, incidence global premature has increased by 25 %. Case presentation: A 20-year-old female with medical history dyslipidemia, hypertension, type 1 diabetes mellitus family presented emergency room chief complaint chest pain shortness breath. EKG revealed sinus tachycardia poor R-wave progression on anterior precordial leads. Serum...
Introduction: Transcatheter aortic valve replacement (TAVR) is the preferred treatment for stenosis (AS) in patients with high surgical risk. This case report delves into a rare, significant intra-procedural mitral regurgitation (MR) of TAVR. Case Presentation: A 94-year-old female severe AS and STS score 3.9% underwent recent 2D ECHO revealed AS. CT angiogram pre-TAVR exhibited scattered coronary artery calcifications, calcification, calcified atherosclerotic plaque. During procedure, 26mm...
Introduction: Vagal schwannomas are rare, benign masses that usually develop in the cervical region but can arise anywhere along vagus nerve. Patients may be asymptomatic; however, most cases, patients present their third to sixth decades, with neck swelling, hoarseness or cough. Herein, we discuss a case report of 26-year-old male who presented after an abrupt syncopal episode sinus bradycardia and was diagnosed vagal schwannoma. Case Presentation: A past medical history bipolar disorder...
This special section of Contemporary South Asia brings together a curated selection papers presented at the 2023 British Association for Asian Studies (BASAS) Annual Conference, held University Leeds. These explore enduring themes memory politics, state power, and socio-spatial exclusion in Asia, examining how colonial legacies shape contemporary dynamics. Collectively, studies underscore persistence pasts modern India's socio-political landscape illuminate creative strategies resistance...
Youth unrest in higher education institutions (HEIs) India has been an ongoing concern, deeply intertwined with societal, economic, and political dynamics. This review explores the historical roots, causes, manifestations, implications of student unrest, which often arises from issues like governance, socio-economic inequality, discrimination, interference. It delves into recent developments such as digital activism intersectional movements, a focus on resistance against privatization. While...
"Louis D. Hayes. The Islamic State in the Post-Modern World: Political Experience of Pakistan." Asian Affairs, 47(3), pp. 510–511