Małgorzata Lipińska-Gediga

ORCID: 0000-0002-9866-7684
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About
Contact & Profiles
Research Areas
  • Sepsis Diagnosis and Treatment
  • Frailty in Older Adults
  • Cardiac, Anesthesia and Surgical Outcomes
  • Intensive Care Unit Cognitive Disorders
  • Immune Response and Inflammation
  • Metabolomics and Mass Spectrometry Studies
  • Respiratory Support and Mechanisms
  • Hemodynamic Monitoring and Therapy
  • Palliative Care and End-of-Life Issues
  • Organ Donation and Transplantation
  • Renal function and acid-base balance
  • Pancreatitis Pathology and Treatment
  • Hip and Femur Fractures
  • Hyperglycemia and glycemic control in critically ill and hospitalized patients
  • Platelet Disorders and Treatments
  • Acute Kidney Injury Research
  • Biomarkers in Disease Mechanisms
  • Traumatic Brain Injury and Neurovascular Disturbances
  • Patient Dignity and Privacy
  • Prenatal Substance Exposure Effects
  • Neonatal and Maternal Infections
  • Nosocomial Infections in ICU
  • Clusterin in disease pathology
  • Cardiac Arrest and Resuscitation
  • Magnesium in Health and Disease

Wroclaw Medical University
2011-2024

University Hospital of Larissa
2021

Intensive Care Foundation
2019

Military Hospital
2017

Wroclaw University of Health and Sport Sciences
2009

Papieski Wydział Teologiczny we Wrocławiu
2008

To establish the prognostic and discriminative value of pro-atrial natriuretic peptide (pro-ANP) level in patients with severe sepsis or septic shock.An observational prospective study was conducted on 50 critically ill shock. Measurements procalcitonin (PCT) mid-regional pro-ANP were determined serum commercially available immunoluminometric tests.The median significantly higher non-survivors than survivors (P < 0.05) all consecutive days. No significant differences levels observed There a...

10.1007/s15010-011-0235-0 article EN cc-by-nc Infection 2012-01-11

Gastrointestinal symptoms are common in critically ill COVID-19 patients. There is currently no generally recognized method of assessing gastrointestinal injury unconscious or sedated intensive care unit (ICU) I-FABP (intestinal fatty acid binding protein) and citrulline have previously been studied as potential biomarkers enterocyte damage various tract diseases, changes the levels these markers may reflect intestinal wall COVID-19. Patients with critical COVID-19, diagnosed sepsis, septic...

10.3390/pathogens11121526 article EN cc-by Pathogens 2022-12-13

Introduction: Severe sepsis and septic shock are advanced clinical conditions representing the patient's response to infection having a variable but high mortality rate.Early evaluation of stage choice adequate treatment key factors for survival.Some study results suggest necessity daily procalcitonin (PCT) monitoring because its prognostic discriminative value.Material methods: An observational prospective was conducted evaluate value PCT kinetics in comparison absolute measurements.In...

10.5114/aoms.2016.57587 article EN cc-by-nc-sa Archives of Medical Science 2016-01-01

Sepsis, defined as a dysregulated host response to infection, causes the interruption of homeostasis resulting in metabolic changes. An examination patient metabolites, such amino acids, during early stage sepsis may facilitate diagnosing and assessing severity sepsis. The aim this study was compare patterns urine serum acids relative sepsis, septic shock survival. Urine samples were obtained from healthy volunteers (n = 15) once or patients within 24 h diagnosis shock. Concentrations 25...

10.1038/s41598-021-99482-8 article EN cc-by Scientific Reports 2021-10-07

Background: CD163, a cell membrane surface molecule specifically expressed by macrophages with an anti-inflammatory phenotype, participates in innate immunity. The purpose of the study was to evaluate clinical utility sCD163 septic patients comparison other parameters associated infections, mainly PCT, CRP and IL-18. Methods: Serum samples were obtained from 40 on ICU admission day, 3rd 5th days. control group consisted 30 healthy volunteers whom specimen collected once. An enzyme-linked...

10.3390/ijerph20032263 article EN International Journal of Environmental Research and Public Health 2023-01-27

The aim of this prospective, observational study was to assess whether changes in the level endocan, a marker endothelial damage, may be an indicator clinical deterioration and mortality critically ill COVID-19 patients. Endocan parameters were evaluated 40 patients with acute respiratory failure on days 1-5 after admission intensive care unit. levels not related degree failure, but presence cardiovascular failure. In endocan increased over first 5 (1.63, 2.50, 2.68, 2.77, 3.31 ng/mL, p =...

10.1038/s41598-023-48912-w article EN cc-by Scientific Reports 2023-12-15

Background: This study compares organ dysfunction, treatment strategies, and unfavorable outcome rates between pregnant nonpregnant women admitted to the ICU with severe COVID-19, highlighting increased susceptibility of respiratory infections due physiological changes. Methods: A retrospective, age-matched was conducted at a referral center specializing in critical care for women. Data from 14 pregnant/postpartum 11 were analyzed admission on days 3, 5, 7. Results: Acute distress syndrome...

10.3390/v17010051 article EN cc-by Viruses 2024-12-31

Exsanguination is an underestimated cause of treatment failures in patients with severe trauma or undergoing surgery. In some the primary dysfunction blood clot formation a direct massive loss. Patients without previous coagulation disorders are at risk coagulopathy following intraoperative post-traumatic bleeding, where local haemostasis does not warrant bleeding cessation.was to assess therapeutic value various components complex interdisciplinary approach, based on opinion experts...

10.2478/v10035-011-0073-x article EN Polish Journal of Surgery 2011-01-01

In response to an infection, the innate part of immune system is first line host defense. This non-specific but rapid, and a source information for next step acquired response. Findings that some cellular elements reveal properties placing them as interface between “innate” “adaptive” systems, others use newly discovered killing strategies, might change understanding how functions.

10.4172/2155-9899.s13-008 article EN Journal of Clinical & Cellular Immunology 2013-01-01

Abstract Background In Poland, little is known about the most serious cases of influenza that need admittance to intensive care unit (ICU), as well use extracorporeal respiratory support. Methods This was an electronic survey comprising ICUs in two administrative regions Poland. The aim study determine number patients with failure admitted ICU autumn–winter season 2018/2019. Furthermore, support, outcome and other pathogens detected airways were investigated. Results Influenza infection...

10.1186/s12879-021-06672-w article EN cc-by BMC Infectious Diseases 2021-09-15

Introduction Acute kidney injury (AKI) is a syndrome comprising multiple clinical conditions and the most common cause of AKI in critically ill patients sepsis. The pathophysiology sepsis-induced complex multifactorial. functional consequences during are dramatic, histological changes moderate do not entirely explain status. Resolved septicemia relative contraindication to organ procurement. Methods Two young with brain were hospitalized on ICU both developed sepsis due aspiration pneumonia....

10.1097/01.tp.0000525075.90041.83 article EN Transplantation 2017-08-01
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