- Acupuncture Treatment Research Studies
- Migraine and Headache Studies
- Pain Mechanisms and Treatments
- Healthcare and Venom Research
- Olfactory and Sensory Function Studies
- Psychosomatic Disorders and Their Treatments
- Osteoarthritis Treatment and Mechanisms
- Dysphagia Assessment and Management
- Voice and Speech Disorders
- Laser Applications in Dentistry and Medicine
- Dermatology and Skin Diseases
- Myofascial pain diagnosis and treatment
- Complementary and Alternative Medicine Studies
- Restless Legs Syndrome Research
- Hearing, Cochlea, Tinnitus, Genetics
- RNA and protein synthesis mechanisms
- Pregnancy and preeclampsia studies
- Vagus Nerve Stimulation Research
- Cancer-related molecular mechanisms research
- Allergic Rhinitis and Sensitization
- Traditional Chinese Medicine Studies
- Birth, Development, and Health
- Cytokine Signaling Pathways and Interactions
- Psoriasis: Treatment and Pathogenesis
- Trigeminal Neuralgia and Treatments
Capital Medical University
2015-2024
Beijing Hospital of Traditional Chinese Medicine
2015-2024
Beijing Tongren Hospital
2018
Beijing City University
2017
Beijing University of Chinese Medicine
2017
Obesity is a common metabolic syndrome that causes significant burden on individuals and society. Conventional therapies include lifestyle interventions, bariatric surgery, pharmacological therapies, which are not effective have high risk of adverse events. Acupuncture an alternative for obesity, it modulates the hypothalamus, sympathetic activity parasympathetic activity, obesity-related hormones (leptin, ghrelin, insulin, CCK), brain-gut axis, inflammatory status, adipose tissue browning,...
Acupuncture has a therapeutic effect similar to that of prophylactic drugs and can be considered treatment option for migraineurs. However, the mechanism acupuncture treatment's on migraine is uncertain. An approach based anti-inflammatory effects an important strategy because non-steroidal (NSAIDs) are usually used during attacks. Meningeal inflammation thought responsible activation trigeminovascular system. Our previous study found electroacupuncture (EA) decreased neurogenic mediator...
Background While electroacupuncture (EA) pretreatment has been found to ameliorate migraine-like symptoms, the underlying mechanisms remain poorly understood. Emerging evidence suggests that brainstem descending pain modulatory system, comprising periaqueductal grey (PAG), raphe magnus nucleus (RMg), and trigeminal caudalis (TNC), may be involved in migraine pathophysiology. We hypothesised EA would symptoms via modulation of this system. Methods used a conscious rat model induced by...
Acupuncture has been recommended as an alternative therapy for migraine. Emerging evidence suggests that the 5-HT7 receptor (5-HT7R) plays a significant facilitatory role in descending modulation migraine pathophysiology, and activation of 5-HT7R pathway is involved central sensitisation.To investigate ability electroacupuncture (EA) to ameliorate sensitisation via pain pathways using rat model induced by repetitive dural electrical stimulation (DES).64 male Sprague-Dawley rats were randomly...
Background Acupuncture has been used for the treatment of chronic migraine, but high-quality evidence is scarce. We aimed to evaluate acupuncture's efficacy and safety compared topiramate migraine. Methods This double-dummy randomized controlled trial included participants aged 18–65 years diagnosed with They were randomly assigned (1:1) receive acupuncture (three sessions/week) plus placebo (acupuncture group) or (50–100 mg/day) sham (topiramate over 12 weeks, primary outcome being mean...
Most migraine patients suffer from cutaneous allodynia; however, the underlying mechanisms are unclear. Calcitonin gene-related peptide (CGRP) plays an important role in pathophysiology of migraine, and it is therefore, a potential therapeutic target for treating pain. In present study, rat model conscious induced by repeated electrical stimulation superior sagittal sinus, was established treated with electroacupuncture at Fengchi (GB20) (depth 2-3 mm, frequency 2/15 Hz, intensity 0.5-1.0...
Purpose: Macrophage polarization contributes to the mechanisms of treating knee osteoarthritis (KOA). In previous studies, fire needling acupuncture has been shown affect KOA favorably. However, mechanism on macrophage is not well-defined. Thus, this study was conducted determine that exerts a therapeutic role in by modulating polarization. Methods: Thirty mice were allocated at random into three groups ten. The labeled as "control", "model", and "fire acupuncture". Each group consisted ten...
Introduction Approximately 1.4%–2.2% of the global population suffers from chronic migraine. Acupuncture may serve as an alternative management for migraine, where pharmacological prophylaxis is not suitable. However, effects acupuncture migraine have been confirmed. This study designed a single-blinded, double-dummy randomised controlled trial to evaluate efficacy and safety compared with topiramate in patients Methods analysis A total 60 participants will be randomly assigned two different...
Background . While electroacupuncture (EA) pretreatment in migraine has been found to attenuate pain and frequencies of attacks, the underlying mechanism its antinociceptive effect remains poorly understood. Emerging evidence suggests that serotonin system may be involved pathophysiology. Method Forty male Sprague‐Dawley rats were randomly assigned Control, Model, EA, sham acupuncture (SA) groups. HomeCageScan was used measure effects on spontaneous nociceptive behaviors. Radioimmunoassay...
Psoriasis is a common autoimmune disease. Acupuncture-related techniques have been widely used to treat psoriasis since its ability engage neuronal function, the immune system, and other systems well documented. This study aimed investigate compare effects of three acupuncture-related in psoriasis-like skin inflammatory responses explore possible involved mechanisms. Imiquimod (IMQ)-induced mice were treated with acupuncture needling, electroacupuncture, or fire acupuncture. Methotrexate...
Electroacupuncture (EA) is widely used in clinical practice to relieve migraine pain. 5-HT 7 receptor (5-HT R) has been reported play an excitatory role neuronal systems and regulate hyperalgesic pain neurogenic inflammation. R could influence phosphorylation of protein kinase A (PKA)- or extracellular signal-regulated 1 / 2 (ERK )-mediated signaling pathways, which mediate sensitization nociceptive neurons via interacting with cyclic adenosine monophosphate (cAMP). In this study, we...
Migraine onset is associated with the abnormal release of vasoactive neurotransmitters from perivascular nerves, and these are involved in pathophysiology migraine. Hyperalgesia a key feature migraine, accumulating evidence indicates that electroacupuncture (EA) at single acupuncture point (Fengchi [GB20]) effective ameliorating hyperalgesia. In clinical practice, multiple points widely used, especially GB20 Yanglingquan (GB34). However, role played by antihyperalgesic effect or remains...
The aim of this study was to evaluate the efficacy acupuncture, an alternative medicine therapy, as a preventive treatment for menstruation-related migraine (MRM). This prospective, multicenter, double-dummy, participant-blinded, randomized controlled clinical trial conducted in China between 1 April 2013, and 30 2014. participants were enrolled from four centers into either acupuncture group, which received 24 sessions at traditional acupoints plus placebo, or medication sham naproxen....
Abstract Background Temporomandibular disorders (TMD) are the leading cause of pain and disability among frequently occurring facial second musculoskeletal conditions. Aim We examined whether acupuncture could alleviate intensity in patients with TMD. Design methods Sixty participants TMD were randomly assigned (ratio 1:1) to receive three or sham sessions weekly for 4 weeks. The primary outcome was change mean from baseline week 4. Secondary exploratory outcomes included proportion ≥30%...
This rat experiment aims to demonstrate the efficacy of electrical acupuncture in preventing migraine attacks by stimulating acupoint GB20.Migraine, which takes 2ed at level four causes GBD's disease hierarchy, becomes a public health issue. It is important for physicians supplement their knowledge its treatment and consider alternative methods therapy, such as acupuncture. However, neurobiological pathophysiological mechanisms this prophylactic effect were unclear. The trigeminocervical...
To observe the clinical therapeutic effect on post-stroke dysphagia treated with He's santong (triple promotion) acupuncture therapy through surface electromyography (sEMG).A total of 60 patients were divided into a routine treatment group and group, using blocked randomization, 30 cases in each one. In secondary prevention swallowing rehabilitation training adopted. base as weitong (mild promotion, at bilateral Fengchi [GB20], Fengfu [GV16], Yifeng [TE17], Lianquan [CV23], Jia-lianquan...
Dysphagia is a common complication of stroke, affecting up to 78% stroke patients. The existence dysphagia after has been associated with an increased risk for pulmonary complications and even mortality. Previous studies have shown that acupuncture could be potential therapeutic method treatment stroke. A prospective randomized controlled pilot trial designed evaluate the effect He's Santong needling on stroke.Sixty eligible participants will recruited randomly assigned into group (He's...
Knee osteoarthritis (KOA) is regarded as one of the leading musculoskeletal diseases. Although efficacy under exploration, fire needling therapy considered an effective alternative for KOA. This trial aims to investigate effectiveness different frequencies in attenuating pain and promoting function KOA patients.This a study protocol pilot, three-arm, single-center, randomized controlled trial. A total 90 participants with will be recruited randomly assigned high-frequency group (3 sessions...