- Pregnancy and Medication Impact
- Gout, Hyperuricemia, Uric Acid
- Systemic Lupus Erythematosus Research
- Ethics and Legal Issues in Pediatric Healthcare
- Case Reports on Hematomas
- Nicotinic Acetylcholine Receptors Study
- Urticaria and Related Conditions
- Pathogenesis and Treatment of Hiccups
- Gastroesophageal reflux and treatments
- Ethics in medical practice
- Medicinal plant effects and applications
- Patient-Provider Communication in Healthcare
- Pharmaceutical industry and healthcare
- Biomedical Ethics and Regulation
- Inhalation and Respiratory Drug Delivery
- Reproductive System and Pregnancy
- Bacillus and Francisella bacterial research
- Patient Dignity and Privacy
Memorial University of Newfoundland
2019
University of Alabama at Birmingham
2017-2019
Center for Rheumatology
2019
Office of Infectious Diseases
2007
Background Treatment decision-making regarding immunosuppressive therapy is challenging for individuals with lupus. We assessed the effectiveness of a decision aid in lupus nephritis. Methods and findings In United States multicenter, open-label, randomized controlled trial (RCT), adult women nephritis, mostly from racial/ethnic minority backgrounds low socioeconomic status (SES), seen in- or outpatient settings, were to an individualized, culturally tailored, computerized versus American...
Bacillus anthracis edema toxin (ET), composed of protective antigen and an adenylate cyclase factor (EF), elicits in host tissues, but the target cells events leading from EF-mediated cyclic-AMP production to are unknown. We evaluated direct effect ET on several cell types vitro tested possibility that mediators vascular leakage, such as histamine, contribute rabbits given intradermal ET. increased transendothelial electrical resistance endothelial monolayers, a response is mechanistically...
Research is limited on how nurses in community settings manage ethical conflicts. To address this gap, we conducted a study to uncover the process of behaviors enacted by when experiencing Guided Glaserian grounded theory, developed theoretical model (Moral Compassing) that enables us explain 24 managed challenging situations. We discovered main concern with which wrestle moral uncertainty (“Should I be addressing what think problem?”). Moral Compassing comprises processes resolve providing...
Systemic Lupus erythematosus (SLE), also commonly referred to as lupus, is a rare, but sometimes, fatal disease, that primarily affects young women. nephritis, common manifestation of more and devastating in patients minority race/ethnicity. Patients have negative views immunosuppressive drugs for lupus nephritis due concern about side effects under-appreciation its benefit. We designed study assess the effectiveness individualized, computerized patient decision-aid compared standard...
Objective The aim of this study was to conduct a 9-month pilot Internet randomized controlled trial (RCT) cherry extract and diet modification in gout assess the feasibility an obtain effect estimates. Methods After providing online informed consent response advertisements social media or clinic flyers, 84 people with physician-confirmed were either 3,600 mg/d (n = 41) dietitian-assisted for 43). All outcomes collected via phone calls. primary objective study, secondary objectives estimates...
Objective The aim of this study was to report patient-centered outcomes and finalization key procedures from a 9-month pilot internet randomized controlled trial cherry extract versus diet modification. Methods We 84 people with physician-confirmed gout in an (n = 41) or dietitian-assisted modification for 43). All were collected via phone calls. finalized procedures. assessed acceptability feasibility the intervention satisfaction website. Results Study participant high. perceived as easy,...
<h3>Background</h3> Medication decision-making is challenging in lupus. No validated, effective decision-aids are available to assist patients with medication decision-making. <h3>Objectives</h3> Our objective was assess the effectiveness of an individualized, culturally-tailored, computerized decision-aid for immunosuppressive medications lupus nephritis. <h3>Methods</h3> In a multicenter, randomized controlled trial, diverse adult women nephritis, largely racial/ethnic minorities low...