- HIV/AIDS Research and Interventions
- HIV, Drug Use, Sexual Risk
- Salmonella and Campylobacter epidemiology
- Antibiotic Resistance in Bacteria
- Sex work and related issues
- Escherichia coli research studies
- Tuberculosis Research and Epidemiology
- Adolescent Sexual and Reproductive Health
- Food Security and Health in Diverse Populations
- Pneumonia and Respiratory Infections
- HIV Research and Treatment
- Listeria monocytogenes in Food Safety
- Vibrio bacteria research studies
- Hepatitis C virus research
- Hepatitis B Virus Studies
- Pharmaceutical and Antibiotic Environmental Impacts
- HIV-related health complications and treatments
- Infectious Diseases and Tuberculosis
- Patient Satisfaction in Healthcare
- Healthcare cost, quality, practices
- Patient-Provider Communication in Healthcare
- Creative Drama in Education
- Lipid Membrane Structure and Behavior
- Hospital Admissions and Outcomes
- Viral gastroenteritis research and epidemiology
Centers for Disease Control and Prevention
2010-2024
National Center for HIV/AIDS Viral Hepatitis STD and TB Prevention
2016-2024
CDC Foundation
2023
Cornell University
2022
Advocate Illinois Masonic Medical Center
2021
Tampere University
2016-2020
National Center for Emerging and Zoonotic Infectious Diseases
2010-2011
Atlanta Research and Education Foundation
2010
United States Food and Drug Administration
2010
University of Georgia
2010
Nontyphoidal salmonellae (NTS) are important causes of community-acquired bloodstream infection. We describe patterns antimicrobial resistance among invasive NTS in the United States. compared isolates with those from stool submitted to National Antimicrobial Resistance Monitoring System (NARMS) 1996 2007. strains by serogroup and serotype. Of 19,302 isolates, 17,804 (92.2%) were or blood. these, 1,050 (5.9%) isolates. The median ages (ranges) patients without bacteremia 36 (<1 97) years 20...
Treatment of shigellosis with appropriate antimicrobial agents shortens duration illness and bacterial shedding, but resistance to commonly used is increasing.We describe patterns among Shigella isolates in the United States use linked data from Foodborne Diseases Active Surveillance Network (FoodNet) National Antimicrobial Resistance Monitoring System (NARMS). FoodNet sites send every 20th isolate NARMS laboratory for susceptibility testing.During 2000-2010, tested 1376 sites. Of 1118 (81%)...
Nontyphoidal Salmonella causes an estimated 1.2 million infections, 23,000 hospitalizations, and 450 deaths annually in the United States. Most illnesses are self-limited; however, treatment with antimicrobial agents can be life-saving for invasive infections.The Foodborne Diseases Active Surveillance Network National Antimicrobial Resistance Monitoring System collaborated on a prospective cohort study of patients nontyphoidal bloodstream gastrointestinal infections to determine differences...
Salmonella is a major bacterial pathogen transmitted commonly through food. Increasing resistance to antimicrobial agents (e.g., ceftriaxone, ciprofloxacin) used treat serious infections threatens the utility of these agents. Infection with antimicrobial-resistant has been associated increased risk severe infection, hospitalization, and death. We describe changes in among nontyphoidal United States from 1996 2009.
Abstract Background Tuberculosis (TB) elimination within the United States will require scaling up TB preventive services. Many public health departments offer care for latent tuberculosis infection (LTBI), although gaps in LTBI cascade are not well quantified. An understanding of these be required to design targeted interventions. Methods We conducted a cohort study through Epidemiologic Studies Consortium (TBESC) 15 local department (LHD) clinics across States. Data were abstracted on...
CTX-M-type beta-lactamases are increasing among US Enterobacteriaceae isolates. Of 2,165 non-Typhi Salmonella isolates submitted in 2007 to the National Antimicrobial Resistance Monitoring System, 100 (4.6%) displayed elevated MICs (≥2 mg/L) of ceftriaxone or ceftiofur. Three (serotypes Typhimurium, Concord, and I 4,5,12:i:-) contained bla(CTX-M-5), bla(CTX-M-15), bla(CTX-M-55/57), respectively.
Shigellosis is the third most common enteric bacterial infection in United States. Although typically self-limiting, empiric treatment often prescribed. Because of increasing antimicrobial resistance to Shigella, options are decreasing. Identifying patterns can inform recommendations. The goals our study were examine risk factors associated with Shigella and issues related Shigella. During June 2006-February 2009, we attempted interview all New York City patients reported have shigellosis....
Abstract We determined the prevalence of plasmid-mediated quinolone resistance mechanisms among non-Typhi Salmonella spp. isolated from humans, food animals, and retail meat in United States 2007. Six isolates collected humans harbored aac(6′)Ib-cr or a qnr gene. Most prevalent was qnrS1. No animal mechanism.
Objective. The Enhanced Comprehensive HIV Prevention Planning project was the first initiative of Centers for Disease Control and (CDC) to address goals National HIV/AIDS Strategy (NHAS). Health departments in 12 U.S. cities with a high prevalence AIDS conducted comprehensive program planning implemented cost-effective, scalable prevention interventions that targeted high-risk populations. We examined trends health department programs these during project. Methods. analyzed number people who...
Multivitamin-loaded and surface-modified liposomes tailored for simultaneous intestinal delivery of both lipophilic hydrophilic bioactives were synthesized from sunflower phosphatidylcholine (SFPC). Liposomes (SL) generated with the aid a novel, organic solvent free, environmentally benign process which utilizes venturi-based rapid expansion supercritical solution (Vent-RESS). Vitamins E C used as model demonstrated an average encapsulation efficiency 92 70 %, respectively. Synthesized...
Objectives. To examine state-level factors associated with late-stage HIV diagnoses in the United States.Methods. We examined by estimating negative binomial regression models. used 2013 to 2016 data from National Surveillance System (late-stage diagnoses), Behavioral Risk Factor (HIV testing), and American Community Survey (sociodemographics).Results. Among individuals 25 44 years old, a 5% increase percentage of state population tested for preceding 12 months was 3% decrease diagnoses....
Abstract Background Tuberculosis infection (TBI) and chronic hepatitis B virus (HBV) disproportionately affect non–US-born persons. Early identification treatment are critical to reduce transmission, morbidity, mortality, but little is known about screening in the United States. Methods We conducted a cross-sectional study large integrated California health system September 2022 assessing TBI HBV among persons aged ≥18 years who were born countries with high TB burden (TB disease incidence...
To increase understanding of community-acquired resistance, stool samples from 477 nonhospitalized persons in Maryland and Michigan, 2004 to 2008, were screened for ceftriaxone resistance. Seven (1.5%) yielded ceftriaxone-resistant Escherichia coli; one isolate was resistant all eight antimicrobial classes routinely tested: aminoglycosides, β-lactam/β-lactamase inhibitor combinations, cephems, penicillins, folate pathway inhibitors, phenicols, quinolones, tetracyclines. The extensively a...
Objectives HIV testing identifies persons living with and can lead to treatment, decreased risk behaviors, reduced transmission. The objective of our study was describe state-level trends in the general US adult population aged 18-64 years, for both ever tested previous 12 months. Methods Using 2011-2017 Behavioral Risk Factor Surveillance System data, we estimated percentage state population, plus District Columbia, years 50 states Columbia were grouped according prevalence 2011. We used...
Abstract Background Hepatitis B virus (HBV) infection and tuberculosis (TB) both disproportionately affect non-U.S.–born persons from countries with hepatitis surface antigen (HBsAg) seroprevalence ≥2% or TB incidence rates ≥20/100,000 population. Early identification treatment of chronic HBV are critical to reduce morbidity mortality, but little is known about screening among in the United States. Methods In a cross-sectional study using electronic health record data, we assessed practices...