OBJECTIVE. We aimed to detect biliary atresia (BA) in early infancy prevent additional liver damage because of the delay referral and surgical treatment investigate incidence rate BA Taiwan. METHODS. A pilot study screen stool color infants for diagnosis was undertaken from March 2002 December 2003. had designed an “infant card” with 7 numbers different pictures attached it child health booklet. Parents were then asked observe their infant's by using this card. The medical staff would check...

Abstract Background SOX genes play an important role in a number of developmental processes. Potential roles SOXs have been demonstrated various neoplastic tissues as tumor suppressors or promoters depending on status and types. The aim this study was to investigate the involvement progression prognosis human prostate cancer (PCa). Methods gene expression changes PCa compared with non-cancerous detected using microarray, confirmed by real-time quantitative reverse transcriptase-polymerase...

The present study aimed to investigate faecal calprotectin as a diagnostic marker differentiate between patients with inflammatory bowel disease (IBD) and those irritable syndrome (IBS). A total of 20 healthy control subjects, 26 IBS 58 IBD, including 22 ulcerative colitis (UC) 36 Crohn's (CD), were recruited for the study. Calprotectin was analysed in stool samples, C-reactive protein (CRP) erythrocyte sedimentation rate (ESR) assessed blood samples. CRP levels, ESR observed be...

Accumulating evidence suggests that there is a link between the host microbiome and pancreatic carcinogenesis, Porphyromonas gingivalis (P. gingivalis) increases risk of developing cancer. The aim current study was to clarify role P. in pathogenesis cancer potential immune modulatory effects probiotics. six-week-old LSL-K-rasG12D; Pdx-1-cre (KC) mice smeared on gums, causing intraepithelial neoplasia (PanIN) after four weeks be similar extent lesions untreated KC at 24 weeks. oral...

To investigate the mechanism by which peroxiredoxin III (PRDX3) is altered in human prostate cancer (PCa), we used microRNA (miRNA) target prediction program and miRNA microarray to predict identify miR‐23b as a candidate that targets PRDX3. We showed suppresses PRDX3 protein expression DU145 cells under normal hypoxic conditions. Additionally, clinical significance of PCa patients was also confirmed. In conclusion, our data suggest effects progression may be caused regulation function...

SUMMARY: Aim: Acute pyelonephritis is a common infectious disease in children and can result permanent renal damage. Interleukin (IL)‐1β an important inflammatory mediator that appears early during bacterial infection. This prospective study examined urine IL‐1β levels with acute documented by 99m Tc‐dimercaptosuccinic acid (DMSA) scan, also evaluated whether this cytokine correlated scarring. Methods: A total of 75 aged 1–121 months diagnosis first‐time febrile urinary tract infection (UTI)...

The aim of this article was to assess the usefulness procalcitonin (PCT) as a marker for predicting dilating (grades III-V) vesicoureteral reflux (VUR) in young children with first febrile urinary tract infection.Children ≤2 years age infection were prospectively evaluated. Serum samples tested PCT at time admission tertiary hospital. All underwent renal ultrasonography (US), Tc-dimercaptosuccinic acid scan, and voiding cystourethrography. diagnostic characteristics test acute pyelonephritis...

This study aimed to examine the ability of acute (99m)Tc DMSA scan for predicting dilating (grades III-V) vesicoureteral reflux (VUR) after a first febrile urinary tract infection in children aged 2 years or younger.All underwent ultrasonography (US), scan, and voiding cystourethrography. Sensitivity, specificity, positive negative predictive values, likelihood ratios, receiver operating characteristic curves were performed assess diagnostic accuracy VUR. Follow-up was at least 6 months...

Rotavirus and norovirus are the most common known causes of viral gastroenteritis in children. This study examined association between serum interleukin 6 (IL-6) 8 (IL-8) levels disease severity acute phase rotavirus children, it also explored role fecal cytokine children with bacterial gastroenteritis.This prospective enrolled patients aged 4 months to 14 years admitted a tertiary care center. Peripheral blood samples were collected for IL-6 IL-8 assays within first 3 days diarrhea. Stool...

Background: Interleukin (IL)-8 acts as a potent neutrophils chemoattractant responsible for the migration of into infected renal tissue to protect against invading pathogens. The aim this study was assess role IL-8 on acute-phase pyelonephritis and later scarring in children. Patients Methods: A total 124 children with first-time febrile urinary tract infection (UTI) were studied. diagnosis acute confirmed by 99mTc-dimercaptosuccinic acid (DMSA) scan. Serum urine samples obtained from UTI 20...

No AccessJournal of UrologyPediatric Urology1 Nov 2011The Role Procalcitonin for Acute Pyelonephritis and Subsequent Renal Scarring in Infants Young Children Ji-Nan Sheu, Hung-Ming Chang, Shan-Ming Chen, Tung-Wei Hung, Ko-Huang Lue SheuJi-Nan Sheu More articles by this author , ChangHung-Ming Chang ChenShan-Ming Chen HungTung-Wei Hung LueKo-Huang View All Author Informationhttps://doi.org/10.1016/j.juro.2011.07.025AboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack...

Acute pyelonephritis is a common infectious disease in children and can result permanent renal damage. Interleukin-6 (IL-6) an important mediator of inflammation response to bacterial infection. This study investigated the potential relationship between acute-phase IL-6 subsequent scarring with first time febrile acute pyelonephritis.In total, 79 (age range 1-120 months) urinary tract infection (UTI) were included. The diagnosis was confirmed by (99m)Tc-dimercaptosuccinic acid (DMSA) scan....

Objective Bronchopulmonary dysplasia (BPD) is a complex chronic lung disease that primarily affects premature or critically ill infants. This pilot study investigated early changes in gut microbiota composition BPD patients and explored the potential risk factors associated with these changes. Study Design Preterm infants admitted to our neonatal intensive care unit gestational age of 26 32 weeks were prospectively surveyed eligible for stool collection on days 7 28 postnatal between...

The association between air pollution, allergic rhinitis (AR), and obesity has not been studied. From 2007 to 2011, 52 obese 152 non-obese children (7-17 years old) with AR were recruited. Pediatric-Rhinoconjunctivitis-Quality-of-Life Questionnaire (PRQLQ) nasal peak expiratory flow (NPEF) tested. Association the scores rates of two tests mean pollutant concentrations within 7 days before compared. When exposed higher CO, PM10, PM2.5, worse discomfort 39.4%, 44.4% 39.3% in children; 18.0%,...

Objective To investigate whether Sjogren's syndrome would have an influence on the development of Parkinson's disease. Methods A population-based case-control study was conducted. Participants consisted 7716 subjects with newly diagnosed disease and a population 75129 matched control between 2000 2010. We measured risk in association by using adjusted odds ratios. Results total 143 (1.9%) 893 (1.2%) suffered from (p < 0.001). The crude ratio for among 1.56 (95% CI 1.30–1.86; p 0.01). After...

Minimally invasive surfactant therapy (MIST) is a new mode of administration without intubation to spontaneously breathing preterm infants with respiratory distress syndrome (RDS). The aims this study were assess the feasibility, efficacy and safety using MIST give for very low birth weight (VLBW) RDS.In total, 53 VLBW who born before 32 gestational weeks spontaneous breathing, distress, requiring divided into two groups. in group A (n = 29) intubated received replacement via endotracheal...

Objectives Urinary tract infection (UTI) is a common bacterial in children that can result permanent renal damage. This study prospectively assessed the diagnostic performance of procalcitonin (PCT) for predicting acute pyelonephritis (APN) among with febrile UTI presenting to paediatric emergency department (ED). Methods Children aged ≤10 years admitted hospital from ED were studied. Blood PCT, C reactive protein (CRP) and white blood cell (WBC) count measured ED. Sensitivity, specificity,...

Data on urinary tract infection (UTI) in infants ≤2 months of age are limited. We examined clinical characteristics, antimicrobial resistance, imaging findings and outcomes children 2-24 hospitalized with the first febrile UTI.Children ≤24 their first-diagnosed UTI were prospectively studied. Renal ultrasonography, Tc-dimercaptosuccinic acid scanning voiding cystourethrography performed all children.Of 388 analyzed (255 boys 133 girls), 61 patients age, representing 15.7% whole population,...

Since 1998 in Taiwan, enterovirus (EV) 71 epidemics have caused encephalomyelitis and placed a significant burden on parents physicians. In this study, we present clinical manifestations, magnetic resonance (MR) imaging findings, neurological sequelae epidemic EV-infected patients with encephalomyelitis. Of the 46 patients, 14 presented sequelae; of them, 3 suffered from complications mental regression. Predictors unfavorable were myoclonic jerks (> 4 times/night) pleocytosis (167/μL)...