A5068316401- Renal cell carcinoma treatment
- Prostate Cancer Diagnosis and Treatment
- Prostate Cancer Treatment and Research
- Bladder and Urothelial Cancer Treatments
- Renal and related cancers
- Urinary and Genital Oncology Studies
- Urologic and reproductive health conditions
- Urological Disorders and Treatments
- Multiple and Secondary Primary Cancers
- Cancer Genomics and Diagnostics
- Radiopharmaceutical Chemistry and Applications
- Urinary Bladder and Prostate Research
- Renal and Vascular Pathologies
- MRI in cancer diagnosis
- Pediatric Urology and Nephrology Studies
- Cancer Immunotherapy and Biomarkers
- Synthesis and Biological Evaluation
- Macrophage Migration Inhibitory Factor
- Cancer, Lipids, and Metabolism
- Radiomics and Machine Learning in Medical Imaging
- Inflammatory Biomarkers in Disease Prognosis
- Pelvic floor disorders treatments
- Ferroptosis and cancer prognosis
- Pancreatic and Hepatic Oncology Research
- Urinary Tract Infections Management
Sungkyunkwan University
2016-2025
Samsung Medical Center
2016-2025
Creative Commons
2023
Memorial Sloan Kettering Cancer Center
2021
Seoul National University Bundang Hospital
2021
Government of the Republic of Korea
2020
University of Ulsan
2015-2019
Asan Medical Center
2015-2019
Ulsan College
2015-2019
St. Vincent's Hospital
2019
Abstract Missense somatic mutations in IDH1 gene affecting codon 132 have recently been reported glioblastoma multiforme (GBM) and other gliomas. The recurrent nature of the same amino acid strongly suggests that may play important roles pathogenesis glial tumors. aim this study was to see whether occur human cancers besides We also attempted confirm occurrence GBM Korean patients. analyzed 1,186 cancer tissues from various origins, including carcinomas breast, colon, lung, stomach,...
NGF and PGs in the bladder can be affected by pathological changes these detected urine. We investigated urinary women with OAB.The study groups included 65 OAB 20 without symptoms who served as controls. Evaluation patient history, urinalysis, a voiding diary urodynamic studies. Urine samples were collected. NGF, PGE2, PGF2alpha PGI2 measured using enzyme-linked immunosorbent assay compared between groups. In addition, correlations PG, parameters patients examined.Urinary PGE2 significantly...
The purpose of our study was to prospectively evaluate whether MRI before an initial transrectal ultrasound-guided biopsy contributed detection prostate cancer in patients with high prostate-specific antigen (PSA) level and no previous biopsy.Men abnormal digital rectal examination or PSA were enrolled this prospective randomized study. Participants randomly allocated into two groups; the group underwent 3-T then a knowledge location. non-MRI did not undergo biopsy. rate positive core...
Resistance of bladder cancer to cisplatin is a major obstacle successful treatment. In the current study, we investigated apoptotic effects curcumin and co-treatment in 253J-Bv(p53 wild-type) T24(p53 mutant) cancer. We found that primarily targets reactive oxygen species(ROS) extracellular regulated kinase(ERK) signaling during apoptosis induction The rate 253J-Bv T24 cells co-treated with was increased compared exposed single-agent treatment conditions. Also, caspase-3 activation ROS...
Background The anti‐cancer activities of curcumin are well‐documented from preclinical studies using prostate cancer models. Our objective was to evaluate the activity oral in patients with cancer. Methods This randomized, double‐blind, placebo‐controlled trial performed on who received intermittent androgen deprivation (IAD). Participants finished first on‐treatment period IAD were randomized into a or placebo group. took (1440 mg/day) for six months and followed up until beginning second...
Abstract Aim: Nerve growth factor (NGF) and prostaglandins (PG) in the urinary bladder can be affected by pathology of bladder, this change noted urine. This study was performed to investigate changes NGF PG male patient with overactive (OAB) symptoms. Methods: The group included 75 patients OAB symptoms 20 males without as controls. Evaluation history‐taking, urinalysis, International Prostate Symptom Score (IPSS) urodynamic study. NGF, PGE 2 , PGF 2α PGI levels voided urine were analyzed...
We evaluated the accuracy of preoperative multiparametric 3.0-T magnetic resonance imaging for local staging prostate cancer and its influence in decision to preserve neurovascular bundles at robotic assisted laparoscopic radical prostatectomy.The study included 353 patients who had confirmed underwent prostatectomy between 2008 2011. The extent bundle sparing was initially determined on basis clinical information nerve surgical plan reevaluated after review report. value prediction...
No AccessJournal of UrologyAdult Urology1 Mar 2016Percutaneous Kidney Biopsy for a Small Renal Mass: A Critical Appraisal Results Hwang Gyun Jeon, Seong Il Seo, Byong Chang Jeong, Soo Hyun Moo Lee, Han-Yong Choi, Cheryn Song, Jun Hyuk Hong, Choung-Soo Kim, Hanjong Ahn, and In Gab Jeong JeonHwang Jeon , SeoSeong Seo JeongByong JeonSeong LeeHyun Lee ChoiHan-Yong Choi SongCheryn Song HongJun Hong KimChoung-Soo Kim AhnHanjong Ahn JeongIn View All Author...
OBJECTIVE To investigate the expression of muscarinic and purinergic receptors in rat urothelium, changes their distribution following detrusor overactivity induced by bladder outlet obstruction (BOO). MATERIALS AND METHODS Thirty Sprague‐Dawley rats were divided into control (10) BOO groups (20). Partial was for 3 weeks assessed cystometrography. A portion stained using immunofluorescence M 2 receptors, P2X receptors. The remainder dissected urothelium smooth muscle layer, receptor proteins...
The aim of this study was to evaluate the efficacy and safety retrograde intrarenal surgery (RIRS) for treatment renal stones analyze predictive factors stone-free.We retrospectively reviewed records patients who underwent RIRS from January 2000 July 2009. We identified 66 RIRSs (63 with 3 bilateral stones) collected data. Stone-free success were respectively defined as no visible clinically insignificant residual less than mm on postoperative imaging; stone-free evaluated.Of stones, 18...
Diagnostic ureterorenoscopy is powerful tool to confirm upper tract urothelial cancer (UTUC). However, URS and associated manipulation may be related the risk of intravesical recurrence (IVR) following radical nephroureterectomy (RNU). We aimed investigate whether preoperative would increase IVR after RNU in patients with UTUC. performed a retrospective analysis 630 who had bladder cuff excision due was 282 (44.7%). Patients were divided into two groups according URS. Survival multivariate...
Objectives To determine the effect of visceral obesity on prognosis advanced renal cell carcinoma patients undergoing nephrectomy. Methods We reviewed clinicopathological data 2187 who underwent nephrectomy for (localized [T1–2, N0, M0], n = 1738 [79.5%]; [T3–4, any N and M], 449 [20.5%]) at Samsung Medical Center, Seoul, Korea. The fat area subcutaneous were determined level umbilicus computed tomograms obtained before surgery. Patients categorized as either viscerally obese or non‐obese...
Radical prostatectomy (RP) is the main treatment of prostate cancer (PCa). Biochemical recurrence (BCR) following RP remains first sign aggressive disease; hence, better assessment potential long-term post-RP BCR-free survival crucial. Our study aimed to evaluate a combined clinical-deep learning (DL) model using multiparametric magnetic resonance imaging (mpMRI) for predicting in PCa. A total 437 patients with PCa who underwent mpMRI followed by between 2008 and 2009 were enrolled;...
Abstract The World Health Organization/International Society of Urological Pathology (WHO/ISUP) grading renal cell carcinoma (RCC) is classified from grade 1–4, regardless subtype. National Comprehensive Cancer Network (NCCN) guidelines (2022) state that if there an adverse pathological feature, such as 3 or higher RCC in stage 1 patients, more rigorous follow-up imaging recommended. However, the do not provide specific treatment policies by tumor grade. Therefore, this study attempted to...
Purpose: The aim of our study was to compare early complication rates between the robot-assisted radical cystectomy (RARC) and open (ORC) using a standardized reporting system. Patients Methods: From September 2008 March 2011, 35 104 patients underwent ORC RARC, respectively. Demographics perioperative data on all were reviewed retrospectively compared two groups. All complications categorized modified Clavien We also sought identify independent predictive factors grade II or greater...
We sought to investigate the impact of preoperative and postoperative membranous urethral length (MUL) on urinary continence using 3 Tesla (3T) magnetic resonance imaging (MRI) after robotic-assisted radical prostatectomy (RARP).Between 2008 2013, 190 men with RARP underwent MRI. Patients who received adjuvant radiotherapy or were lost followup excluded, leaving 186 patients eligible for analysis. Preoperative MUL was estimated from prostate apex penile bulb, while bladder neck bulb. no pads...