A5103046525- Trace Elements in Health
- Aluminum toxicity and tolerance in plants and animals
- Heavy Metal Exposure and Toxicity
- Migraine and Headache Studies
- Neurological diseases and metabolism
- Neurological Disorders and Treatments
- Advanced Neuroimaging Techniques and Applications
- Extraction and Separation Processes
- Medical Research and Treatments
- Neurological Disease Mechanisms and Treatments
- Trigeminal Neuralgia and Treatments
- Iron Metabolism and Disorders
- Traditional Chinese Medicine Analysis
- Liver Disease and Transplantation
- Acupuncture Treatment Research Studies
- Multi-Criteria Decision Making
- Abdominal vascular conditions and treatments
- Rocket and propulsion systems research
- Energetic Materials and Combustion
- Ferroptosis and cancer prognosis
- Fuzzy Systems and Optimization
- Alzheimer's disease research and treatments
- SARS-CoV-2 and COVID-19 Research
- Healthcare and Venom Research
- Cerebrovascular and Carotid Artery Diseases
Anhui University of Traditional Chinese Medicine
2014-2024
National University of Singapore
2023
Deleted Institution
2023
Second Affiliated Hospital of Jilin University
2017
Anhui University
2015
Acupuncture has been recommended as an alternative therapy for migraine. Emerging evidence suggests that the 5-HT7 receptor (5-HT7R) plays a significant facilitatory role in descending modulation migraine pathophysiology, and activation of 5-HT7R pathway is involved central sensitisation.To investigate ability electroacupuncture (EA) to ameliorate sensitisation via pain pathways using rat model induced by repetitive dural electrical stimulation (DES).64 male Sprague-Dawley rats were randomly...
Splenomegaly and pancytopenia are common in Wilson's disease (WD) splenectomy is one of the conventional treatments for splenomegaly associated pancytopenia. However, remained controversial hypersplenism WD as it was reported that leaded to serious emotional neurological deterioration patients with hypersplenism. In current study, we present our experiences 70 who had undergone splenectomy, outlining safety efficacy WD. The clinical database hospital between 2009 2013 were reviewed...
Abstract Background Even though recent research has achieved significant advancement in the development of therapeutic approaches for Wilson’s diseases (WD), current treatment options available WD are still limited, especially patients with neurological symptoms. This study is intended to compare symptoms receiving either combined sodium 2, 3-dimercapto-1-propane sulfonate (DMPS) and zinc or D-penicillamine (DPA) monotherapy as first-line therapy, identify more effective approach. Methods...
This study investigates levels of cuproptosis markers in Wilson disease (WD) and their role the occurrence development WD. We retrospectively collected clinical data from 76 patients with Leipzig score ≥ 4 hospitalized First Affiliated Hospital Anhui University Chinese Medicine January 2023 to September 2023. The participants were given copper chelators (sodium dimercaptosulphonate (20 mg·kg −1 ), courses treatment, 32 days). indicators (ALT, AST, ALP, HA, LN, PIIINP, CIV, liver stiffness...
The primary objective of this study was to assess whether Zhengtian Capsule non-inferior flunarizine in efficacy and safety profile for prevention migraine adults. This a double-dummy, double-blind, multicenter, positive drug (flunarizine), parallel randomized controlled, clinical trial. Patients (n = 360) were 1:1 receive either or flunarizine, including 12 weeks’ intervention 4 follow-up. outcome measure responder rate (defined as the percentage subjects treatment group with 50 % greater...
The clinical data of safety and efficacy a combined treatment with dimercaptosuccinic acid (DMSA) Zinc 2 years' follow-up in 60 neurological Wilson's disease (WD) patients was retrospectively analyzed. All the included present study were newly diagnosed initialized D-penicillamine (DPA) but found to have either deterioration or allergy, their switched DMSA Zinc. Fifty-one (85%) had symptoms improved 1 years after treatment, 7 (11.67%) experienced stable condition, (3.33%) suffered symptoms....
To investigate the effect and safety of Gandouling plus low-dose D-penicillamine for treating patients with Wilson's disease (WD) who have neurological symptoms. WD symptoms were divided into two groups: a treatment group (n = 53) control 50). The received anti-copper therapy combination (10 mg/kg), whereas was conventional dose (20 mg/kg) monotherapy. clinical efficacies, adverse reactions, results various hematological biochemical investigations recorded analyzed statistically. Overall,...
Aim: Hypersplenism can occur in patients with Wilson's disease (WD). Surgical splenectomy is a conventional treatment for this condition; however, emotional and neurological deterioration may follow splenectomy. In recent years, partial splenic embolization (PSE) has been increasingly performed as nonsurgical alternative hypersplenism. The aim of study was to evaluate the effectiveness safety PSE compared hypersplenism WD patients. Methods: Fifty were randomly divided into two groups (group...
Neuroimaging studies in Wilson's disease (WD) have identified various alterations white matter (WM) microstructural organization. However, it remains unclear whether these are localized to specific regions of fiber tracts, and what diagnostic value they might have. The purpose this study is explore the spatial profile WM abnormalities along defined tracts WD its clinical relevance.Ninety-nine patients with (62 men 37 women) 91 age- sex-matched controls (59 32 were recruited take part...
Abstract Background: Even though recent research has achieved significant advancement in the development of therapeutic approaches for Wilson’s diseases (WD), current treatment options available neurological symptoms WD are significantly limited and yet to be standardized. Objective: The aim this study was compare course patients with receiving either combined sodium 2, 3-dimercapto-1-propane sulfonate (DMPS) zinc or D-penicillamine (DPA) monotherapy as first-line therapy. Methods: case...
There are a number of symptoms associated with Wilson's disease (WD), including motor function damage. The neuropathological mechanisms underlying impairments in WD are, however, little understood. In this study, we explored changes the execution network topology WD.We conducted resting-state functional magnetic resonance imaging (fMRI) on 38 right-handed individuals, 23 patients and 15 healthy controls same age. Based graph theory, was constructed analyzed. global, nodal, edge topological...
Background Wilson’s disease (WD) is a rare hepatic and neurological disorder，23003132cwhich can dramatically worsen by traumatic injuries, surgeries, infections. No studies have reported safety data of severe acute respiratory syndrome coronavirus 2 (People’s Republic ChinaSARS-CoV-2) vaccination in WD patients. We aimed to investigate the SARS-CoV-2 status post-vaccination adverse events
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Abstract Background: Even though recent research has achieved significant advancement in the development of therapeutic approaches for Wilson’s diseases (WD), current treatment options available WD are still limited, expecially patients with neurological symptoms. Objective: The aim this study was to compare course symptoms receiving either combined sodium 2, 3-dimercapto-1-propane sulfonate (DMPS) and zinc or D-penicillamine (DPA) monotherapy as first-line therapy. Methods: case records 158...
Abstract Background: Even though recent research has achieved significant advancement in the development of therapeutic approaches for Wilson’s diseases (WD), current treatment options available neurological symptoms WD are significantly limited and yet to be standardized. Objective: The aim this study was compare course patients with receiving either combined sodium 2, 3-dimercapto-1-propane sulfonate (DMPS) zinc or D-penicillamine (DPA) monotherapy as first-line therapy. Methods: case...