A5025153056- Wheat and Barley Genetics and Pathology
- Genetic Mapping and Diversity in Plants and Animals
- Plant Molecular Biology Research
- Research in Cotton Cultivation
- Heavy metals in environment
- Plant nutrient uptake and metabolism
- Genetic and phenotypic traits in livestock
- Advanced biosensing and bioanalysis techniques
- Plant Genetic and Mutation Studies
- Pharmaceutical and Antibiotic Environmental Impacts
- Biopolymer Synthesis and Applications
- Plant tissue culture and regeneration
- Plant Virus Research Studies
- Coal Properties and Utilization
- Plant-Microbe Interactions and Immunity
- Coal and Its By-products
- Environmental Quality and Pollution
- Ubiquitin and proteasome pathways
- Plant Stress Responses and Tolerance
- Genetics and Plant Breeding
- Antibiotics Pharmacokinetics and Efficacy
- Coastal and Marine Management
- Marine and coastal ecosystems
- Mechanical Circulatory Support Devices
- Hemodynamic Monitoring and Therapy
Chinese Academy of Agricultural Sciences
2017-2025
Zhejiang Chinese Medical University
2024-2025
Cotton Research Institute
2020-2025
Zhengzhou University
2025
China Metallurgical Geology Bureau
2024
Henan Institute of Science and Technology
2011-2024
Henan Polytechnic University
2023
China Agricultural University
2021-2023
Zoucheng People's Hospital
2023
Tianjin Research Institute of Water Transport Engineering
2018-2022
Wheat breeding over the last 100 years has increased productivity by adapting genotypes to local conditions, but genomic changes and selection signals that caused phenotypic change during are essentially unknown. Studying understanding human of multiple important genes controlling key traits will promote wheat molecular breeding.A total 1152 diverse global materials were genotyped based on KASP markers from 47 grain yield, quality, adaptation, stress resistance. Significant variations...
Early targeted antibiotic therapy is crucial for improving the prognosis of immunocompromised patients with severe respiratory infections (SRIs) in intensive care unit (ICU). Metagenomic next-generation sequencing (mNGS) has shown significant value pathogen detection, but research on lower tract microorganisms remains limited. This study enrolled 234 SRIs ICU, and individuals were categorized into immunocompetent groups. We compared diagnostic performance mNGS using bronchoalveolar lavage...
ε-Poly-L-lysine (ε-PL) is a food additive produced by Streptomyces and widely used in many countries. Working with albulus FEEL-1, we established method to activate ε-PL synthesis successive introduction of multiple antibiotic-resistance mutations. Sextuple mutant R6 was finally developed screening for resistance six antibiotics 4.41 g/L shake flask, which 2.75-fold higher than the level parent strain. In previous study, constructed double-resistance mutant, SG-31, high production 3.83 59.50...
Abstract Background Fiber quality is an important economic trait of cotton, and its improvement a major goal cotton breeding. To better understand the genetic mechanisms responsible for fiber traits, we conducted genome-wide association study to identify mine fiber-quality-related quantitative loci (QTLs) genes. Results In total, 42 single nucleotide polymorphisms (SNPs) 31 QTLs were identified as being significantly associated with five traits. Twenty-five in previous studies, six novel...
Abstract In plants, glucose (Glc) plays important roles, as a nutrient and signal molecule, in the regulation of growth development. However, function Glc fiber development upland cotton (Gossypium hirsutum) is unclear. Here, using gas chromatography-mass spectrometry (GC-MS), we found that content fibers was higher than ovules during elongation stage. vitro ovule culture revealed lower concentrations promoted elongation, while had inhibitory effects. The hexokinase inhibitor...
Verticillium wilt (VW), Fusarium (FW) and Root-knot nematode (RKN) are the main diseases affecting cotton production. However, many reported quantitative trait loci (QTLs) for resistance have not been used agricultural practices because of inconsistencies in genetic background. The integration existing resources can facilitate discovery important genomic regions candidate genes involved disease resistance. Here, an improved comprehensive meta-QTL analysis was conducted on 487 resistant QTLs...
Soil salinization, which is primarily due to excessive Na+ levels, a major abiotic stress adversely affecting plant growth and development. The Na+/H+ antiporter (NHX) transmembrane protein mediating the transport of or K+ H+ across membrane modulate ionic balance plants in response salt stress. Research regarding NHXs has mainly focused on vacuolar-type NHX family members. However, biological functions endosomal-type remain relatively uncharacterized. In this study, 22 members were...
The SWEET (sugars will eventually be exported transporter) proteins, a family of sugar transporters, mediate diffusion across cell membranes. Pathogenic fungi can acquire sugars from plant cells to satisfy their nutritional demands for growth and infection by exploiting transporters. However, the mechanism underlying allocation in cotton plants infected Verticillium dahliae , causative agent wilt, remains unclear. In this study, observations colonization roots V. revealed that large number...
Fluid administration is widely used to treat hypotension in patients undergoing veno-venous extracorporeal membrane oxygenation (VV-ECMO). However, excessive fluid may lead overload can aggravate acute respiratory distress syndrome (ARDS) and increase patient mortality, predicting responsiveness of great significance for VV-ECMO patients. This prospective single-center study was conducted a medical intensive care unit (ICU) finally included 51 with ARDS the prone position (PP). Stroke volume...
ABSTRACTThe contamination of coal-mine soil by heavy metals is a widespread problem. This study analyzes the (Cu, Zn, Ni, Pb, Cr, Cd, and Hg) found in 33 surface samples from Xinzhuangzi, China restored coal-mining land used as cultivated land. The results show that selected elements were cumulative, especially for Cd. An index geo-accumulation indicates was practically uncontaminated Cu, Hg, to moderately contaminated Pb heavily Based on U.S. Environmental Protection Agency's ecological...
Hexaploid wheat consists of three subgenomes, namely, A, B, and D. These well-characterized ancestral genomes also exist at the diploid tetraploid levels, thereby rendering as a good model species for studying polyploidization. Here, we performed intra- inter-species comparative analyses its relatives to dissect polymorphism differentiation TaGW2 genes. Our results showed that genetic diversity decreased with progression from diploids tetraploids hexaploids. The strongest selection occurred...
Little attention has been paid to the problem of combined toxicity accumulated antibiotics on humans from food and clinical treatments. Therefore, we used human hepatocytes study joint four common antibiotics. The cytotoxicity enrofloxacin (ENR), with ciprofloxacin (CFX), florfenicol (FFC), or sulfadimidine (SMD) THLE-2 cells was determined by CCK-8 assays; then their evaluated using CalcuSyn 2.0. Dose-effect curves median-effect plots established large amounts data CI values were calculated...
Vacuolar sodium/proton (Na+/H+) antiporters (NHXs) can stabilize ion contents to improve the salt tolerance of plants. Here, GhNHX3D was cloned and characterized from upland cotton (Gossypium hirsutum). Phylogenetic sequence analyses showed that belongs vacuolar-type NHXs. The GhNHX3D-enhanced green fluorescent protein (eGFP) fusion localized on vacuolar membrane when transiently expressed in Arabidopsis protoplasts. quantitative real-time PCR (qRT-PCR) analysis induced rapidly response...
Ubiquitination is a post-translational regulatory mechanism that controls variety of biological processes in plants. The E3 ligases confer specificity by recognizing target proteins for ubiquitination. Here, we identified SEVEN IN ABSENTIA (SINA) ubiquitin ligases, which belong to the RING-type ligase family, upland cotton (Gossypium hirsutum). Twenty-four GhSINAs were characterized, and expression levels GhSINA7, GhSINA8, GhSINA9 upregulated at 24 h after inoculation with Verticillium...
The KNOX (KNOTTED1-like homeobox) transcription factors play an important role in leaf, shoot apical meristem and seed development respond to biotic abiotic stresses. In this study, we analyzed the diversity evolutionary history of gene family genome tetraploid cotton (Gossypium hirsutum). Forty-four putative genes were identified. All from seven higher plant species classified into KNOXI, KNOXII, KNATM clades based on a phylogenetic analysis. Chromosomal localization collinearity analysis...