A5032587750- Trauma and Emergency Care Studies
- Pelvic and Acetabular Injuries
- Abdominal Trauma and Injuries
- Urological Disorders and Treatments
- Trauma Management and Diagnosis
- Hernia repair and management
- Emergency and Acute Care Studies
- Food Quality and Safety Studies
- Nutrition, Health and Food Behavior
- Pregnancy-related medical research
- Congenital Diaphragmatic Hernia Studies
- Injury Epidemiology and Prevention
- Cardiovascular Issues in Pregnancy
- Endometriosis Research and Treatment
- Acute Ischemic Stroke Management
- Case Reports on Hematomas
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Congenital Anomalies and Fetal Surgery
- Radiomics and Machine Learning in Medical Imaging
- Nosocomial Infections in ICU
- Maternal and fetal healthcare
- Aortic Disease and Treatment Approaches
- Consumer Perception and Purchasing Behavior
- Ureteral procedures and complications
- Reproductive Health and Contraception
Gachon University Gil Medical Center
2015-2025
Gachon University
2013-2025
Chosun University
2021-2024
Kettering University
2024
Memorial Sloan Kettering Cancer Center
2024
Chungnam National University Hospital
2011-2024
Bucheon University
2023
Soonchunhyang University Hospital
2023
Korea University
2022-2023
Korea University Medical Center
2022-2023
Peroxisome proliferator-activator receptor (PPAR) γ is a nuclear hormone that regulates glucose homeostasis, lipid metabolism, and adipocyte function. PPARγ target for thiazolidinedione (TZD) class of drugs which are widely used the treatment type 2 diabetes. Recently, lobeglitazone was developed as highly effective TZD with reduced side effects by Chong Kun Dang Pharmaceuticals. To identify structural determinants high potency agonist, we determined crystal structures ligand binding domain...
Background/Objectives: To compare the outcomes of single-port assessment laparoscopic surgery (SPALS) and single-site robotic (SSRS) for benign gynecological diseases. Methods: The clinical data 367 patients who underwent gynecologic at Sejong Chungnam National University Hospital from October 2020 to December 2023 were analyzed retrospectively. Of these patients, 197 received SPALS while 170 SSRS. group comprise 87 hysterectomies, 107 adnexal surgeries (44 cystectomies, 63 adnexectomies) 1...
Background/Objectives: The Geriatric Trauma Outcome Score (GTOS) is used to predict in-hospital mortality in geriatric patients with trauma. However, its applicability elderly multiple traumas and severe traumatic brain injury (TBI) remains poorly understood. This study aimed evaluate the predictive accuracy of GTOS TBI assess performance mild TBI. Methods: We retrospectively analyzed 1283 trauma (aged ≥ 65 years) treated at a regional center from 2019 2023. Patients were stratified into...
Background/Objectives: Trauma remains a leading cause of morbidity and mortality worldwide, significantly affecting younger aging populations. The regional trauma center establishment in South Korea 2014 marked pivotal advancement the national care system. This study reviews data from Incheon Regional Center, analyzing patient demographics, injury mechanisms, outcome trends. Methods: retrospective analysis included 32,025 patients with treated at Center to 2023. Data Korean Database Injury...
Background Spread through air spaces (STAS) has recently been demonstrated to exhibit a negative impact on lung adenocarcinoma prognosis. However, most of these studies investigated STAS in nonmucinous adenocarcinoma. Here, we the incidence invasive mucinous (IMA) and evaluated whether tumor was risk factor disease recurrence IMA. We also examined clinicoradiologic factors patients with IMA harboring STAS. Methods reviewed pathologic specimens imaging characteristics primary tumors from 132...
Purpose Trauma is the top cause of death in people under 45 years age. Deaths from severe trauma can have a negative economic impact due to loss belonging socio-economically active age groups. Therefore, efforts reduce mortality rate patients are essential. The purpose this study was investigate preventable and identify factors healthcare-related challenges affecting mortality. Ultimately, these findings will help improve quality care. Methods We analyzed deaths 411 who presented Gachon...
Background and Objectives:The pathogenesis of hyponatremia (serum sodium <135 mEq/L) in Kawasaki disease (KD) remains unclear.We investigated the clinical significance hyponatremia, role interleukin (IL)-6 IL-1β development syndrome inappropriate antidiuretic hormone secretion (SIADH) KD.Subjects Methods: Fifty KD patients were prospectively enrolled analyzed for laboratory variables according to presence or SIADH.Results: Thirteen (26%) had 6 these SIADH.In with percentage neutrophils (%...
The purpose of this study was to evaluate the prognostic relevance a modified 3-point MRI-based tumor regression grading system incorporating DWI for patients with locally advanced rectal cancer after preoperative chemoradiotherapy (CRT).Between March 2012 and September 2013, 118 consecutively registered middle or lower who underwent CRT followed by surgery were enrolled in retrospective study. Two radiologists consensus assessed MRI grade (mrTRG) based on T2-weighted images high b value DW...
We investigated the patterns and timing of recurrence death as well prognostic factors based on clinicopathological radiological in patients who underwent surgical treatment for invasive mucinous adenocarcinoma (IMA).We reviewed findings including spread through air spaces (STAS) CT IMA such morphology, solidity, margin, well-defined heterogeneous ground-glass opacity, angiogram, bronchogram signs from 121 consecutive resection. Prognostic disease-free survival (DFS) overall (OS) were...
To investigate the long-term results of penetrating keratoplasty (PK) in patients with keratoconus (KC) and to evaluate factors that might influence final visual outcome.We retrospectively reviewed data all clinical KC who had undergone PK by a single corneal surgeon center from May 1980 December 2005. The age patients, preoperative best-corrected acuity (BCVA), thickness, death preservation time, transplantation time were recorded. Additionally, postoperative complications such as graft...
Trichomonas vaginalis causes lesions on the cervicovaginal mucosa in women; however, its pathogenesis remains unclear. We have investigated involvement of endoplasmic reticulum (ER) induction apoptosis by T. and molecular mechanisms human cervical cancer SiHa cells.Apoptosis, reactive oxygen species (ROS) production, mitochondrial membrane potential (MMP), ER stress response Bcl-2 family protein expression were evaluated using immunocytochemistry, flow cytometry,...
<b><i>Background:</i></b> Medial temporal atrophy (MTA) is a recognized marker of Alzheimer’s disease (AD), and white matter hyperintensities (WMH) are frequently observed on MRI AD. The purpose this study was to understand the role WMH in MTA. <b><i>Methods:</i></b> Subjects were 94 probable AD patients 51 cognitively normal subjects. assessed based severity deep (DWMH) periventricular (PWMH). Each structural volume evaluated using Individual...
Background:The Acute Physiology and Chronic Health Evaluation (APACHE) II scoring system the Sequential Organ Failure Assessment (SOFA) are widely used for critically ill patients.We evaluated whether APACHE score SOFA predict outcome trauma patients in intensive care unit (ICU).Methods: We retrospectively analyzed admitted to ICU a single center between January 2014 December 2015.The was figured out based on data acquired from first 24 hours of admission; 3 days ICU.A total 241 were...
Pulmonary infection is a major cause of mortality in immunocompromised patients. Immunosuppression can be divided into neutropenia, humoral immunodeficiency, and cellular immunodeficiency. these patients typically depends on the type, duration, degree often nonspecific, both clinically radiologically, but certain type pulmonary may provide typical radiological features helpful for definitive diagnosis. Therefore, it essential to incorporate clinical information narrow down differential...
Abstract Background Immunoglobulin G4-related disease (IgG4-RD) is an immune-mediated fibro-inflammatory condition characterized by high serum IgG4 concentrations and tissue infiltration IgG4-positive plasma cells. Reports have demonstrated that IgG4-RD affects various organs, including the pancreas, kidney, lung, thyroid, lacrimal salivary glands. In nervous system, hypertrophic pachymeningitis hypophysitis are mainly related to IgG4-RD; however, peripheral neuropathy involvement unusual....
Purpose We aimed to evaluate the trauma volume and performance indicators during first 5-year period of operation in a single regional center. Methods analyzed prospectively collected data from Korean Trauma Data Bank for center between January 2014 December 2018. More than 250 variables were analyzed. calculated predicted survival rates using injury severity score (TRISS) method. Results In total, there 16,103 admissions 5 years; activation was performed 5,105 these cases. Over 70% patients...
Abstract Background No standard treatment guidelines have been established for postpartum hemorrhage (PPH). We aimed to assess the differences in outcomes and prognoses between patients with PPH who underwent surgical non-surgical treatment. Methods This retrospective study included 230 diagnosed at two referral hospitals August 2013 October 2023. The were divided into (group 1, n = 159) intervention groups 2, 71). A subgroup analysis was performed by dividing group immediate ( 45) delayed...
Purpose: Traumatic lumbar hernia is rare, thus making diagnosis and proper treatment challenging.Accordingly, we aimed to investigate the clinical manifestations management strategies of traumatic hernias.Methods: The medical records patients with treated at Gachon University Gil Hospital from March 2006 February 2015, were retrospectively reviewed.Results: We included 5 men 4 women (mean age, 55 years; range, 23-71 years).In 8 patients, most injuries caused by motor vehicle collisions,...