Jianning Guo

ORCID: 0000-0003-0926-0119
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About
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Research Areas
  • Dermatology and Skin Diseases
  • Psoriasis: Treatment and Pathogenesis
  • Allergic Rhinitis and Sensitization
  • Tryptophan and brain disorders
  • Immune Response and Inflammation
  • Immune cells in cancer
  • Obsessive-Compulsive Spectrum Disorders
  • Chemokine receptors and signaling
  • Phytochemistry and Bioactive Compounds
  • Immune Cell Function and Interaction
  • Traditional Chinese Medicine Studies
  • Plant-based Medicinal Research
  • Asthma and respiratory diseases
  • Chronic Obstructive Pulmonary Disease (COPD) Research
  • Neonatal Respiratory Health Research
  • Traditional Chinese Medicine Analysis
  • Child and Adolescent Health
  • Complementary and Alternative Medicine Studies
  • Acupuncture Treatment Research Studies
  • Respiratory Support and Mechanisms
  • Pediatric health and respiratory diseases
  • Bipolar Disorder and Treatment
  • Circadian rhythm and melatonin
  • Impact of Light on Environment and Health
  • Healthcare and Venom Research

Beijing University of Chinese Medicine
2019-2024

Beijing Hospital of Traditional Chinese Medicine
2019-2024

Capital Medical University
2019-2024

China-Japan Friendship Hospital
2023-2024

Chinese Academy of Medical Sciences & Peking Union Medical College
2024

Beijing Hospital
2020

Abstract Psoriasis is a common, chronic multifactorial inflammatory skin disease with both genetic and environmental components. A number of studies have suggested that psoriasis episodes are often preceded by stressful life events. Nevertheless, the underline mechanisms stress in remain unexplored. To address this question, we established an emotional mouse model induced empty bottle stimulation, applied imiquimod (IMQ), ligand TLR7/8 effective potent immune activator, on dorsal to induce...

10.1002/jlb.3ma0320-363rr article EN Journal of Leukocyte Biology 2020-05-18

Psoriasis is a common autoimmune disease. Acupuncture-related techniques have been widely used to treat psoriasis since its ability engage neuronal function, the immune system, and other systems well documented. This study aimed investigate compare effects of three acupuncture-related in psoriasis-like skin inflammatory responses explore possible involved mechanisms. Imiquimod (IMQ)-induced mice were treated with acupuncture needling, electroacupuncture, or fire acupuncture. Methotrexate...

10.1155/2019/4706865 article EN Evidence-based Complementary and Alternative Medicine 2019-07-29

This study aims to explore the association between outdoor artificial light at night (ALAN) exposure and gestational diabetes mellitus (GDM).

10.3389/fpubh.2024.1396198 article EN cc-by Frontiers in Public Health 2024-04-10

Introduction: The incidence of psoriasis vulgaris is increasing worldwide. Chronic recurrence the disease, as well accompanying cardiovascular metabolic syndrome, and depression has affected physical mental health these patients. Psoriasis a difficult major disease in dermatology field. Short-term curative effects using conventional therapy for made strides. However, traditional Chinese medicine (TCM) treatment long-term advantages but lacks scientific clinical evidence its use. This study...

10.1097/md.0000000000021913 article EN cc-by-nc Medicine 2020-10-06

At present, acupuncture-related practices have been widely used to treat psoriasis. In our study, we investigated the effect and explored mechanism of electroacupuncture (EA) on acupoints Baihui (DU20) Xuehai (SP10) for treatment Imiquimod-induced psoriasis-like mouse model was in this study. Mice were treated with at DU20 SP10 (depth 2-3 mm, frequency 2/15 Hz, intensity 0.5-1.0 mA, 10 min/day). The severity lesions each group assessed. addition, histological analysis performed. levels...

10.1016/j.jtcme.2023.07.005 article EN cc-by-nc-nd Journal of Traditional and Complementary Medicine 2023-07-20

Abstract BACKGROUND: Abnormal neuroimmune regulation is involved in the occurrence and development of psoriasis. The elevated levels neurotransmitters skin locally promote activation immune cells by binding to their corresponding receptors, leading inflammation psoriasis lesions. As an important neurotransmitter receptor, Neurokinin-1 Receptors (NK-1R) can bind a variety ligands intensify maintain inflammatory response However, its specific role needs be further elucidated. METHODS:...

10.21203/rs.3.rs-2729879/v1 preprint EN cc-by Research Square (Research Square) 2023-03-30

Pneumonia is not only an acute lung infection but also a chronic disease that susceptible and recurrent. Children are to pneumonia, which affects their growth development. Immune disorders unrepaired alveolar mucosal epithelium following pneumonia cause injury. The mechanism of injury unknown lacks animal models for reference. Therefore, we aim develop the mouse model simulate pathological process children. 3-week-old mice were intratracheal instillation lipopolysaccharide (LPS) every other...

10.2139/ssrn.4040021 article EN SSRN Electronic Journal 2022-01-01
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