A5109411063- Insect Resistance and Genetics
- Entomopathogenic Microorganisms in Pest Control
- Insect Pest Control Strategies
- Advanced Optimization Algorithms Research
- Matrix Theory and Algorithms
- Insect-Plant Interactions and Control
- Insect and Arachnid Ecology and Behavior
- Adipokines, Inflammation, and Metabolic Diseases
- Adipose Tissue and Metabolism
- Natural product bioactivities and synthesis
- Radiomics and Machine Learning in Medical Imaging
- MRI in cancer diagnosis
- Mycorrhizal Fungi and Plant Interactions
- Insect and Pesticide Research
- Pancreatitis Pathology and Treatment
- Nematode management and characterization studies
- Phytochemical Studies and Bioactivities
- Plant-Microbe Interactions and Immunity
- Alkaloids: synthesis and pharmacology
- Genetic Mapping and Diversity in Plants and Animals
- Cardiovascular Disease and Adiposity
- Astro and Planetary Science
- Planetary Science and Exploration
- Plant Toxicity and Pharmacological Properties
- Lipid metabolism and biosynthesis
East China Normal University
2021-2025
Shandong Provincial Hospital
2023-2024
Fudan University
2018-2024
Shandong Academy of Agricultural Sciences
2020-2024
Institute of Plant Protection
2020-2024
Shandong First Medical University
2023-2024
Shaoguan University
2024
Macau University of Science and Technology
2023-2024
Capital Normal University
2020-2024
Chengdu University of Traditional Chinese Medicine
2021-2023
Endophytic mycobiomes are an integral part of crops in agricultural systems. Fertilization is a conventional practice to improve and may alter the soil plant In agroecosystems, Nature Based Solutions (NBS) key strategies for suitability. Investigating under N flux can provide fundamental data constructive NBS strategies. this study, effects nitrogen (N) fertilizer treatments on fungal compositions soil-maize systems were systematically investigated field experiments at six rates (F0, F72,...
Abstract Thermogenic fat, including brown and beige dissipates heat via thermogenesis enhances energy expenditure. Thus, its activation represents a therapeutic strategy to combat obesity. Here, we demonstrate that levels of F-box WD repeat domain-containing 7 (FBXW7), an E3 ubiquitin protein ligase, negatively correlate with thermogenic fat functionality. FBXW7 overexpression in suppresses expenditure thermogenesis, thus aggravates obesity metabolic dysfunctions mice. Conversely, depletion...
In recent decades, the prevalence of obesity has been rising. One major characteristics is fat accumulation, including hyperplasia (increase in number) and hypertrophy size). After histological staining, it critical to accurately measure number size adipocytes for assessing severity a timely fashion. Manual measurement accurate but time-consuming. Although commercially available adipocyte counting tools, AdipoCount, Image-Pro Plus, ImageJ were helpful, limitations still exist accuracy time...
Overexpression of various pro-inflammatory factors in microglial cells tends to induce neurodegenerative diseases, for which there is no effective therapy available. Aureonitol (1) and seven analogues, including six previously undescribed [elatumenol A-F (2-4, 6-8, respectively)], along with two new orsellinic acid esters [elatumone A B (9 10)], were isolated from Chaetomium elatum. The structures the compounds established through comprehensive analysis spectroscopic data, high-resolution...
Dai-Huang-Fu-Zi-Tang (DHFZT) is a famous traditional Chinese prescription with intestinal obstruction, acute pancreatitis and cholecystalgia for thousands of years. Our previous work found that DHFZT could act against pulmonary pathological injury in rats severe (SAP). But the underlying mechanism has not been fully elucidated. The aim present study was to investigate whether relieve by regulating aquaporins after SAP induced sodium taurocholate rats. Forty SD were used dose dependant...
Obesity, a metabolic disease caused by multiple factors, has become global health problem.In addition to nutrient intake and sedentary lifestyle, environmental pollutants exposure been shown be involved in obesity epidemics.Antibiotics, new type of pollutant, have widely used animal husbandry, aquaculture microorganism.However, the effects antibiotics on fat metabolism diseases are largely unknown.Methods: We screened major types examine their differentiation capacity thermogenic...
Peroxisome proliferator-activated receptor γ (PPARγ) is a master regulator of adipocyte differentiation, glucolipid metabolism, and inflammation. Thiazolidinediones are PPARγ full agonists with potent insulin-sensitizing effects, whereas their oral usage restricted because unwanted side including obesity cardiovascular risks. Here, via virtual screening, microscale thermophoresis analysis, molecular confirmation, we demonstrate that diosmin, natural compound wide long-term clinical use,...
Maize is one of the major crops cultivated in northern Shandong Province and contributes significantly to China's maize production, nitrogen (N) application soil can have a marked impact on yield microbial productivity. The current environmental challenge, which needs urgently be addressed, effectively utilize fertilizer improve crop production without causing stress sustainable agroecosystems. Soil fungi plant health performance through improved nutrient uptake reducing levels. How N...
FBXO32 has recently been identified as a TGF-β/Smad signaling pathway target gene, involved in regulating cell survival and may be transcriptionally silenced by epigenetic mechanisms some kind of carcinomas. The present study was to investigate the role promoter methylation status gastric cardia adenocarcinoma (GCA), determine prognostic significance GCA. Bisulfite Conversion-Specific Methylation-Specific PCR, real-time RT-PCR immunohistochemical staining methods were used detect expression...
The improvement of crop resistance to insect using endophytic fungi is an environmentally friendly and sustainable strategy for agricultural pest control. Clarifying the efficacy mechanism in improving offers opportunity biological In this study, changes transcriptome defense compounds wheat inoculated with fungal strains (i.e., YC BB) were evaluated, Rhopalosiphum padi was studied. results showed that numbers upregulated differentially-expressed genes (DEGs) plants BB higher than those...
Abstract Determining asteroid properties provides valuable physical insights but inverting them from photometric lightcurves remains computationally intensive. This paper presents a new approach that combines simplified Cellinoid shape model with the Parallel Differential Evolution (PDE) algorithm to accelerate inversion. The PDE is more efficient than algorithm, achieving an extraordinary speedup of 37.983 64 workers on multicore CPUs. accurately derives period and pole values simulated...
Abstract Objective To determine the performance of intravoxel incoherent motion (IVIM) parameters and extracellular volume fraction (ECV) in distinguishing between different subtypes lung cancer predicting lymph node metastasis (LNM) status patients with non-small-cell (NSCLC). Methods One hundred sixteen were prospectively recruited. IVIM, native, postcontrast T1 mapping examinations performed, values measured to calculate ECV. The differences IVIM ECV compared NSCLC small-cell (SCLC),...
In an effort to develop novel molecules with suitable insecticidal activities, 23,24-alkene-avermectin B2a derivatives have been synthesized via a one-pot multistep reaction using avermectin B2a, byproduct of fermentation, as starting material. All products and intermediates were characterized by 1H NMR, 13C high-resolution mass spectrometry. Bioassay results showed that the LC50 values compounds 4 9 against Meloidogyne incognita 0.63 0.50 mg/L, respectively, similar (0.46 mg/L)....
Amestolkins A (1) and B (2), two previously undescribed phthalides sharing the same planar structure of (1, 5-dihydroxyhexyl)-7-hydroxyisobenzofuran-1(3H)-one were isolated from Talaromyces amestolkiae. Their absolute configurations elucidated by comprehensive analyses spectroscopic evidences in high-resolution electrospray mass spectra (HRESIMS) nuclear magnetic resonance (NMR) combined with electronic circular dichroism (ECD) NMR calculations. 1 2 showed anti-neuroinflammatory activity...