Abstract Objective: To explore the safety of ultrasound and microbubbles for enhancing chemotherapeutic sensitivity malignant tumors in digestive system a clinical trial, as well its efficacy. Methods: From October 2014 to June 2016, twelve patients volunteered participate this study. Eleven had hepatic metastases from system, one patient pancreatic carcinoma. According mechanical index (MI) field, were classified into four groups with MIs 0.4, 0.6, 0.8 1.0. Within half an hour after...

Objective: To evaluate the effectiveness and feasibility of Managing Cancer Living Meaningfully (CALM), which is used to reduce chemotherapy-related cognitive impairment (CRCI), relieve psychological distress, improve quality life (QOL) in Chinese breast cancer survivors (BCs). Methods: Seventy-four BCs were enrolled this study. All patients randomly assigned either CALM group or care as usual (CAU) group. evaluated by Functional Assessment Therapy-Cognitive Function (FACT-Cog), Distress...

Lung cancer is the most common and cause of cancer-related mortality worldwide, increasing evidence indicated that there was a significant correlation between tumors long non-coding RNAs (lncRNAs), as well tumor immune infiltration, but their role in early lung adenocarcinoma (LUAD) are still unclear.Gene expression data corresponding clinical early-stage LUAD patients were downloaded from GEO TCGA databases. 24 kinds tumor-infiltrating cells analyzed by quantity analysis univariate cox...

BACKGROUND:Existing research evidence indicates that breast cancer patients have different degrees of cognitive dysfunction after chemotherapy, and polymorphisms in 3 genes (catechol-O-methyltransferase, COMT; apolipoprotein E, APOE; brain-derived neurotrophic factor, BDNF) been associated with impairment. However, the role these gene modulating impairment survivors varying hormonal receptor expression is not clear at present.To explore effects genetic BDNF, APOE, COMT on regulation...

To investigate the relationship between depression and self-reported prospective memory (SPM) problems in breast cancer survivors who have received chemotherapy.Sixty-three patients were administered with self-rating scale (SDS) questionnaire as part of extensive neuropsychological assessments before after chemotherapy. The performance SDS SPM compared, level significance set at P < .05.Compared group chemotherapy, there is a significant difference on score (t = 6.069, .000) Further, also...

Background: The number of patients with breast cancer is increasing worldwide, resulting in a growing chemotherapy-related cognitive impairment (CRCI), which seriously affects their quality life. CRCI associated inflammatory factors and systemic markers such as pan-immune-inflammation value (PIV) monocyte-to-lymphocyte ratio (MLR), can reflect the level inflammation body. While Managing Cancer Living Meaningfully (CALM) intervention has been demonstrated to alleviate cancer, specific...

Transarterial chemoembolization (TACE) is recommended as the first-line treatment in intermediate-stage patients with hepatocellular carcinoma (HCC) or a palliative modality advanced patients. However, tumor control usually requires multiple TACE interventions due to presence of residual and recurrent lesions. Elastography can provide information about stiffness (TS) predict recurrence. In this study, we aimed analyze effects on HCC using ultrasound elastography (US-E). We investigated...

Aim. Through investigation and analysis of the course management 314 patients with benign prostatic hyperplasia (BPH) during COVID-19 pandemic, we expected to offer effective recommendations for BPH against background pandemic. Methods. We implemented telephone follow-ups who were diagnosed at Urology Clinic Xiangya Hospital Central South University before January 24, 2020, admitted hospital reexamination after epidemic was controlled in China, conducted research their disease Results. In...

The aim of this study was to investigate the patterns changes in free portal pressure (FPP) cynomolgus monkeys with different levels liver fibrosis and lay a theoretical foundation for FPP patients fibrosis. Liver models were successfully established 15 20 using carbon tetrachloride, among which 10 developed severe (S4; i.e., early cirrhosis). A randomized block design used that complete values rates change at stages analyzed. normal value 25.56 ± 2.33 mmHg; S1 36.05 2.91 mmHg, an increase...

Abstract Background To evaluate different stages of liver fibrosis in cynomolgus monkeys by comparing magnetic resonance-perfusion weighted imaging (MR-PWI) quantitative and semi-quantitative parameters, confirm the best detection indicators for diagnosis fibrosis. Methods A model (S0–S4) was established monkeys. The changes MR-PWI parameters with progression were investigated. Results gradually decreased Hepatic arterial perfusion index (HPI) found to increase significant differences HPI...

Objective: To investigate the changing rules with (1)H magnetic resonance spectroscopy ((1)H-MRS) in order to provide human research theoretical basis varying degrees of liver fibrosis cynomolgus monkeys. Methods: Liver model twenty-two monkey was successfully established carbon tetrachloride (CCl(4)). Among them, fifteen developed early-stage cirrhosis (S4 stage). A comparative study conducted 15 monkeys that had fully fibrosis. The for were analyzed (1)H-MRS. Supplementary methods:...

Objective To explore the effects of continuous nursing on quality life and disease control in children with bronchial asthma. Methods 77 participants were randomly divided into intervention group (n=39) (n=38). Based conventional mode, received additional after discharging from hospital. The related knowledge their parents, children′s asthma level evaluated according to continuing assessment scale (CTM), childhood test (C.ACT) pediatric questionnaire (PAQLQ) before six months...

Objective To evaluate the early intervention efforts of recombinant human granulocyte macrophage colony-stimulating factor (rhGM-CSF) against nasopharyngeal cancer with radiation-induced oral mucositis.Methods A total 75 patients were randomly assigned to 3 groups:the prevention group (n =25) used rhGM-CSF when radiation started one day,the treatment and control mucositis occurred.Criteria CTC was duration degree pain.Results The had a longer comparing (15.2±3.2),(12.1±2.7),(12.0±2.6) d (t...

Objective To explore the effect of health education pathway on hospitalized children with unintentional injury and their caregivers. Methods From January to December 2015, a total 100 injuries caregivers admitted ICU in class Ⅲ grade A hospital were selected as research objects. They divided into observation group control according random number table, 50 cases each group. Patients received routine education, while patients given based The knowledge, hospitalization expenses, days,...