A5058723738- Respiratory Support and Mechanisms
- Intensive Care Unit Cognitive Disorders
- COVID-19 Clinical Research Studies
- Cardiac Arrest and Resuscitation
- Long-Term Effects of COVID-19
- Global Cancer Incidence and Screening
- Sepsis Diagnosis and Treatment
- Sarcoma Diagnosis and Treatment
- Airway Management and Intubation Techniques
- Colorectal Cancer Screening and Detection
- Neuroblastoma Research and Treatments
- Cancer Immunotherapy and Biomarkers
- Renal cell carcinoma treatment
- Glioma Diagnosis and Treatment
- Neonatal Respiratory Health Research
- Brain Metastases and Treatment
- Testicular diseases and treatments
- Lung Cancer Treatments and Mutations
- Family and Patient Care in Intensive Care Units
- RFID technology advancements
- Cancer Treatment and Pharmacology
- COVID-19 and healthcare impacts
- Multiple and Secondary Primary Cancers
- Tumors and Oncological Cases
- Lung Cancer Research Studies
Secretaria de Salud
2025
Hospital Regional de Alta Especialidad del Bajío
2025
Hospital Del Mar
2021-2024
Hospital del Mar Research Institute
2023-2024
Universitat Pompeu Fabra
2024
Indra (Spain)
2018-2023
Centre Léon Bérard
2004-2021
MC2 Therapeutics (Denmark)
2020
Hospital de Sant Pau
2014-2018
Centre Hospitalier Chrétien
2016
Purpose The effectiveness of nonsteroid topical agents for the prevention acute dermatitis during adjuvant radiotherapy breast carcinoma has not been demonstrated. goal this study was to compare calendula (Pommade au Calendula par Digestion; Boiron Ltd, Levallois-Perret, France) with that trolamine (Biafine; Genmedix France), which is considered in many institutions be reference agent. Patients and Methods Between July 1999 June 2001, 254 patients who had operated on cancer were receive...
Mechanical ventilation with a tidal volume (VT) of 6 mL/kg/predicted body weight (PBW), to maintain plateau pressure (Pplat) lower than 30 cmH2O, does not completely avoid the risk ventilator induced lung injury (VILI). The aim this study was evaluate safety and feasibility strategy consisting very low VT combined extracorporeal carbon dioxide removal (ECCO2R).In fifteen patients moderate ARDS, reduced from baseline 4 mL/kg PBW while PEEP increased target pressure--(Pplat) between 23 25...
•A reduction of the number cancer patients attending centers was observed in France from January to July 2020.•This only for newly diagnosed patients.•The new diagnosis more pronounced women, breast cancer, and prostate nonmetastatic cancer.•No compensation last months 2020. The magnitude delays may be larger within same country.•An estimation excess death resulting these is presented. BackgroundThe impact first coronavirus disease 2019 (COVID-19) wave on patient management measured...
PURPOSE The purpose of this study was to investigate the prognostic value time relapse in 188 adult patients with intermediate- or high-grade non-Hodgkin's lymphoma (NHL) included on Parma trial at their first relapse. PATIENTS AND METHODS median follow-up these is 102 months after registration onto study. Time calculated from initial diagnosis, and a cutoff 12 used separate 77 defined as early 111 late RESULTS Patients relapses had significantly different overall response rates salvage...
Rationale: When compared with VenturiMask after extubation, high-flow nasal oxygen provides physiological advantages. Objectives: To establish whether prevents endotracheal reintubation in hypoxemic patients VenturiMask. Methods: In this multicenter randomized trial, 494 exhibiting PaO2:FiO2 ratio ⩽ 300 mm Hg extubation were randomly assigned to receive or oxygen, the possibility apply rescue noninvasive ventilation before reintubation. High-flow use group was not permitted. Measurements and...
Non-invasive oxygenation strategies have a prominent role in the treatment of acute hypoxemic respiratory failure during coronavirus disease 2019 (COVID-19). While efficacy these therapies has been studied hospitalized patients with COVID-19, clinical outcomes associated oxygen masks, high-flow therapy by nasal cannula and non-invasive mechanical ventilation critically ill intensive care unit (ICU) remain unclear.
A phase II trial was designed to determine the efficacy and tolerance of interleukin-2 (IL-2), interferon alfa-2a (IFNalpha), fluorouracil (5-FU) in patients with metastatic renal cell carcinoma.One hundred eleven were included. Patients received subcutaneous IL-2 9 x 10(6) IU daily for 6 days IFNalpha on 1, 3, 5 every other week 8 weeks. 5-FU administered through a continuous infusion at 600 mg/m2 consecutive 1 4 weeks.The response rate 1.8% (95% confidence interval [CI], 0% 4.3%) only two...
High-dose chemotherapy (HD-CT) is able to circumvent platinum resistance of resistant/refractory germ-cell tumors (GCTs), but expectancy cure remains low. New strategies are needed with new drugs and a sequential approach.Patients relapsed poor-prognosis GCTs were scheduled receive two cycles combining epirubicin paclitaxel (Taxol) followed by three consecutive HD-CT supported stem cell transplantation [one course cyclophosphamide, 3 g/m(2) + thiotepa, 400 mg/m(2), ICE regimens (ifosfamide,...
In acute respiratory distress syndrome (ARDS) patients, it has recently been proposed to set positive end-expiratory pressure (PEEP) by targeting transpulmonary pressure. This approach, which relies on the measurement of absolute esophageal (Pes), used in supine position (SP) and not investigated prone (PP). Our purposes were assess Pes-guided strategy PEEP SP PP as compared with a PEEP/FIO2 table explore early (1 h) late (16 effects lung chest wall mechanics. We performed prospective,...
Second primary cancers (SPCs) are diagnosed in over 5% of patients after a first cancer (FPC). We explore here the impact immune checkpoint inhibitors (ICIs) given for an FPC on risk SPC different age groups, types and treatments.The files 46 829 with Centre Léon Bérard from 2013 to 2018 were analyzed. Structured data extracted electronic patient records screened using natural language processing tool, validation manual screening 2818 patients. Univariate multivariate analyses incidence...
ABSTRACT Background Rhabdomyosarcoma (RMS), a rare malignant tumor, frequently affects pediatric patients, with 35%–40% occurring in the head and neck. This study analyzes clinicopathologic profile of neck rhabdomyosarcomas from Brazil, Guatemala, Mexico, South Africa. Methods We reviewed 44 cases 10 Oral Maxillofacial Pathology services, conducting immunohistochemical analyses desmin, myogenin, Myo‐D1, Ki67, quantification via QuPath software. Cases ≥ 50% myogenin expression were tested for...
End-inspiratory pause (EIP) prolongation decreases dead space-to-tidal volume ratio (Vd/Vt) and PaCO2. We do not know the physiological benefits of this approach to improve respiratory system mechanics in acute distress syndrome (ARDS) patients when mild hypercapnia is no concern.The investigation was conducted an intensive care unit a university hospital, 13 ARDS were included. The study designed three phases. First phase, baseline measurements taken. Second EIP prolonged until one...
In children over 1 year of age with metastatic neuroblastoma, clearance metaiodobenzylguanidine (MIBG) skeletal uptake after four courses induction chemotherapy is one the most powerful prognostic factors. How subjective quantification MIBG uptake, and can earlier scintigraphy separate good bad responders?The data from 47 patients who received uniform therapy were reviewed. A novel scoring system update intensity was proposed. Initial, intermediate (after two courses), final courses)...
In this paper we present first measurement results the use of ITS-G5 technology for Smart Train Composition Coupling. Intelligent Transport System (ITS-G5) communication link has been already Train-to-Train (T2T) communications. The SCOTT(Secure COnnected Trustable Things) project focuses on Vehicle to (V2V) communications as one main development lines in Coupling (STCC) case and additionally Infrastructure bidirectional (V2I/I2V) Warning (TWS) critical Areas case. V2V SCOTT decentralization...
Weaning patients from mechanical ventilation is crucial in the management of acute respiratory failure (ARF). Spontaneous breathing trials (SBT) are used to assess readiness for extubation, but extubation remains a challenge. Diaphragmatic function, measured by electrical activity diaphragm (EAdi), may provide insights into weaning outcomes.
<i>Purpose:</i> To investigate the efficacy and safety of FOLFOX-4 regimen for patients with metastatic renal cell carcinoma (MRCC). <i>Patients Methods:</i> Fifty-nine (median age 59 years) pre-treated or not by cytokines (29 vs. 30) received every 2 weeks. <i>Results:</i> Three minor responses, no complete partial responses were obtained. The median progression-free survival was 3 months (95% CI: 2.6–3.4), 10.6 8.7–12.4), difference between others....