A5100673284- Plant Pathogens and Fungal Diseases
- Animal Virus Infections Studies
- Virus-based gene therapy research
- Aquaculture disease management and microbiota
- RNA Interference and Gene Delivery
- Plant Pathogens and Resistance
- Viral Infections and Vectors
- Fungal and yeast genetics research
- Mosquito-borne diseases and control
- Toxin Mechanisms and Immunotoxins
- Plant-Microbe Interactions and Immunity
- Parvovirus B19 Infection Studies
- Polyamine Metabolism and Applications
- CRISPR and Genetic Engineering
- interferon and immune responses
- Ferroptosis and cancer prognosis
- Insect symbiosis and bacterial influences
- RNA and protein synthesis mechanisms
- Urinary Tract Infections Management
- Influenza Virus Research Studies
- Legume Nitrogen Fixing Symbiosis
- Powdery Mildew Fungal Diseases
- Microbial Inactivation Methods
- Customer churn and segmentation
- Bacterial Identification and Susceptibility Testing
Cotton Research Institute
2025
Chinese Academy of Agricultural Sciences
2025
Anhui Medical University
2024-2025
Sir Run Run Shaw Hospital
2025
Zhejiang University
2025
Zhengzhou University
2025
First Affiliated Hospital of Anhui Medical University
2025
Lanzhou University
2021-2024
City University of Hong Kong
2021-2024
Shanghai University of Traditional Chinese Medicine
2021
Therapeutic HPV vaccines that induce potent HPV-specific cellular immunity and eliminate pre-existing infections remain elusive. Among various candidates under development, those based on DNA constructs are considered promising because of their safety profile, stability, efficacy. However, the use electroporation (EP) as a main delivery method for such is notorious adverse effects like pain potentially irreversible muscle damage. Moreover, requirement specialized equipment adds to complexity...
Abstract Background Rice blast caused by the fungus Magnaporthe oryzae is an important disease in virtually every rice growing region of world, which leads to significant annual decreases grain quality and yield. To prevent disease, resistance genes have been cloned introduced into susceptible cultivars. However, can often be broken within few years release, due mutation cognate avirulence fungal field populations. Results better understand pattern M. isolates under natural selection forces,...
This study aimed to investigate the impact of cold atmospheric-pressure plasma (CAP) on multidrug-resistant (MDR) bacteria various surfaces under nosocomial circumstances and underlying mechanism. Four common MDR (carbapenem-resistant Acinetobacter baumannii, carbapenem-resistant Pseudomonas aeruginosa, methicillin-resistant Staphylococcus aureus, Klebsiella pneumoniae) were inoculated surfaces, which subsequently exposed CAP. Then from recovered diluted. The killing curve was analyzed...
Abstract Obese pregnant women in late pregnancy are more susceptible to uterine smooth muscle dysfunction, but the underlying mechanisms remain elusive. Here, elevated levels of fatty acid binding protein 4 (FABP4) myometrium obese at term, high‐fat diet (HFD)‐induced mice, and palmitic acid‐treated cells (USMCs), demonstrated. FABP4 plays a critical role transporting acids from extracellular intracellular compartment. Mechanistically, obesity promotes excessive uptake, leading aberrant...
An increasing number of critically ill patients are immunocompromised. These at high risk intensive care unit (ICU) admission because numerous complications. Acute respiratory failure due to severe community-acquired pneumonia (SCAP) is one the leading causes admission. Early targeted antibiotic therapy crucial for improving prognosis these patients. Metagenomic next-generation sequencing (mNGS) in bronchoalveolar lavage fluid (BALF) has shown significant value pathogen detection recent...
Properties of short-chain antimicrobial peptides (AMPs) depend on their primary structures. Brevibacillus laterosporus was previously found to secrete five AMPs. Herein, we discovered exogenously-added l-valine could regulate this strain produce novel AMPs (named as Brevilaterin V) with new Five Brevilaterins V linear were purified and characterized. They had high activities against 10 tested pathogenic bacteria. exhibited a good stability even treatment at 100 °C, or pH 2 12, for h....
Most alphaviruses are transmitted by mosquitoes and infect a wide range of insects vertebrates. However, Eilat virus (EILV) is defective for infecting vertebrate cells at multiple levels the viral life cycle. This host-restriction property renders EILV an attractive expression platform since it not infectious vertebrates therefore provides highly advantageous safety profile. Here, we investigated feasibility versatile EILV-based vectors. By replacing structural genes with those other...
Saffron (Crocus sativus L.) is a world-famous source of dye and spices an important medicinal plant, which cultivated on large scale Chongming Island (31.62° N, 121.39° E) in Shanghai, China. In August 2020, survey saffron was conducted this area, black spots were observed about 10% plants. Characteristics the disease were: The bottom corm darkened groove scattered could be after peeling off membranous leaves. junction lesions healthy parts light brown. As expanded, approximately 80% surface...
SLAMF8, the eighth member of Signaling Lymphocytic Activation Molecule Family (SLAMF), functions in regulation development and activity diverse immune cells as a costimulatory receptor within SLAMF family. Studies had revealed that SLAMF8 is expressed higher several autoimmune inflammation diseases tumors. Nevertheless, connection between pan-cancer remains undisclosed. The research investigated correlation various factors including microenvironment, microsatellite instability, novel...
Plant pathogens are important for community assembly and ecosystem functioning respond to a variety of abiotic biotic factors, which may change along elevational gradients. Thus, gradients valuable model system exploring how environmental, plant soil factors influence pathogen communities. Yet, these in natural ecosystems remains poorly understood. We examined the dynamics fungal gradients, as well mechanisms shaping dynamics, by combining field survey on Tibetan Plateau with global...